31 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	ARHGEF10	Rho guanine nucleotide exchange factor 10. (1353 aa)
	MTOR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (1322 aa)
	LOC100226560	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (289 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
	TSC1	Uncharacterized protein. (1175 aa)
	SERPINF2	Serpin family F member 2; Belongs to the serpin family. (516 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (501 aa)
	LOC115497772	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (320 aa)
	NF2	Neurofibromin 2. (595 aa)
	CCN2	Cellular communication network factor 2. (347 aa)
	ARHGEF5	Uncharacterized protein. (1775 aa)
	GPR65	G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (435 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	ROCK2	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1483 aa)
	EPHA1	EPH receptor A1. (962 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
	EVL	WH1 domain-containing protein. (423 aa)
	TESK1	Testis associated actin remodelling kinase 1. (692 aa)
	APOA1	Uncharacterized protein. (264 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	LOC100230978	FERM domain-containing protein. (660 aa)
	ARHGEF10L	Uncharacterized protein. (1357 aa)
	LOC115491504	Cyclic nucleotide-binding domain-containing protein. (932 aa)
	BAG4	Uncharacterized protein. (340 aa)
	LOC115498434	Protein S100-A10 isoform X2. (279 aa)
	ENSTGUP00000033254	annotation not available (279 aa)
	LIMCH1	LIM and calponin homology domains-containing protein 1 isoform X1. (1746 aa)
	ENSTGUP00000033742	annotation not available (1045 aa)
	CDC42	Cell division cycle 42. (302 aa)
	PPM1E	Protein phosphatase, Mg2+/Mn2+ dependent 1E. (844 aa)
	MYOC	Myocilin. (521 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF10	CDC42	ENSTGUP00000030395	ENSTGUP00000036310	Rho guanine nucleotide exchange factor 10.	Cell division cycle 42.	0.401
ARHGEF5	CDC42	ENSTGUP00000012254	ENSTGUP00000036310	Uncharacterized protein.	Cell division cycle 42.	0.515
CDC42	ARHGEF10	ENSTGUP00000036310	ENSTGUP00000030395	Cell division cycle 42.	Rho guanine nucleotide exchange factor 10.	0.401
CDC42	ARHGEF5	ENSTGUP00000036310	ENSTGUP00000012254	Cell division cycle 42.	Uncharacterized protein.	0.515
CDC42	EPHA1	ENSTGUP00000036310	ENSTGUP00000013638	Cell division cycle 42.	EPH receptor A1.	0.576
CDC42	LOC100230978	ENSTGUP00000036310	ENSTGUP00000025196	Cell division cycle 42.	FERM domain-containing protein.	0.614
CDC42	NF2	ENSTGUP00000036310	ENSTGUP00000010812	Cell division cycle 42.	Neurofibromin 2.	0.620
CDC42	ROCK2	ENSTGUP00000036310	ENSTGUP00000013462	Cell division cycle 42.	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.623
ENSTGUP00000033254	MTOR	ENSTGUP00000033254	ENSTGUP00000002370	annotation not available	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.900
ENSTGUP00000033254	TSC1	ENSTGUP00000033254	ENSTGUP00000005424	annotation not available	Uncharacterized protein.	0.857
EPHA1	CDC42	ENSTGUP00000013638	ENSTGUP00000036310	EPH receptor A1.	Cell division cycle 42.	0.576
LOC100226560	WNT11	ENSTGUP00000002757	ENSTGUP00000013965	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.901
LOC100230978	CDC42	ENSTGUP00000025196	ENSTGUP00000036310	FERM domain-containing protein.	Cell division cycle 42.	0.614
LOC100230978	NF2	ENSTGUP00000025196	ENSTGUP00000010812	FERM domain-containing protein.	Neurofibromin 2.	0.901
LOC115497772	LPAR1	ENSTGUP00000008233	ENSTGUP00000022477	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.900
LPAR1	LOC115497772	ENSTGUP00000022477	ENSTGUP00000008233	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.900
MTOR	ENSTGUP00000033254	ENSTGUP00000002370	ENSTGUP00000033254	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	annotation not available	0.900
MTOR	TSC1	ENSTGUP00000002370	ENSTGUP00000005424	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.857
NF2	CDC42	ENSTGUP00000010812	ENSTGUP00000036310	Neurofibromin 2.	Cell division cycle 42.	0.620
NF2	LOC100230978	ENSTGUP00000010812	ENSTGUP00000025196	Neurofibromin 2.	FERM domain-containing protein.	0.901