STRINGSTRING
MTRF1L MTRF1L SHH SHH SMAD1 SMAD1 IL6 IL6 LOC100231082 LOC100231082 NPNT NPNT CTNNB1 CTNNB1 ZHX3 ZHX3 BMPR1A BMPR1A JAG1 JAG1 WDR63 WDR63 TMEM119 TMEM119 GDPD2 GDPD2 FAM20C FAM20C BMPR2 BMPR2 CEBPD CEBPD WWTR1 WWTR1 BMP6 BMP6 TP63 TP63 FFAR4 FFAR4 LRP5 LRP5 ATRAID ATRAID ACVR1 ACVR1 LOC100231082-2 LOC100231082-2 CTHRC1 CTHRC1 LOC100229115 LOC100229115 CEBPB CEBPB LOC115493314 LOC115493314 SUCO SUCO IHH IHH CCN1 CCN1 ENSTGUP00000036312 ENSTGUP00000036312 BMPR1B BMPR1B ENSTGUP00000033975 ENSTGUP00000033975 ILK ILK CEBPB-2 CEBPB-2 DDR2 DDR2 IL6ST IL6ST
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTRF1LF-box protein 5. (592 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (425 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
IL6Interleukin 6. (221 aa)
LOC100231082Uncharacterized protein. (873 aa)
NPNTUncharacterized protein. (531 aa)
CTNNB1Catenin beta 1. (781 aa)
ZHX3Zinc fingers and homeoboxes 3. (954 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1216 aa)
WDR63WD repeat domain 63. (824 aa)
TMEM119Transmembrane protein 119. (354 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (567 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (560 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
CEBPDCCAAT/enhancer-binding protein. (206 aa)
WWTR1WW domain containing transcription regulator 1. (382 aa)
BMP6Bone morphogenetic protein 6. (414 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (702 aa)
FFAR4Free fatty acid receptor 4. (354 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1595 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (549 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
LOC100231082-2Discoidin domain-containing receptor 2-like. (873 aa)
CTHRC1Collagen triple helix repeat containing 1. (468 aa)
LOC100229115Fam20C domain-containing protein. (536 aa)
CEBPBCCAAT/enhancer-binding protein. (324 aa)
LOC115493314Translation initiation factor IF-2-like. (505 aa)
SUCOSUN domain containing ossification factor. (1247 aa)
IHHIndian hedgehog signaling molecule. (408 aa)
CCN1Cellular communication network factor 1. (412 aa)
ENSTGUP00000036312annotation not available (479 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ENSTGUP00000033975annotation not available (497 aa)
ILKIntegrin linked kinase. (676 aa)
CEBPB-2CCAAT enhancer binding protein beta. (324 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (1179 aa)
IL6STInterleukin 6 signal transducer. (921 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.