STRINGSTRING
ITGB1BP1 ITGB1BP1 TTC36 TTC36 GTPBP4 GTPBP4 ZNF593 ZNF593 IL10 IL10 KDM1A KDM1A ILRUN ILRUN SMO SMO DAB2 DAB2 FRMD7 FRMD7 EFHB EFHB TNKS TNKS ERCC4 ERCC4 PSME3IP1 PSME3IP1 ATP2A2 ATP2A2 ZNF462 ZNF462 TEX14 TEX14 DHRS7B DHRS7B TFIP11 TFIP11 CTSZ CTSZ ADNP ADNP MYOD1 MYOD1 BTAF1 BTAF1 WFIKKN2 WFIKKN2 ITGA4 ITGA4 PCSK9 PCSK9 MSX1 MSX1 ARHGAP28 ARHGAP28 MITD1 MITD1 LOC100228000 LOC100228000 ROCK1 ROCK1 CAV3 CAV3 TTBK2 TTBK2 TDG TDG GEMIN2 GEMIN2 DDX11 DDX11 RSF1 RSF1 BAX BAX HMGA2 HMGA2 ENSTGUP00000019413 ENSTGUP00000019413 PDGFB PDGFB FBXW7 FBXW7 ADIPOQ ADIPOQ WAPL WAPL LRRK2 LRRK2 ANKRD33B ANKRD33B STYX STYX ANKRD33 ANKRD33 ENSTGUP00000021490 ENSTGUP00000021490 CRMP1 CRMP1 DISC1 DISC1 SLN SLN ZFPM1 ZFPM1 MEPCE MEPCE BAG2 BAG2 ENSTGUP00000023546 ENSTGUP00000023546 REST REST GATA1 GATA1 FBXW9 FBXW9 ENSTGUP00000025117 ENSTGUP00000025117 PLN PLN NES NES EPB41L5 EPB41L5 PSEN1 PSEN1 CAV1 CAV1 NEK2 NEK2 ATP2A1 ATP2A1 DTNBP1 DTNBP1 LRPAP1 LRPAP1 LOC100224555 LOC100224555 DKK1 DKK1 ENSTGUP00000030494 ENSTGUP00000030494 C9orf72 C9orf72 ENSTGUP00000030827 ENSTGUP00000030827 TFAP4 TFAP4 ENSTGUP00000031580 ENSTGUP00000031580 HAND1 HAND1 PEX14 PEX14 LEF1 LEF1 SRI SRI TTBK1 TTBK1 ENSTGUP00000033543 ENSTGUP00000033543 WFIKKN1 WFIKKN1 PIN1 PIN1 MAP2 MAP2 ENSTGUP00000035714 ENSTGUP00000035714 SYMPK SYMPK LOC100228958 LOC100228958
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
TTC36Tetratricopeptide repeat domain 36. (185 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (631 aa)
ZNF593Zinc finger protein 593. (133 aa)
IL10Interleukin 10. (165 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (850 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (778 aa)
DAB2DAB adaptor protein 2. (716 aa)
FRMD7FERM domain containing 7. (702 aa)
EFHBEF-hand domain family member B. (584 aa)
TNKSPoly [ADP-ribose] polymerase. (1266 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (901 aa)
PSME3IP1Family with sequence similarity 192 member A. (255 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1043 aa)
ZNF462Zinc finger protein 462. (2475 aa)
TEX14Uncharacterized protein. (1462 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Belongs to the TFP11/STIP family. (827 aa)
CTSZPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (300 aa)
ADNPActivity-dependent neuroprotector homeobox protein isoform X1. (1226 aa)
MYOD1Myogenic factor. (294 aa)
BTAF1B-TFIID TATA-box binding protein associated factor 1. (1844 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (570 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1024 aa)
PCSK9Peptidase_S8 domain-containing protein; Belongs to the peptidase S8 family. (663 aa)
MSX1Msh homeobox 1. (291 aa)
ARHGAP28Rho GTPase activating protein 28. (605 aa)
MITD1Microtubule interacting and trafficking domain containing 1. (335 aa)
LOC100228000Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
ROCK1Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1358 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TTBK2Tau tubulin kinase 2. (1248 aa)
TDGThymine DNA glycosylase. (402 aa)
GEMIN2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (263 aa)
DDX11DEAD/H-box helicase 11. (894 aa)
RSF1Remodeling and spacing factor 1. (1430 aa)
BAXBCL2 associated X, apoptosis regulator. (225 aa)
HMGA2High mobility group protein HMGI-C isoform X1. (186 aa)
ENSTGUP00000019413annotation not available (508 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (278 aa)
FBXW7F-box and WD repeat domain containing 7. (745 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (245 aa)
WAPLWAPL cohesin release factor. (1434 aa)
LRRK2Leucine rich repeat kinase 2. (2509 aa)
ANKRD33BAnkyrin repeat domain 33B. (519 aa)
STYXSerine/threonine/tyrosine interacting protein. (230 aa)
ANKRD33Photoreceptor ankyrin repeat protein. (261 aa)
ENSTGUP00000021490annotation not available (853 aa)
CRMP1Collapsin response mediator protein 1. (683 aa)
DISC1DISC1 scaffold protein. (852 aa)
SLNSarcolipin. (31 aa)
ZFPM1Uncharacterized protein. (1560 aa)
MEPCEMethylphosphate capping enzyme. (547 aa)
BAG2Putative BCL2-associated athanogene 2. (224 aa)
ENSTGUP00000023546annotation not available (228 aa)
RESTRE1 silencing transcription factor. (893 aa)
GATA1Erythroid transcription factor. (386 aa)
FBXW9Uncharacterized protein. (526 aa)
ENSTGUP00000025117annotation not available (277 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
NESIF rod domain-containing protein; Belongs to the intermediate filament family. (1641 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (766 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
NEK2NIMA related kinase 2. (497 aa)
ATP2A1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1. (1187 aa)
DTNBP1Dystrobrevin binding protein 1. (351 aa)
LRPAP1Uncharacterized protein. (473 aa)
LOC100224555Activity dependent neuroprotector homeobox. (1226 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (263 aa)
ENSTGUP00000030494annotation not available (491 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
ENSTGUP00000030827annotation not available (64 aa)
TFAP4Transcription factor AP-4. (385 aa)
ENSTGUP00000031580annotation not available (272 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (202 aa)
PEX14Peroxisomal biogenesis factor 14. (378 aa)
LEF1Lymphoid enhancer binding factor 1. (412 aa)
SRIPutative sorcin transcript variant 1. (323 aa)
TTBK1Tau tubulin kinase 1. (1418 aa)
ENSTGUP00000033543annotation not available (434 aa)
WFIKKN1WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1. (571 aa)
PIN1Peptidylprolyl cis/trans isomerase, NIMA-interacting 1. (156 aa)
MAP2Microtubule-associated protein. (1946 aa)
ENSTGUP00000035714annotation not available (167 aa)
SYMPKSymplekin. (1106 aa)
LOC100228958WD_REPEATS_REGION domain-containing protein. (783 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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