(26 nodes) Aorta development network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
	PKD2	Uncharacterized protein. (903 aa)
	FKBP10	Peptidyl-prolyl cis-trans isomerase FKBP10. (571 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	LOC100230282	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (586 aa)
	ENG	Endoglin. (631 aa)
	SRF	Serum response factor. (485 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1216 aa)
	DCTN5	Dynactin subunit 5. (524 aa)
	SMAD6	SMAD family member 6. (477 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	SUFU	Suppressor of fused homolog. (482 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (683 aa)
	CHD7	Chromodomain helicase DNA binding protein 7. (3012 aa)
	HECTD1	Uncharacterized protein. (2570 aa)
	PRDM1	PR/SET domain 1. (789 aa)
	CNTRL	Centriolin. (2295 aa)
	LOC115491405	Serine/threonine-protein kinase receptor R3 isoform X2. (493 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1232 aa)
	CHD8	Chromodomain helicase DNA binding protein 8. (1744 aa)
	NPRL3	NPR3 like, GATOR1 complex subunit. (710 aa)
	PLXND1	Plexin D1. (1929 aa)
	LEP	Taeniopygia guttata leptin (LEP), mRNA. (168 aa)
	LOX	Lysyl oxidase. (453 aa)
	CHD9	Chromodomain helicase DNA binding protein 9. (2890 aa)
	NGFR	Tumor necrosis factor receptor superfamily member 16. (475 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL4	JAG1	ENSTGUP00000011110	ENSTGUP00000006280	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.462
ENG	LOC100230282	ENSTGUP00000003672	ENSTGUP00000003374	Endoglin.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.723
ENG	LOC115491405	ENSTGUP00000003672	ENSTGUP00000021756	Endoglin.	Serine/threonine-protein kinase receptor R3 isoform X2.	0.723
FGF8	NGFR	ENSTGUP00000010279	ENSTGUP00000036482	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Tumor necrosis factor receptor superfamily member 16.	0.674
JAG1	DLL4	ENSTGUP00000006280	ENSTGUP00000011110	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.462
LEP	SMAD6	ENSTGUP00000028222	ENSTGUP00000009751	Taeniopygia guttata leptin (LEP), mRNA.	SMAD family member 6.	0.516
LOC100230282	ENG	ENSTGUP00000003374	ENSTGUP00000003672	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Endoglin.	0.723
LOC100230282	SMAD6	ENSTGUP00000003374	ENSTGUP00000009751	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	SMAD family member 6.	0.576
LOC115491405	ENG	ENSTGUP00000021756	ENSTGUP00000003672	Serine/threonine-protein kinase receptor R3 isoform X2.	Endoglin.	0.723
LOC115491405	SMAD6	ENSTGUP00000021756	ENSTGUP00000009751	Serine/threonine-protein kinase receptor R3 isoform X2.	SMAD family member 6.	0.576
NGFR	FGF8	ENSTGUP00000036482	ENSTGUP00000010279	Tumor necrosis factor receptor superfamily member 16.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.674
SMAD6	LEP	ENSTGUP00000009751	ENSTGUP00000028222	SMAD family member 6.	Taeniopygia guttata leptin (LEP), mRNA.	0.516
SMAD6	LOC100230282	ENSTGUP00000009751	ENSTGUP00000003374	SMAD family member 6.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.576
SMAD6	LOC115491405	ENSTGUP00000009751	ENSTGUP00000021756	SMAD family member 6.	Serine/threonine-protein kinase receptor R3 isoform X2.	0.576