STRINGSTRING
HMCES HMCES ENSTGUP00000027497 ENSTGUP00000027497 TFRC TFRC H0Z9C2_TAEGU H0Z9C2_TAEGU BST1 BST1 NLRP3 NLRP3 RASGRP1 RASGRP1 LOC101232862 LOC101232862 ABL1 ABL1 SART1 SART1 LOC100223529 LOC100223529 TNFSF11 TNFSF11 LOC115492780 LOC115492780 ENSTGUP00000024522 ENSTGUP00000024522 ENSTGUP00000024453 ENSTGUP00000024453 EFNB2 EFNB2 ENSTGUP00000024289 ENSTGUP00000024289 H0ZWI5_TAEGU H0ZWI5_TAEGU TRAF6 TRAF6 ENSTGUP00000023651 ENSTGUP00000023651 H1A280_TAEGU H1A280_TAEGU TBX21 TBX21 H0ZXL7_TAEGU H0ZXL7_TAEGU LOC105760451 LOC105760451 SOCS5 SOCS5 ENSTGUP00000022250 ENSTGUP00000022250 MLH1 MLH1 INPP5D INPP5D H0ZIT4_TAEGU H0ZIT4_TAEGU TIRAP TIRAP CD74 CD74 H1A352_TAEGU H1A352_TAEGU LOC100218309 LOC100218309 AMBRA1 AMBRA1 ENSTGUP00000019351 ENSTGUP00000019351 ENSTGUP00000019236 ENSTGUP00000019236 ABL2 ABL2 CD276 CD276 NFKBID NFKBID LOC100231564 LOC100231564 LOC100229282 LOC100229282 CD28 CD28 H1A3U4_TAEGU H1A3U4_TAEGU ENSTGUP00000016400 ENSTGUP00000016400 STAT6 STAT6 HHLA2 HHLA2 VTCN1 VTCN1 CD86 CD86 ZBTB1 ZBTB1 FAM49B FAM49B AKIRIN2 AKIRIN2 PPP2R3C PPP2R3C RIPK2 RIPK2 SLC7A1 SLC7A1 IL7 IL7 MYB MYB TOX TOX GPR183 GPR183 TNFSF13B TNFSF13B GPAM GPAM MDK MDK HSPD1 HSPD1 CAV3 CAV3 KMT5B KMT5B TNFRSF13C TNFRSF13C LOC100232284 LOC100232284 NCK2 NCK2 BCL6 BCL6 IGF2 IGF2 LAMP1 LAMP1 PCID2 PCID2 PMS2 PMS2 PTPRC PTPRC BLOC1S6 BLOC1S6 LOC100219073 LOC100219073 LOC115496886 LOC115496886 H0Z8Z3_TAEGU H0Z8Z3_TAEGU MORN5 MORN5 LOC100219822 LOC100219822 H0Z7I6_TAEGU H0Z7I6_TAEGU H0Z7I3_TAEGU H0Z7I3_TAEGU ZNF335 ZNF335 CD40 CD40 DOCK8 DOCK8 MSH6 MSH6 MSH2 MSH2 SASH3 SASH3 CD274 CD274 ATAD5 ATAD5 SOCS1 SOCS1 B2M B2M VSIR VSIR TGFBR2 TGFBR2 IL1B IL1B H0YXS2_TAEGU H0YXS2_TAEGU SOX13 SOX13 IL6 IL6 HLX HLX CCR7 CCR7 GATA3 GATA3 IL7R IL7R H0YTY7_TAEGU H0YTY7_TAEGU LCK LCK IL10 IL10 SYK SYK THY1 THY1 ZAP70 ZAP70 IL18 IL18 LOC100223311 LOC100223311 ZBTB16 ZBTB16 ANXA1 ANXA1 IHH IHH ENSTGUP00000037897 ENSTGUP00000037897 ENSTGUP00000037877 ENSTGUP00000037877 CLCF1 CLCF1 EXOSC3 EXOSC3 GAS6 GAS6 LOC115496603 LOC115496603 RHOH RHOH ENSTGUP00000036930 ENSTGUP00000036930 CD38 CD38 LGALS1 LGALS1 TP53BP1 TP53BP1 LOC115493248 LOC115493248 XBP1 XBP1 TNFRSF4 TNFRSF4 IL21 IL21 FADD FADD EXOSC6 EXOSC6 CD83 CD83 ENSTGUP00000034391 ENSTGUP00000034391 ENSTGUP00000034101 ENSTGUP00000034101 LOC100221605 LOC100221605 PELI1 PELI1 ENSTGUP00000033866 ENSTGUP00000033866 LOC100221316 LOC100221316 IL15 IL15 DUSP10 DUSP10 MALT1 MALT1 CARD11 CARD11 LEF1 LEF1 IL6ST IL6ST ENSTGUP00000031809 ENSTGUP00000031809 KMT5C KMT5C ENSTGUP00000030707 ENSTGUP00000030707 CCL19 CCL19 ENSTGUP00000029638 ENSTGUP00000029638 ENSTGUP00000028817 ENSTGUP00000028817 NSD2 NSD2 BLOC1S3 BLOC1S3 LEP LEP CAV1 CAV1 CBFB CBFB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HMCESAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (335 aa)
ENSTGUP00000027497annotation not available (154 aa)
TFRCTransferrin receptor. (776 aa)
H0Z9C2_TAEGUUncharacterized protein. (587 aa)
BST1Bone marrow stromal cell antigen 1. (316 aa)
NLRP3NACHT domain-containing protein. (901 aa)
RASGRP1RAS guanyl releasing protein 1. (792 aa)
LOC101232862RHD_dimer domain-containing protein. (700 aa)
ABL1Tyrosine-protein kinase. (1139 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (797 aa)
LOC100223529RHD domain-containing protein. (925 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (317 aa)
LOC115492780ephrin-B3-like. (259 aa)
