STRINGSTRING
RIOX1 RIOX1 IHH IHH IGFBP5 IGFBP5 CCN1 CCN1 ENSTGUP00000036312 ENSTGUP00000036312 BMPR1B BMPR1B ENSTGUP00000033975 ENSTGUP00000033975 ILK ILK CEBPB-2 CEBPB-2 DDR2 DDR2 IL6ST IL6ST SUCO SUCO LOC115493314 LOC115493314 CEBPB CEBPB LOC100229115 LOC100229115 CTHRC1 CTHRC1 LOC100231082-2 LOC100231082-2 ACVR1 ACVR1 ATRAID ATRAID LRP5 LRP5 FFAR4 FFAR4 TWIST2 TWIST2 REST REST TP63 TP63 BMP6 BMP6 OSTN OSTN FGF23 FGF23 TNFAIP6 TNFAIP6 TMEM64 TMEM64 WWTR1 WWTR1 MTRF1L MTRF1L FNDC3B FNDC3B CEBPD CEBPD CHRD CHRD ATF4 ATF4 BMPR2 BMPR2 SMAD6 SMAD6 FAM20C FAM20C GDPD2 GDPD2 TMEM119 TMEM119 WDR63 WDR63 VEGFC VEGFC JAG1 JAG1 BMPR1A BMPR1A ZHX3 ZHX3 CTNNB1 CTNNB1 DDX5 DDX5 NPNT NPNT SKI SKI SOX9 SOX9 NBR1 NBR1 LOC100231082 LOC100231082 IL6 IL6 SMAD1 SMAD1 TWIST1 TWIST1 NOCT NOCT RANBP3L RANBP3L AREG AREG BAMBI BAMBI ID3 ID3 RORB RORB SHH SHH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66. (579 aa)
IHHIndian hedgehog signaling molecule. (408 aa)
IGFBP5Insulin like growth factor binding protein 5. (269 aa)
CCN1Cellular communication network factor 1. (412 aa)
ENSTGUP00000036312annotation not available (479 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ENSTGUP00000033975annotation not available (497 aa)
ILKIntegrin linked kinase. (676 aa)
CEBPB-2CCAAT enhancer binding protein beta. (324 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (1179 aa)
IL6STInterleukin 6 signal transducer. (921 aa)
SUCOSUN domain containing ossification factor. (1247 aa)
LOC115493314Translation initiation factor IF-2-like. (505 aa)
CEBPBCCAAT/enhancer-binding protein. (324 aa)
LOC100229115Fam20C domain-containing protein. (536 aa)
CTHRC1Collagen triple helix repeat containing 1. (468 aa)
LOC100231082-2Discoidin domain-containing receptor 2-like. (873 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (549 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1595 aa)
FFAR4Free fatty acid receptor 4. (354 aa)
TWIST2Twist family bHLH transcription factor 2. (160 aa)
RESTRE1 silencing transcription factor. (893 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (702 aa)
BMP6Bone morphogenetic protein 6. (414 aa)
OSTNUncharacterized protein. (144 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (253 aa)
TNFAIP6TNF alpha induced protein 6. (296 aa)
TMEM64Transmembrane protein 64. (713 aa)
WWTR1WW domain containing transcription regulator 1. (382 aa)
MTRF1LF-box protein 5. (592 aa)
FNDC3BFibronectin type III domain containing 3B. (1139 aa)
CEBPDCCAAT/enhancer-binding protein. (206 aa)
CHRDChordin. (1135 aa)
ATF4Activating transcription factor 4. (354 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
SMAD6SMAD family member 6. (477 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (560 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (567 aa)
TMEM119Transmembrane protein 119. (354 aa)
WDR63WD repeat domain 63. (824 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (468 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1216 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
ZHX3Zinc fingers and homeoboxes 3. (954 aa)
CTNNB1Catenin beta 1. (781 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (781 aa)
NPNTUncharacterized protein. (531 aa)
SKISKI proto-oncogene. (714 aa)
SOX9SRY-box transcription factor 9. (474 aa)
NBR1NBR1 autophagy cargo receptor. (1013 aa)
LOC100231082Uncharacterized protein. (873 aa)
IL6Interleukin 6. (221 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
TWIST1Twist family bHLH transcription factor 1. (147 aa)
NOCTEndo/exonuclease/phosphatase domain-containing protein. (418 aa)
RANBP3LRAN binding protein 3 like. (544 aa)
AREGAmphiregulin. (195 aa)
BAMBIBMP and activin membrane bound inhibitor. (261 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (125 aa)
RORBRAR related orphan receptor B. (464 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (425 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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