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LRRC55 LRRC55 LOC115492063 LOC115492063 RAMP3 RAMP3 TESC TESC STIM1-2 STIM1-2 CAV1 CAV1 PSEN1 PSEN1 VMP1 VMP1 ANO6 ANO6 H0ZR32_TAEGU H0ZR32_TAEGU AMIGO1 AMIGO1 KCNQ1 KCNQ1 HTT HTT ENSTGUP00000024967 ENSTGUP00000024967 CFTR CFTR CLTRN CLTRN NPSR1 NPSR1 DRD4 DRD4 SHANK3 SHANK3 LOC100222362 LOC100222362 STIM1 STIM1 ACE2 ACE2 ENSTGUP00000020196 ENSTGUP00000020196 STAC3 STAC3 LOC100227551 LOC100227551 CHP1 CHP1 AKAP6 AKAP6 ABCC8 ABCC8 ATPSCKMT ATPSCKMT PINK1 PINK1 P2RX4 P2RX4 SLC17A8 SLC17A8 R3HDM2 R3HDM2 BAX BAX H0ZXR6_TAEGU H0ZXR6_TAEGU PDZK1 PDZK1 ARC ARC R3HDM1 R3HDM1 AKAP7 AKAP7 CACNG2 CACNG2 F2 F2 CAV3 CAV3 STIM2 STIM2 TRPC1 TRPC1 ATP1B3 ATP1B3 EDN1 EDN1 PIRT PIRT PLCG1 PLCG1 PLCG2 PLCG2 CACNG4 CACNG4 CNTD1 CNTD1 ENSTGUP00000002856 ENSTGUP00000002856 EDNRA EDNRA RNF207 RNF207 LRRC38 LRRC38 PKD2 PKD2 STAC STAC SLC9A1 SLC9A1 H0YQI8_TAEGU H0YQI8_TAEGU F2RL3 F2RL3 IFNGR2 IFNGR2 LOC100221679 LOC100221679 CX3CL1 CX3CL1 ATP1B2 ATP1B2 ENSTGUP00000033290 ENSTGUP00000033290 SRI SRI APLNR APLNR CAPN3 CAPN3 THY1 THY1 ADCYAP1R1 ADCYAP1R1 H0ZNJ6_TAEGU H0ZNJ6_TAEGU WNK2 WNK2 AMIGO2 AMIGO2 CDK5 CDK5 H0ZI74_TAEGU H0ZI74_TAEGU WNK1 WNK1 CACNB4 CACNB4 P2RX1 P2RX1 ENSTGUP00000036048 ENSTGUP00000036048 ENSTGUP00000036039 ENSTGUP00000036039
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC55Leucine-rich repeat-containing protein 55. (281 aa)
LOC115492063Glucose-6-phosphate 1-dehydrogenase. (540 aa)
RAMP3Receptor activity modifying protein 3. (191 aa)
TESCCalcineurin B homologous protein 3 isoform X4. (337 aa)
STIM1-2Stromal interaction molecule 1 isoform X6. (422 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
VMP1Vacuole membrane protein 1. (406 aa)
ANO6Anoctamin. (907 aa)
H0ZR32_TAEGUUncharacterized protein; Belongs to the potassium channel family. (510 aa)
AMIGO1Amphoterin-induced protein 1. (496 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (691 aa)
HTTUncharacterized protein. (3107 aa)
ENSTGUP00000024967annotation not available (473 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
CLTRNCollectrin domain-containing protein. (229 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (376 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (364 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (2565 aa)
LOC100222362Phosphoinositide phospholipase C. (1311 aa)
STIM1Stromal interaction molecule 1. (1283 aa)
ACE2Angiotensin-converting enzyme. (804 aa)
ENSTGUP000000201961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1. (1281 aa)
STAC3Uncharacterized protein. (643 aa)
LOC100227551Uncharacterized protein. (186 aa)
CHP1Calcineurin like EF-hand protein 1. (196 aa)
AKAP6A-kinase anchoring protein 6. (2302 aa)
ABCC8ATP binding cassette subfamily C member 8. (1620 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (229 aa)
PINK1PTEN induced kinase 1. (515 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
SLC17A8MFS domain-containing protein. (590 aa)
R3HDM2Uncharacterized protein. (1026 aa)
BAXBCL2 associated X, apoptosis regulator. (225 aa)
H0ZXR6_TAEGUG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (429 aa)
PDZK1PDZ domain containing 1. (515 aa)
ARCActivity regulated cytoskeleton associated protein. (404 aa)
R3HDM1R3H domain containing 1. (1165 aa)
AKAP7A-kinase anchoring protein 7. (407 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (608 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
STIM2Stromal interaction molecule 2. (705 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (774 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (289 aa)
EDN1Endothelin 1. (202 aa)
PIRTPhosphoinositide interacting regulator of transient receptor potential channels. (134 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1282 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
CNTD1Cyclin N-terminal domain containing 1. (328 aa)
ENSTGUP00000002856annotation not available (519 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
RNF207Ring finger protein 207. (637 aa)
LRRC38Leucine rich repeat containing 38. (325 aa)
PKD2Uncharacterized protein. (903 aa)
STACSH3 and cysteine rich domain. (405 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (803 aa)
H0YQI8_TAEGUFibronectin type-III domain-containing protein. (323 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (381 aa)
IFNGR2Interferon gamma receptor 2 isoform X2. (340 aa)
LOC100221679Uncharacterized protein. (67 aa)
CX3CL1Uncharacterized protein. (429 aa)
ATP1B2Taeniopygia guttata ATPase Na+/K+ transporting subunit beta 2 (ATP1B2), mRNA. (488 aa)
ENSTGUP00000033290annotation not available (332 aa)
SRIPutative sorcin transcript variant 1. (323 aa)
APLNRUncharacterized protein. (371 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (809 aa)
THY1Thy-1 cell surface antigen. (241 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (517 aa)
H0ZNJ6_TAEGUUncharacterized protein. (253 aa)
WNK2WNK lysine deficient protein kinase 2. (2249 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
CDK5Cyclin-dependent-like kinase 5. (808 aa)
H0ZI74_TAEGUAKAP7_NLS domain-containing protein. (671 aa)
WNK1WNK lysine deficient protein kinase 1. (2915 aa)
CACNB4SH3 domain-containing protein. (478 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
ENSTGUP00000036048annotation not available (549 aa)
ENSTGUP00000036039annotation not available (290 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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