ENSTGUP00000024522annotation not available (197 aa)
ENSTGUP00000024453HLA class II histocompatibility antigen, DM beta chain-like. (551 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (364 aa)
ENSTGUP00000024289Basic proline-rich protein-like. (206 aa)
H0ZWI5_TAEGUIg-like domain-containing protein. (762 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
ENSTGUP00000023651annotation not available (927 aa)
H1A280_TAEGUIg-like domain-containing protein. (298 aa)
TBX21T-box transcription factor 21. (599 aa)
H0ZXL7_TAEGUIg-like domain-containing protein. (395 aa)
LOC105760451CASPASE_P20 domain-containing protein. (760 aa)
SOCS5Suppressor of cytokine signaling 5. (535 aa)
ENSTGUP00000022250annotation not available (245 aa)
MLH1MutL homolog 1. (749 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1214 aa)
H0ZIT4_TAEGUUncharacterized protein. (954 aa)
TIRAPTIR domain containing adaptor protein. (410 aa)
CD74Uncharacterized protein. (289 aa)
H1A352_TAEGUUncharacterized protein. (360 aa)
LOC100218309Ig-like domain-containing protein. (333 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1299 aa)
ENSTGUP00000019351annotation not available (381 aa)
ENSTGUP00000019236annotation not available (293 aa)
ABL2Tyrosine-protein kinase. (1160 aa)
CD276Ig-like domain-containing protein. (420 aa)
NFKBIDNF-kappa-B inhibitor delta. (391 aa)
LOC100231564Ig-like domain-containing protein. (286 aa)
LOC100229282Ig-like domain-containing protein. (228 aa)
CD28CD28 molecule. (222 aa)
H1A3U4_TAEGUIg-like domain-containing protein. (179 aa)
ENSTGUP00000016400annotation not available (274 aa)
STAT6Signal transducer and activator of transcription 6. (932 aa)
HHLA2HERV-H LTR-associating 2. (351 aa)
VTCN1Uncharacterized protein. (242 aa)
CD86CD86 molecule. (302 aa)
ZBTB1Zinc finger and BTB domain containing 1. (711 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
AKIRIN2Akirin 2. (193 aa)
PPP2R3CEF-hand_13 domain-containing protein. (450 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (553 aa)
SLC7A1AA_permease_C domain-containing protein. (624 aa)
IL7Uncharacterized protein. (179 aa)
MYBMYB proto-oncogene, transcription factor. (764 aa)
TOXThymocyte selection associated high mobility group box. (539 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (381 aa)
TNFSF13BTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (288 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (847 aa)
MDKMidkine. (139 aa)
HSPD1Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (573 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
KMT5BLysine methyltransferase 5B. (850 aa)
TNFRSF13CUncharacterized protein. (211 aa)
LOC100232284IGv domain-containing protein. (218 aa)
NCK2NCK adaptor protein 2. (380 aa)
BCL6BCL6 transcription repressor. (729 aa)
IGF2IlGF domain-containing protein. (225 aa)
LAMP1Lysosomal associated membrane protein 1. (415 aa)
PCID2PCI domain containing 2. (400 aa)
PMS2PMS1 homolog 2, mismatch repair system component. (870 aa)
PTPRCUncharacterized protein. (1194 aa)
BLOC1S6Biogenesis of lysosomal organelles complex 1 subunit 6. (165 aa)
LOC100219073Uncharacterized protein. (445 aa)
LOC115496886Protein kinase domain-containing protein. (554 aa)
H0Z8Z3_TAEGUUncharacterized protein; Belongs to the peptidase S9B family. (672 aa)
MORN5MORN repeat containing 5. (172 aa)
LOC100219822ZP domain-containing protein. (459 aa)
H0Z7I6_TAEGUUncharacterized protein. (461 aa)
