(88 nodes) Perikaryon network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OLFM1	Olfactomedin-like domain-containing protein. (503 aa)
	LOC115491408	FHA domain-containing protein. (454 aa)
	NGFR	Tumor necrosis factor receptor superfamily member 16. (475 aa)
	FMR1	Fragile X mental retardation 1. (548 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
	NEURL1	Neuralized E3 ubiquitin protein ligase 1. (736 aa)
	TH	Tyrosine hydroxylase. (491 aa)
	PDE11A	Phosphodiesterase. (915 aa)
	SYAP1	Synapse associated protein 1. (358 aa)
	PCSK1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1541 aa)
	LOC100228395	Uncharacterized protein. (502 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4. (483 aa)
	OPN4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (517 aa)
	KLHL6	Kelch like family member 6. (610 aa)
	KLHL24	Kelch like family member 24. (600 aa)
	TOP1	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (764 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (330 aa)
	LOC100219793	Cyclic AMP-dependent transcription factor ATF-1-like. (1581 aa)
	H0YY70_TAEGU	G_PROTEIN_RECEP_F1_2 domain-containing protein. (556 aa)
	NSMF	NMDA receptor synaptonuclear signaling and neuronal migration factor. (533 aa)
	AZIN2	Antizyme inhibitor 2. (458 aa)
	PAM	Peptidylglycine alpha-amidating monooxygenase. (914 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1899 aa)
	G3BP1	G3BP stress granule assembly factor 1. (483 aa)
	CIB3	Uncharacterized protein. (231 aa)
	ZPR1	ZPR1 zinc finger. (449 aa)
	UCN	Urocortin. (99 aa)
	BRD1	Bromodomain containing 1. (1205 aa)
	SMN1	Tudor domain-containing protein. (317 aa)
	ENSTGUP00000038675	annotation not available (487 aa)
	RGS7BP	Regulator of G protein signaling 7 binding protein. (255 aa)
	KCNB2	Potassium voltage-gated channel Shab-related subfamily B member 2. (910 aa)
	OLFM3	Olfactomedin 3. (458 aa)
	ADCYAP1	Adenylate cyclase activating polypeptide 1. (172 aa)
	OLFM2	Olfactomedin 2. (482 aa)
	TMEM266	Transmembrane protein 266. (562 aa)
	PTPRD	Protein tyrosine phosphatase receptor type D. (1919 aa)
	PRPH	Peripherin; Belongs to the intermediate filament family. (392 aa)
	GRIP1	Glutamate receptor interacting protein 1. (1167 aa)
	NGB	Neuroglobin; Belongs to the globin family. (161 aa)
	AMIGO1	Amphoterin-induced protein 1. (496 aa)
	CPLX1	Complexin 1. (164 aa)
	TMEM100	Transmembrane protein 100. (134 aa)
	LOC100219522	NAD-dependent protein deacetylase sirtuin-2-like. (455 aa)
	ENSTGUP00000027548	annotation not available (629 aa)
	CHRNB2	Cholinergic receptor nicotinic beta 2 subunit. (706 aa)
	DBNL	Drebrin-like protein. (460 aa)
	ASTN1	Astrotactin 1. (1293 aa)
	APP	Amyloid beta precursor protein. (797 aa)
	H1A0R1_TAEGU	MCRS_N domain-containing protein. (706 aa)
	CIB1	Calcium and integrin binding 1. (213 aa)
	KCNB1	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (862 aa)
	SHTN1	Shootin 1. (682 aa)
	C9orf72	C9orf72-SMCR8 complex subunit. (481 aa)
	GNRH1	Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (357 aa)
	CRMP1	Collapsin response mediator protein 1. (683 aa)
	LRRK2	Leucine rich repeat kinase 2. (2509 aa)
	LOC115492957	Sodium channel subunit beta-1-like. (212 aa)
	RUFY3	RUN and FYVE domain containing 3. (664 aa)
	CPLX2	Complexin-1/2. (125 aa)
	ENSTGUP00000018634	annotation not available (359 aa)
	SYT11	Synaptotagmin 11. (484 aa)
	SLC17A8	MFS domain-containing protein. (590 aa)
	KCNE3	Potassium voltage-gated channel subfamily E regulatory subunit 3. (101 aa)
	ENO2	Enolase 2. (485 aa)
	H0ZSC5_TAEGU	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (638 aa)
	LOC100223483	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (544 aa)
	DHX36	DEAH-box helicase 36. (1047 aa)
