STRINGSTRING
CHUK CHUK CAPN3 CAPN3 ENSTGUP00000031580 ENSTGUP00000031580 DHX33 DHX33 DHX9 DHX9 DDX58 DDX58 SMO SMO TRAF2 TRAF2 ENSTGUP00000031473 ENSTGUP00000031473 NTS NTS JMY JMY IL1B IL1B TRAF5 TRAF5 PRKCZ PRKCZ LOC100231082 LOC100231082 AR AR IL6 IL6 EDA EDA CIB1 CIB1 APP APP RPS6KA5 RPS6KA5 ARHGEF2 ARHGEF2 CAV1 CAV1 TNFRSF11A TNFRSF11A LOC100231082-2 LOC100231082-2 LOC115497877 LOC115497877 ARID5B ARID5B ADCY1 ADCY1 CD40 CD40 ESR1 ESR1 COPS5 COPS5 H0ZNG1_TAEGU H0ZNG1_TAEGU RIPK2 RIPK2 ARHGEF5 ARHGEF5 RWDD1 RWDD1 PSMA6 PSMA6 ABRA ABRA TRAPPC9 TRAPPC9 LRP6 LRP6 ANKRD42 ANKRD42 LPAR5 LPAR5 RELT RELT PINK1 PINK1 CX3CR1 CX3CR1 TRADD TRADD FLOT1 FLOT1 MTPN MTPN TERF2IP TERF2IP TIRAP TIRAP LOC100223835 LOC100223835 NDP NDP LRP8 LRP8 LOC105760451 LOC105760451 ENSTGUP00000022855 ENSTGUP00000022855 ZC4H2 ZC4H2 IL18R1 IL18R1 TRAF6 TRAF6 NEUROD1 NEUROD1 ENSTGUP00000024330 ENSTGUP00000024330 LOC115496138 LOC115496138 CRTC1 CRTC1 TNFSF11 TNFSF11 ADCY8 ADCY8 JUP JUP LRP5 LRP5 RBCK1 RBCK1 NOD1 NOD1 DDRGK1 DDRGK1 MAVS MAVS IRAK2 IRAK2 CAV3 CAV3 SMARCB1 SMARCB1 CLUL1 CLUL1 TRIM8 TRIM8 EP300 EP300 CYTL1 CYTL1 ROR1-2 ROR1-2 IL18RAP IL18RAP PPRC1 PPRC1 NFAM1 NFAM1 PLPP3 PLPP3 IL1RAP IL1RAP TFDP1 TFDP1 EIF2AK2 EIF2AK2 SLCO3A1 SLCO3A1 KIT KIT WHAMM WHAMM RNF220 RNF220 BUD31 BUD31 CLU CLU IL10 IL10 TAF12 TAF12 MYOCD MYOCD RNF25 RNF25 IKBKB IKBKB PPARGC1B PPARGC1B LOC100223311 LOC100223311 TRIM14 TRIM14 MBTPS2 MBTPS2 IHH IHH TRIM32 TRIM32 STK36 STK36 EDA2R EDA2R SAV1 SAV1 RIPK4 RIPK4 CTNNB1 CTNNB1 LOC115493114 LOC115493114 PRKCI PRKCI RAB7B RAB7B CRTC2 CRTC2 CAT CAT EDN1 EDN1 PPARGC1A PPARGC1A FZD4 FZD4 CX3CL1 CX3CL1 KDM1A KDM1A LOC100232398 LOC100232398 ENSTGUP00000033975 ENSTGUP00000033975 TRIM37 TRIM37 FLOT2 FLOT2 CARD9 CARD9 TRAF1 TRAF1 LOC115496886 LOC115496886 TLR3 TLR3 ROR1 ROR1 TNFRSF19 TNFRSF19 RIPK1 RIPK1 MALT1 MALT1 CARD11 CARD11 LOC115497975 LOC115497975 DDR2 DDR2 SRF SRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHUKProtein kinase domain-containing protein. (762 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (809 aa)
ENSTGUP00000031580annotation not available (272 aa)
DHX33DEAH-box helicase 33. (669 aa)
DHX9Uncharacterized protein. (1240 aa)
DDX58DExD/H-box helicase 58. (958 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (778 aa)
TRAF2TNF receptor-associated factor. (486 aa)
ENSTGUP00000031473annotation not available (499 aa)
NTSUncharacterized protein. (164 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (908 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (299 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (555 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
LOC100231082Uncharacterized protein. (873 aa)
ARAndrogen receptor. (684 aa)
IL6Interleukin 6. (221 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (239 aa)
CIB1Calcium and integrin binding 1. (213 aa)
APPAmyloid beta precursor protein. (797 aa)
RPS6KA5Ribosomal protein S6 kinase. (784 aa)
ARHGEF2Rho guanine nucleotide exchange factor 2 isoform X3. (1180 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TNFRSF11ATNFR-Cys domain-containing protein. (663 aa)
LOC100231082-2Discoidin domain-containing receptor 2-like. (873 aa)
LOC115497877OX-2 membrane glycoprotein-like. (407 aa)
ARID5BAT-rich interaction domain 5B. (1195 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
CD40CD40 molecule. (280 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (621 aa)
COPS5MPN domain-containing protein. (339 aa)
H0ZNG1_TAEGUCostars domain-containing protein. (203 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (553 aa)
ARHGEF5Uncharacterized protein. (1775 aa)
RWDD1RWD domain containing 1. (240 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
ABRAActin binding Rho activating protein. (452 aa)
TRAPPC9Trafficking protein particle complex 9. (1151 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1612 aa)
ANKRD42Ankyrin repeat domain 42. (519 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (343 aa)
RELTUncharacterized protein. (451 aa)
PINK1PTEN induced kinase 1. (515 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (353 aa)
TRADDTNFRSF1A associated via death domain. (409 aa)
FLOT1Flotillin-1. (451 aa)
MTPNMyotrophin. (286 aa)
TERF2IPTERF2 interacting protein. (336 aa)