H0Z7I3_TAEGUUncharacterized protein. (403 aa)
ZNF335Zinc finger protein 335. (1457 aa)
CD40CD40 molecule. (280 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2099 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1262 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (936 aa)
SASH3Uncharacterized protein. (568 aa)
CD274CD274 molecule. (360 aa)
ATAD5ATPase family AAA domain containing 5. (1827 aa)
SOCS1Suppressor of cytokine signaling 1. (207 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (170 aa)
VSIRIg-like domain-containing protein. (310 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (299 aa)
H0YXS2_TAEGUIg-like domain-containing protein. (198 aa)
SOX13SRY-box transcription factor 13. (555 aa)
IL6Interleukin 6. (221 aa)
HLXH2.0 like homeobox. (425 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)
GATA3GATA binding protein 3. (443 aa)
IL7RInterleukin 7 receptor. (460 aa)
H0YTY7_TAEGUGalectin. (199 aa)
LCKProtein kinase domain-containing protein. (513 aa)
IL10Interleukin 10. (165 aa)
SYKTyrosine-protein kinase. (668 aa)
THY1Thy-1 cell surface antigen. (241 aa)
ZAP70Tyrosine-protein kinase. (609 aa)
IL18Interleukin-18. (192 aa)
LOC100223311Uncharacterized protein. (742 aa)
ZBTB16Zinc finger and BTB domain containing 16. (644 aa)
ANXA1Annexin. (364 aa)
IHHIndian hedgehog signaling molecule. (408 aa)
ENSTGUP00000037897annotation not available (399 aa)
ENSTGUP00000037877annotation not available (494 aa)
CLCF1Cardiotrophin like cytokine factor 1. (257 aa)
EXOSC3KH_dom_type_1 domain-containing protein. (384 aa)
GAS6Growth arrest specific 6. (704 aa)
LOC115496603Zona pellucida sperm-binding protein 3-like. (426 aa)
RHOHRas homolog family member H. (191 aa)
ENSTGUP00000036930annotation not available (277 aa)
CD38CD38 molecule. (506 aa)
LGALS1Galectin. (136 aa)
TP53BP1Tumor protein p53 binding protein 1. (1923 aa)
LOC115493248HLA class II histocompatibility antigen, DR alpha chain-like. (426 aa)
XBP1X-box binding protein 1. (260 aa)
TNFRSF4Uncharacterized protein. (319 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (194 aa)
FADDFas associated via death domain. (221 aa)
EXOSC6Exosome complex component MTR3. (274 aa)
CD83CD83 antigen. (246 aa)
ENSTGUP00000034391Mucin-2-like. (483 aa)
ENSTGUP00000034101annotation not available (743 aa)
LOC100221605Programmed cell death 1 ligand 2. (322 aa)
PELI1Uncharacterized protein. (460 aa)
ENSTGUP00000033866annotation not available (454 aa)
LOC100221316Class II histocompatibility antigen, B-L beta chain-like. (333 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (199 aa)
DUSP10Dual specificity phosphatase 10. (481 aa)
MALT1MALT1 paracaspase. (878 aa)
CARD11Caspase recruitment domain family member 11. (1167 aa)
LEF1Lymphoid enhancer binding factor 1. (412 aa)
IL6STInterleukin 6 signal transducer. (921 aa)
ENSTGUP00000031809annotation not available (496 aa)
KMT5CLysine methyltransferase 5C. (486 aa)
ENSTGUP00000030707annotation not available (313 aa)
CCL19C-C motif chemokine ligand 19. (152 aa)
ENSTGUP00000029638annotation not available (280 aa)
ENSTGUP00000028817annotation not available (329 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1428 aa)
BLOC1S3Uncharacterized protein. (264 aa)
LEPTaeniopygia guttata leptin (LEP), mRNA. (168 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CBFBCore-binding factor subunit beta. (408 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (22%) [HD]