STRINGSTRING
SMAD2 SMAD2 SMAD7 SMAD7 CITED4 CITED4 SMAD5 SMAD5 DROSHA DROSHA RANBP3L RANBP3L DAB2 DAB2 SMAD1 SMAD1 SKI SKI LOC100230282 LOC100230282 TGFBR2 TGFBR2 LOC100224677 LOC100224677 AXIN2 AXIN2 AXIN1 AXIN1 DDX5 DDX5 CTNNB1 CTNNB1 BMPR1A BMPR1A MYOCD MYOCD TGFBR1 TGFBR1 SMURF1 SMURF1 SMAD6 SMAD6 TGFBRAP1 TGFBRAP1 CREB3L1 CREB3L1 SKIL SKIL SMAD9 SMAD9 HMGA2 HMGA2 H0ZVJ8_TAEGU H0ZVJ8_TAEGU MEF2A MEF2A ENSTGUP00000020434 ENSTGUP00000020434 MAGI2-2 MAGI2-2 LOC115491405 LOC115491405 SMURF2 SMURF2 ENSTGUP00000023270 ENSTGUP00000023270 PPM1A PPM1A ZC3H3 ZC3H3 SMAD3 SMAD3 SKOR1 SKOR1 RANBP3 RANBP3 H0Z191_TAEGU H0Z191_TAEGU ACVR1B ACVR1B ACVR1 ACVR1 USP9X USP9X PMEPA1 PMEPA1 FOS FOS SNW1 SNW1 ENSTGUP00000031898 ENSTGUP00000031898 SMAD4 SMAD4 BMPR1B BMPR1B ENSTGUP00000034670 ENSTGUP00000034670 INTS8 INTS8 MAGI2 MAGI2 SAV1 SAV1 PURB PURB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD2Mothers against decapentaplegic homolog. (487 aa)
SMAD7MH1 domain-containing protein. (392 aa)
CITED4Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (204 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
DROSHADrosha ribonuclease III. (1336 aa)
RANBP3LRAN binding protein 3 like. (544 aa)
DAB2DAB adaptor protein 2. (716 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SKISKI proto-oncogene. (714 aa)
LOC100230282Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (586 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
LOC100224677TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
AXIN2Axin-2 isoform X1. (829 aa)
AXIN1Axin 1. (841 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (781 aa)
CTNNB1Catenin beta 1. (781 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
MYOCDMyocardin. (875 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (501 aa)
SMURF1E3 ubiquitin-protein ligase. (737 aa)
SMAD6SMAD family member 6. (477 aa)
TGFBRAP1CNH domain-containing protein. (863 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (505 aa)
SKILSKI like proto-oncogene. (691 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
HMGA2High mobility group protein HMGI-C isoform X1. (186 aa)
H0ZVJ8_TAEGUc-SKI_SMAD_bind domain-containing protein. (843 aa)
MEF2AMyocyte enhancer factor 2A. (496 aa)
ENSTGUP00000020434annotation not available (505 aa)
MAGI2-2Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1. (136 aa)
LOC115491405Serine/threonine-protein kinase receptor R3 isoform X2. (493 aa)
SMURF2E3 ubiquitin-protein ligase. (777 aa)
ENSTGUP00000023270annotation not available (573 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
ZC3H3Uncharacterized protein. (943 aa)
SMAD3Putative mothers against decapentaplegic 3. (445 aa)
SKOR1SKI family transcriptional corepressor 1. (847 aa)
RANBP3RAN binding protein 3. (588 aa)
H0Z191_TAEGUMothers against decapentaplegic homolog. (343 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (516 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
USP9XUSP domain-containing protein; Belongs to the peptidase C19 family. (2552 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (292 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (370 aa)
SNW1SNW domain containing 1. (538 aa)
ENSTGUP00000031898annotation not available (641 aa)
SMAD4SMAD family member 4. (514 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ENSTGUP00000034670annotation not available (523 aa)
INTS8Integrator complex subunit 8. (995 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1334 aa)
SAV1Salvador family WW domain containing protein 1. (379 aa)
PURBTranscriptional activator protein Pur-beta. (365 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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