TIRAPTIR domain containing adaptor protein. (410 aa)
LOC100223835E3 ubiquitin-protein ligase TRIM62. (473 aa)
NDPCTCK domain-containing protein. (148 aa)
LRP8LDL receptor related protein 8. (964 aa)
LOC105760451CASPASE_P20 domain-containing protein. (760 aa)
ENSTGUP00000022855annotation not available (584 aa)
ZC4H2Zinc finger C4H2-type containing. (229 aa)
IL18R1TIR domain-containing protein. (565 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
NEUROD1Neurogenic differentiation factor 1 isoform X1. (363 aa)
ENSTGUP00000024330annotation not available (343 aa)
LOC115496138Cystathionine gamma-lyase-like. (665 aa)
CRTC1CREB regulated transcription coactivator 1. (620 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (317 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1319 aa)
JUPJunction plakoglobin. (764 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1595 aa)
RBCK1RanBP-type and C3HC4-type zinc finger-containing protein 1. (333 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (951 aa)
DDRGK1DDRGK domain containing 1. (298 aa)
MAVSCARD_2 domain-containing protein. (627 aa)
IRAK2Protein kinase domain-containing protein. (656 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (386 aa)
CLUL1Clusterin; Belongs to the clusterin family. (461 aa)
TRIM8Tripartite motif containing 8. (545 aa)
EP300E1A binding protein p300. (2445 aa)
CYTL1Cytokine like 1. (133 aa)
ROR1-2Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa)
IL18RAPInterleukin 18 receptor accessory protein. (587 aa)
PPRC1RRM domain-containing protein. (1336 aa)
NFAM1Uncharacterized protein. (269 aa)
PLPP3acidPPc domain-containing protein. (313 aa)
IL1RAPUncharacterized protein. (691 aa)
TFDP1Transcription factor. (412 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (512 aa)
SLCO3A1Solute carrier organic anion transporter family member. (708 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
WHAMMWASP homolog associated with actin, golgi membranes and microtubules. (794 aa)
RNF220Ring finger protein 220. (591 aa)
BUD31Uncharacterized protein. (144 aa)
CLUClusterin. (525 aa)
IL10Interleukin 10. (165 aa)
TAF12TATA-box binding protein associated factor 12. (357 aa)
MYOCDMyocardin. (875 aa)
RNF25Ring finger protein 25. (506 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
PPARGC1BPPARG coactivator 1 beta. (988 aa)
LOC100223311Uncharacterized protein. (742 aa)
TRIM14Tripartite motif containing 14. (508 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (503 aa)
IHHIndian hedgehog signaling molecule. (408 aa)
TRIM32Tripartite motif containing 32. (647 aa)
STK36Serine/threonine kinase 36. (1065 aa)
EDA2REctodysplasin A2 receptor. (495 aa)
SAV1Salvador family WW domain containing protein 1. (379 aa)
RIPK4Receptor interacting serine/threonine kinase 4. (789 aa)
CTNNB1Catenin beta 1. (781 aa)
LOC115493114Flotillin-1-like. (451 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (470 aa)
RAB7BRAB7B, member RAS oncogene family. (254 aa)
CRTC2CREB-regulated transcription coactivator 2 isoform X1. (754 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (547 aa)
EDN1Endothelin 1. (202 aa)
PPARGC1APPARG coactivator 1 alpha. (807 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
CX3CL1Uncharacterized protein. (429 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (850 aa)
LOC100232398Cystathionine gamma-lyase. (440 aa)
ENSTGUP00000033975annotation not available (497 aa)
TRIM37Uncharacterized protein. (1068 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
CARD9CARD domain-containing protein. (206 aa)
TRAF1TNF receptor-associated factor. (553 aa)
LOC115496886Protein kinase domain-containing protein. (554 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (896 aa)
ROR1Inactive tyrosine-protein kinase transmembrane receptor ROR1-like. (940 aa)
TNFRSF19TNF receptor superfamily member 19. (409 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
MALT1MALT1 paracaspase. (878 aa)
CARD11Caspase recruitment domain family member 11. (1167 aa)
LOC115497975Tripartite motif containing 62. (475 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (1179 aa)
SRFSerum response factor. (485 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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