STRINGSTRING
THY1 THY1 CACNB4 CACNB4 PRAM1 PRAM1 CD247 CD247 MALT1 MALT1 ENSTGUP00000032834 ENSTGUP00000032834 ENSTGUP00000031809 ENSTGUP00000031809 PTPN6 PTPN6 ZC3H12A ZC3H12A CRKL CRKL PTPRC PTPRC PSEN1 PSEN1 TXK TXK RBCK1 RBCK1 TNFRSF21 TNFRSF21 TMEM269 TMEM269 ENSTGUP00000024330 ENSTGUP00000024330 TRAF6 TRAF6 ENSTGUP00000022855 ENSTGUP00000022855 LOC105760451 LOC105760451 SKAP1 SKAP1 THEMIS THEMIS LOC100222362 LOC100222362 ENSTGUP00000020196 ENSTGUP00000020196 CD276 CD276 NFKBID NFKBID KHDRBS1 KHDRBS1 CD28 CD28 EIF2B4 EIF2B4 HHLA2 HHLA2 VTCN1 VTCN1 EIF2B2 EIF2B2 RIPK2 RIPK2 EIF2B5 EIF2B5 SPPL3 SPPL3 FYB2 FYB2 TEC TEC EIF2B3 EIF2B3 RC3H2 RC3H2 LOC115496886 LOC115496886 EIF2B1 EIF2B1 PLCG1 PLCG1 PLCG2 PLCG2 DENND1B DENND1B RC3H1 RC3H1 RFTN1 RFTN1 FYB1 FYB1 GATA3 GATA3 STOML2 STOML2 ITK ITK LOC100223311 LOC100223311 ZAP70 ZAP70
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THY1Thy-1 cell surface antigen. (241 aa)
CACNB4SH3 domain-containing protein. (478 aa)
PRAM1hSH3 domain-containing protein. (415 aa)
CD247CD247 molecule. (158 aa)
MALT1MALT1 paracaspase. (878 aa)
ENSTGUP00000032834annotation not available (233 aa)
ENSTGUP00000031809annotation not available (496 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (840 aa)
ZC3H12AC3H1-type domain-containing protein. (609 aa)
CRKLUncharacterized protein. (303 aa)
PTPRCUncharacterized protein. (1194 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
TXKTXK tyrosine kinase. (546 aa)
RBCK1RanBP-type and C3HC4-type zinc finger-containing protein 1. (333 aa)
TNFRSF21TNF receptor superfamily member 21. (658 aa)
TMEM269Transmembrane protein 269. (321 aa)
ENSTGUP00000024330annotation not available (343 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
ENSTGUP00000022855annotation not available (584 aa)
LOC105760451CASPASE_P20 domain-containing protein. (760 aa)
SKAP1PH domain-containing protein. (361 aa)
THEMISThymocyte selection associated. (683 aa)
LOC100222362Phosphoinositide phospholipase C. (1311 aa)
ENSTGUP000000201961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1. (1281 aa)
CD276Ig-like domain-containing protein. (420 aa)
NFKBIDNF-kappa-B inhibitor delta. (391 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (359 aa)
CD28CD28 molecule. (222 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (728 aa)
HHLA2HERV-H LTR-associating 2. (351 aa)
VTCN1Uncharacterized protein. (242 aa)
EIF2B2Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (363 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (553 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (707 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
FYB2hSH3 domain-containing protein. (715 aa)
TECTyrosine-protein kinase. (630 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (452 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
LOC115496886Protein kinase domain-containing protein. (554 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (302 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1282 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
DENND1BDENN domain containing 1B. (789 aa)
RC3H1Uncharacterized protein. (1124 aa)
RFTN1Raftlin, lipid raft linker 1. (602 aa)
FYB1FYN binding protein 1. (804 aa)
GATA3GATA binding protein 3. (443 aa)
STOML2Stomatin like 2. (334 aa)
ITKTyrosine-protein kinase. (631 aa)
LOC100223311Uncharacterized protein. (742 aa)
ZAP70Tyrosine-protein kinase. (609 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.