	LOC100217613	BH4_AAA_HYDROXYL_2 domain-containing protein. (459 aa)
	VIP	Vasoactive intestinal peptide. (215 aa)
	OPRM1	Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (410 aa)
	SERPINI1	Putative neuroserpin variant 4; Belongs to the serpin family. (428 aa)
	EPM2A	EPM2A glucan phosphatase, laforin. (319 aa)
	KCNK1	Potassium channel subfamily K member. (336 aa)
	SLC5A7	Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (578 aa)
	CDK5	Cyclin-dependent-like kinase 5. (808 aa)
	SLC4A10	Anion exchange protein. (1099 aa)
	AMIGO2	Adhesion molecule with Ig like domain 2. (521 aa)
	LOC100217684	Reticulon 4 receptor. (482 aa)
	TTLL7	Tubulin tyrosine ligase like 7. (911 aa)
	RTN4RL1	Reticulon-4 receptor-like 1. (455 aa)
	ATOH7	Atonal bHLH transcription factor 7. (151 aa)
	LOC100219793-2	Disco interacting protein 2 homolog B. (1572 aa)
	KNDC1	Uncharacterized protein. (1910 aa)
	LOC100217684-2	Reticulon-4 receptor. (482 aa)
	ENSTGUP00000035196	annotation not available (218 aa)
	GIGYF2	GYF domain-containing protein. (1277 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	CDK5	ENSTGUP00000029357	ENSTGUP00000030783	Amyloid beta precursor protein.	Cyclin-dependent-like kinase 5.	0.504
APP	FMR1	ENSTGUP00000029357	ENSTGUP00000037101	Amyloid beta precursor protein.	Fragile X mental retardation 1.	0.424
APP	LOC100228395	ENSTGUP00000029357	ENSTGUP00000006046	Amyloid beta precursor protein.	Uncharacterized protein.	0.425
APP	NGFR	ENSTGUP00000029357	ENSTGUP00000036482	Amyloid beta precursor protein.	Tumor necrosis factor receptor superfamily member 16.	0.776
APP	SYT11	ENSTGUP00000029357	ENSTGUP00000017690	Amyloid beta precursor protein.	Synaptotagmin 11.	0.527
CDK5	APP	ENSTGUP00000030783	ENSTGUP00000029357	Cyclin-dependent-like kinase 5.	Amyloid beta precursor protein.	0.504
CDK5	CRMP1	ENSTGUP00000030783	ENSTGUP00000021536	Cyclin-dependent-like kinase 5.	Collapsin response mediator protein 1.	0.656
CHRNB2	LOC100228395	ENSTGUP00000028071	ENSTGUP00000006046	Cholinergic receptor nicotinic beta 2 subunit.	Uncharacterized protein.	0.423
CRHBP	UCN	ENSTGUP00000004187	ENSTGUP00000037922	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urocortin.	0.862
CRMP1	CDK5	ENSTGUP00000021536	ENSTGUP00000030783	Collapsin response mediator protein 1.	Cyclin-dependent-like kinase 5.	0.656
FMR1	APP	ENSTGUP00000037101	ENSTGUP00000029357	Fragile X mental retardation 1.	Amyloid beta precursor protein.	0.424
FMR1	G3BP1	ENSTGUP00000037101	ENSTGUP00000000779	Fragile X mental retardation 1.	G3BP stress granule assembly factor 1.	0.609
G3BP1	FMR1	ENSTGUP00000000779	ENSTGUP00000037101	G3BP stress granule assembly factor 1.	Fragile X mental retardation 1.	0.609
GNRH1	VIP	ENSTGUP00000030657	ENSTGUP00000011533	Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.	Vasoactive intestinal peptide.	0.402
KCNB1	KCNB2	ENSTGUP00000029981	ENSTGUP00000021886	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family.	Potassium voltage-gated channel Shab-related subfamily B member 2.	0.493
KCNB2	KCNB1	ENSTGUP00000021886	ENSTGUP00000029981	Potassium voltage-gated channel Shab-related subfamily B member 2.	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family.	0.493
LOC100217613	TH	ENSTGUP00000011623	ENSTGUP00000009606	BH4_AAA_HYDROXYL_2 domain-containing protein.	Tyrosine hydroxylase.	0.901
LOC100217684	NGFR	ENSTGUP00000031679	ENSTGUP00000036482	Reticulon 4 receptor.	Tumor necrosis factor receptor superfamily member 16.	0.617
LOC100217684-2	NGFR	ENSTGUP00000033931	ENSTGUP00000036482	Reticulon-4 receptor.	Tumor necrosis factor receptor superfamily member 16.	0.617
LOC100228395	APP	ENSTGUP00000006046	ENSTGUP00000029357	Uncharacterized protein.	Amyloid beta precursor protein.	0.425