(22 nodes) T cell selection network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THEMIS	Thymocyte selection associated. (683 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (199 aa)
	ENSTGUP00000033254	annotation not available (279 aa)
	CARD11	Caspase recruitment domain family member 11. (1167 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	CD3E	T-cell surface glycoprotein CD3 epsilon chain. (212 aa)
	IL6R	Interleukin 6 receptor. (460 aa)
	PTPRC	Uncharacterized protein. (1194 aa)
	LOC100222416	Ig_4 domain-containing protein. (512 aa)
	TBX21	T-box transcription factor 21. (599 aa)
	CD74	Uncharacterized protein. (289 aa)
	CD4	Ig-like domain-containing protein. (396 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1326 aa)
	BCL11B	BAF chromatin remodeling complex subunit BCL11B. (883 aa)
	BATF	Basic leucine zipper ATF-like transcription factor. (170 aa)
	TOX	Thymocyte selection associated high mobility group box. (539 aa)
	SRF	Serum response factor. (485 aa)
	IL6	Interleukin 6. (221 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	MTOR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (1322 aa)
	GATA3	GATA binding protein 3. (443 aa)
	ZAP70	Tyrosine-protein kinase. (609 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG5	ENSTGUP00000033254	ENSTGUP00000032015	ENSTGUP00000033254	Autophagy protein 5; Involved in autophagic vesicle formation.	annotation not available	0.436
ATG5	MTOR	ENSTGUP00000032015	ENSTGUP00000002370	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.436
BATF	BCL11B	ENSTGUP00000012582	ENSTGUP00000013082	Basic leucine zipper ATF-like transcription factor.	BAF chromatin remodeling complex subunit BCL11B.	0.577
BCL11B	BATF	ENSTGUP00000013082	ENSTGUP00000012582	BAF chromatin remodeling complex subunit BCL11B.	Basic leucine zipper ATF-like transcription factor.	0.577
CARD11	ZAP70	ENSTGUP00000032603	ENSTGUP00000000339	Caspase recruitment domain family member 11.	Tyrosine-protein kinase.	0.655
CCR7	CD3E	ENSTGUP00000002421	ENSTGUP00000029609	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	T-cell surface glycoprotein CD3 epsilon chain.	0.468
CCR7	CD4	ENSTGUP00000002421	ENSTGUP00000013698	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Ig-like domain-containing protein.	0.724
CCR7	IL6	ENSTGUP00000002421	ENSTGUP00000002805	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Interleukin 6.	0.508
CCR7	LOC100222416	ENSTGUP00000002421	ENSTGUP00000025122	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Ig_4 domain-containing protein.	0.443
CCR7	PTPRC	ENSTGUP00000002421	ENSTGUP00000027581	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.525
CCR7	TBX21	ENSTGUP00000002421	ENSTGUP00000023254	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	T-box transcription factor 21.	0.422
CD3E	CCR7	ENSTGUP00000029609	ENSTGUP00000002421	T-cell surface glycoprotein CD3 epsilon chain.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.468
CD3E	CD4	ENSTGUP00000029609	ENSTGUP00000013698	T-cell surface glycoprotein CD3 epsilon chain.	Ig-like domain-containing protein.	0.833
CD3E	LOC100222416	ENSTGUP00000029609	ENSTGUP00000025122	T-cell surface glycoprotein CD3 epsilon chain.	Ig_4 domain-containing protein.	0.998
CD3E	PTPRC	ENSTGUP00000029609	ENSTGUP00000027581	T-cell surface glycoprotein CD3 epsilon chain.	Uncharacterized protein.	0.752
CD3E	ZAP70	ENSTGUP00000029609	ENSTGUP00000000339	T-cell surface glycoprotein CD3 epsilon chain.	Tyrosine-protein kinase.	0.968
CD4	CCR7	ENSTGUP00000013698	ENSTGUP00000002421	Ig-like domain-containing protein.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.724
CD4	CD3E	ENSTGUP00000013698	ENSTGUP00000029609	Ig-like domain-containing protein.	T-cell surface glycoprotein CD3 epsilon chain.	0.833
CD4	GATA3	ENSTGUP00000013698	ENSTGUP00000002200	Ig-like domain-containing protein.	GATA binding protein 3.	0.551
CD4	IL15	ENSTGUP00000013698	ENSTGUP00000033579	Ig-like domain-containing protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.739