STRINGSTRING
SLC26A6 SLC26A6 PKD2 PKD2 AREG AREG EEF2K EEF2K PDE2A PDE2A BCKDHB BCKDHB RAP1A-2 RAP1A-2 P2RX5 P2RX5 RAPGEF1 RAPGEF1 WT1 WT1 LOC100227551 LOC100227551 P2RX6 P2RX6 AKAP6 AKAP6 P2RX4 P2RX4 SLC26A3 SLC26A3 PANX1 PANX1 CFTR CFTR GATA1 GATA1 KCNQ1 KCNQ1 HCN3 HCN3 H0ZR32_TAEGU H0ZR32_TAEGU LOC115491737 LOC115491737 CYP1B1 CYP1B1 LOC115492697 LOC115492697 LOC115491504 LOC115491504 RAPGEF2 RAPGEF2 CARM1 CARM1 AANAT AANAT AQP8 AQP8 NT5E NT5E NDUFS4 NDUFS4 RAP1B RAP1B HCN1 HCN1 AQP1 AQP1 HCN4-2 HCN4-2 ENSTGUP00000033742 ENSTGUP00000033742 P2RY12 P2RY12 ABCC9 ABCC9 P2RX1 P2RX1 P2RX3 P2RX3 IGFBP5 IGFBP5 H0ZI74_TAEGU H0ZI74_TAEGU RAP1A RAP1A KDM1A KDM1A HCN2 HCN2 CRHBP CRHBP HCN4 HCN4 DUOX2 DUOX2 INPP5K INPP5K AQP8-2 AQP8-2 PCK1 PCK1 KCNJ11 KCNJ11 LOC100220528 LOC100220528 EZR EZR HSP90B1 HSP90B1 AKAP7 AKAP7 RFC3 RFC3 DGKQ DGKQ BSG BSG PPARGC1B PPARGC1B CIB2 CIB2 PIK3CG PIK3CG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC26A6Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (735 aa)
PKD2Uncharacterized protein. (903 aa)
AREGAmphiregulin. (195 aa)
EEF2KEukaryotic elongation factor 2 kinase. (736 aa)
PDE2APhosphodiesterase. (949 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (375 aa)
RAP1A-2Ras-related protein Rap-1A. (184 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (438 aa)
RAPGEF1Uncharacterized protein. (1232 aa)
WT1WT1 transcription factor. (414 aa)
LOC100227551Uncharacterized protein. (186 aa)
P2RX6Purinergic receptor P2X 6. (541 aa)
AKAP6A-kinase anchoring protein 6. (2302 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (781 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (430 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
GATA1Erythroid transcription factor. (386 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (691 aa)
HCN3Cyclic nucleotide-binding domain-containing protein. (999 aa)
H0ZR32_TAEGUUncharacterized protein; Belongs to the potassium channel family. (510 aa)
LOC115491737Histone-arginine methyltransferase CARM1. (850 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
LOC115492697Uncharacterized LOC115492697. (573 aa)
LOC115491504Cyclic nucleotide-binding domain-containing protein. (932 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1804 aa)
CARM1LOW QUALITY PROTEIN: histone-arginine methyltransferase CARM1. (581 aa)
AANATAralkylamine N-acetyltransferase. (201 aa)
AQP8Aquaporin 8. (180 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (578 aa)
NDUFS4Putative NADH dehydrogenase Fe-S protein 4. (171 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (597 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
HCN4-2Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1216 aa)
ENSTGUP00000033742annotation not available (1045 aa)
P2RY12Purinergic receptor P2Y12. (339 aa)
ABCC9Uncharacterized protein. (1574 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
P2RX3Purinergic receptor P2X 3. (774 aa)
IGFBP5Insulin like growth factor binding protein 5. (269 aa)
H0ZI74_TAEGUAKAP7_NLS domain-containing protein. (671 aa)
RAP1AUncharacterized protein. (184 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (850 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (919 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (330 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (659 aa)
DUOX2Dual oxidase 2. (1517 aa)
INPP5KIPPc domain-containing protein. (475 aa)
AQP8-2Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (87 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (401 aa)
LOC100220528Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (171 aa)
EZREzrin. (586 aa)
HSP90B1HATPase_c domain-containing protein. (794 aa)
AKAP7A-kinase anchoring protein 7. (407 aa)
RFC3Replication factor C subunit 3. (356 aa)
DGKQDiacylglycerol kinase. (938 aa)
BSGBasigin (Ok blood group). (345 aa)
PPARGC1BPPARG coactivator 1 beta. (988 aa)
CIB2Uncharacterized protein. (192 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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