(6 nodes) Ventricular cardiac muscle cell differentiation network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MEF2C	Myocyte enhancer factor 2C. (244 aa)
	NKX2-5	Homeobox domain-containing protein. (329 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	PITX2	Homeobox protein. (360 aa)
	MYOCD	Myocardin. (875 aa)
	MEF2A	Myocyte enhancer factor 2A. (496 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MEF2A	NKX2-5	ENSTGUP00000019739	ENSTGUP00000030328	Myocyte enhancer factor 2A.	Homeobox domain-containing protein.	0.780
MEF2C	NKX2-5	ENSTGUP00000036775	ENSTGUP00000030328	Myocyte enhancer factor 2C.	Homeobox domain-containing protein.	0.848
MYOCD	NKX2-5	ENSTGUP00000005984	ENSTGUP00000030328	Myocardin.	Homeobox domain-containing protein.	0.596
NKX2-5	MEF2A	ENSTGUP00000030328	ENSTGUP00000019739	Homeobox domain-containing protein.	Myocyte enhancer factor 2A.	0.780
NKX2-5	MEF2C	ENSTGUP00000030328	ENSTGUP00000036775	Homeobox domain-containing protein.	Myocyte enhancer factor 2C.	0.848
NKX2-5	MYOCD	ENSTGUP00000030328	ENSTGUP00000005984	Homeobox domain-containing protein.	Myocardin.	0.596