(45 nodes) Positive regulation of T cell proliferation network (Taeniopygia guttata)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	HHLA2	HERV-H LTR-associating 2. (351 aa)
	VTCN1	Uncharacterized protein. (242 aa)
	CD86	CD86 molecule. (302 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (553 aa)
	SLC7A1	AA_permease_C domain-containing protein. (624 aa)
	TNFSF13B	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (288 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (847 aa)
	TNFRSF13C	Uncharacterized protein. (211 aa)
	NCK2	NCK adaptor protein 2. (380 aa)
	IGF2	IlGF domain-containing protein. (225 aa)
	LOC115496886	Protein kinase domain-containing protein. (554 aa)
	LOC100219822	ZP domain-containing protein. (459 aa)
	H0Z7I3_TAEGU	Uncharacterized protein. (403 aa)
	SASH3	Uncharacterized protein. (568 aa)
	CD274	CD274 molecule. (360 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
	IL1B	Interleukin-1; Belongs to the IL-1 family. (299 aa)
	IL6	Interleukin 6. (221 aa)
	SYK	Tyrosine-protein kinase. (668 aa)
	ZAP70	Tyrosine-protein kinase. (609 aa)
	ANXA1	Annexin. (364 aa)
	ENSTGUP00000037897	annotation not available (399 aa)
	LOC115496603	Zona pellucida sperm-binding protein 3-like. (426 aa)
	IL21	Interleukin; Belongs to the IL-15/IL-21 family. (194 aa)
	FADD	Fas associated via death domain. (221 aa)
	ENSTGUP00000034391	Mucin-2-like. (483 aa)
	ENSTGUP00000034101	annotation not available (743 aa)
	LOC100221605	Programmed cell death 1 ligand 2. (322 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (199 aa)
	CARD11	Caspase recruitment domain family member 11. (1167 aa)
	IL6ST	Interleukin 6 signal transducer. (921 aa)
	ENSTGUP00000031809	annotation not available (496 aa)
	CCL19	C-C motif chemokine ligand 19. (152 aa)
	LEP	Taeniopygia guttata leptin (LEP), mRNA. (168 aa)
	PTPRC	Uncharacterized protein. (1194 aa)
	ENSTGUP00000027497	annotation not available (154 aa)
	TFRC	Transferrin receptor. (776 aa)
	ENSTGUP00000024453	HLA class II histocompatibility antigen, DM beta chain-like. (551 aa)
	ENSTGUP00000024289	Basic proline-rich protein-like. (206 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	ENSTGUP00000023651	annotation not available (927 aa)
	H0ZIT4_TAEGU	Uncharacterized protein. (954 aa)
	H1A352_TAEGU	Uncharacterized protein. (360 aa)
	CD276	Ig-like domain-containing protein. (420 aa)
	CD28	CD28 molecule. (222 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	TFRC	ENSTGUP00000038342	ENSTGUP00000027452	Annexin.	Transferrin receptor.	0.550
CARD11	FADD	ENSTGUP00000032603	ENSTGUP00000034889	Caspase recruitment domain family member 11.	Fas associated via death domain.	0.407
CARD11	LOC115496886	ENSTGUP00000032603	ENSTGUP00000007063	Caspase recruitment domain family member 11.	Protein kinase domain-containing protein.	0.471
CARD11	RIPK2	ENSTGUP00000032603	ENSTGUP00000012150	Caspase recruitment domain family member 11.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.471
CARD11	SYK	ENSTGUP00000032603	ENSTGUP00000000435	Caspase recruitment domain family member 11.	Tyrosine-protein kinase.	0.556
CARD11	TRAF6	ENSTGUP00000032603	ENSTGUP00000024238	Caspase recruitment domain family member 11.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.807
CARD11	ZAP70	ENSTGUP00000032603	ENSTGUP00000000339	Caspase recruitment domain family member 11.	Tyrosine-protein kinase.	0.655
CCL19	PTPRC	ENSTGUP00000030305	ENSTGUP00000027581	C-C motif chemokine ligand 19.	Uncharacterized protein.	0.414
CD274	CD86	ENSTGUP00000005180	ENSTGUP00000013741	CD274 molecule.	CD86 molecule.	0.646
CD274	VTCN1	ENSTGUP00000005180	ENSTGUP00000013760	CD274 molecule.	Uncharacterized protein.	0.562
CD276	CD86	ENSTGUP00000018774	ENSTGUP00000013741	Ig-like domain-containing protein.	CD86 molecule.	0.495
CD28	CD86	ENSTGUP00000017034	ENSTGUP00000013741	CD28 molecule.	CD86 molecule.	0.987
CD86	CD274	ENSTGUP00000013741	ENSTGUP00000005180	CD86 molecule.	CD274 molecule.	0.646
CD86	CD276	ENSTGUP00000013741	ENSTGUP00000018774	CD86 molecule.	Ig-like domain-containing protein.	0.495
CD86	CD28	ENSTGUP00000013741	ENSTGUP00000017034	CD86 molecule.	CD28 molecule.	0.987
CD86	ENSTGUP00000031809	ENSTGUP00000013741	ENSTGUP00000031809	CD86 molecule.	annotation not available	0.495
CD86	IL15	ENSTGUP00000013741	ENSTGUP00000033579	CD86 molecule.	Interleukin; Belongs to the IL-15/IL-21 family.	0.584
CD86	IL1B	ENSTGUP00000013741	ENSTGUP00000003479	CD86 molecule.	Interleukin-1; Belongs to the IL-1 family.	0.610
CD86	IL6	ENSTGUP00000013741	ENSTGUP00000002805	CD86 molecule.	Interleukin 6.	0.575
CD86	PTPRC	ENSTGUP00000013741	ENSTGUP00000027581	CD86 molecule.	Uncharacterized protein.	0.610