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ADGRF5 ADGRF5 TMEM175 TMEM175 NXNL2 NXNL2 BSG BSG TPP1 TPP1 SHH SHH MFSD2A MFSD2A DRAM2 DRAM2 MTF1 MTF1 SMO SMO BBS12 BBS12 VPS54 VPS54 NPHP4 NPHP4 ENSTGUP00000002856 ENSTGUP00000002856 SOX9 SOX9 WHRN WHRN HAAO HAAO PBLD PBLD MKS1 MKS1 LRRC45 LRRC45 VSIG1 VSIG1 TJP2 TJP2 CRB1 CRB1 ATP2B2 ATP2B2 IQCB1 IQCB1 IL20RB IL20RB SRF SRF CTNNB1 CTNNB1 SRC SRC SASH3 SASH3 TFF2 TFF2 ATP2A2 ATP2A2 HEXB HEXB H0Z6N8_TAEGU H0Z6N8_TAEGU MKKS MKKS BBS2 BBS2 CCDC66 CCDC66 BBS10 BBS10 HOMER2 HOMER2 ERCC6 ERCC6 FH FH LPCAT1 LPCAT1 RBP4 RBP4 SCGN SCGN LRRK1 LRRK1 FGGY FGGY CA7 CA7 CYTL1 CYTL1 CTSH CTSH CAV3 CAV3 MSTN MSTN BAG3 BAG3 CLRN1 CLRN1 WWTR1 WWTR1 PRDM14 PRDM14 IL7 IL7 CCN2 CCN2 RB1 RB1 USP45 USP45 STRAP STRAP LCA5 LCA5 NOX4 NOX4 IL17A IL17A ILDR2 ILDR2 CXADR CXADR KLHL10 KLHL10 BAX BAX H0ZZX0_TAEGU H0ZZX0_TAEGU CSRP3 CSRP3 PTH PTH NKIRAS2 NKIRAS2 ABCC8 ABCC8 ENSTGUP00000018771 ENSTGUP00000018771 CLN8 CLN8 FXN FXN NANOS1 NANOS1 FKBP14 FKBP14 LOC115491418 LOC115491418 CLDN5 CLDN5 SNX10 SNX10 SLC2A1 SLC2A1 ENSTGUP00000020975 ENSTGUP00000020975 USH1G USH1G NXNL1 NXNL1 INAVA INAVA DISC1 DISC1 CSF1 CSF1 ACP5 ACP5 CD34 CD34 TJP1 TJP1 TRAF6 TRAF6 FGF2 FGF2 TJP3 TJP3 ATP2B1 ATP2B1 GATA1 GATA1 ENSTGUP00000024967 ENSTGUP00000024967 TNFSF11 TNFSF11 PLN PLN ILDR1 ILDR1 SPATA7 SPATA7 PSEN1 PSEN1 ANKRD12 ANKRD12 CAV1 CAV1 CALB1 CALB1 MTM1 MTM1 ENSTGUP00000028186 ENSTGUP00000028186 RHO RHO EPAS1 EPAS1 ATP2A1 ATP2A1 NKIRAS1 NKIRAS1 KDR KDR CRB2 CRB2 ENSTGUP00000029281 ENSTGUP00000029281 APP APP LOX LOX CRACD CRACD TP53INP2 TP53INP2 H0ZSW1_TAEGU H0ZSW1_TAEGU USH1C USH1C ENSTGUP00000032701 ENSTGUP00000032701 PRKAA1 PRKAA1 ZNF830 ZNF830 USH2A USH2A CX3CL1 CX3CL1 ENSTGUP00000034860 ENSTGUP00000034860 IMMT IMMT GIGYF2 GIGYF2 ENSTGUP00000036004 ENSTGUP00000036004 ADGRV1 ADGRV1 P2RX1 P2RX1 MUC6 MUC6 CALB2 CALB2 BBS4 BBS4 ENSTGUP00000036780 ENSTGUP00000036780 PRLH PRLH TRIM32 TRIM32 VSTM4 VSTM4 IHH IHH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1348 aa)
TMEM175Uncharacterized protein. (496 aa)
NXNL2Nucleoredoxin like 2. (156 aa)
BSGBasigin (Ok blood group). (345 aa)
TPP1Tripeptidyl peptidase 1. (574 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (425 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (720 aa)
DRAM2DNA damage regulated autophagy modulator 2. (284 aa)
MTF1Metal regulatory transcription factor 1. (731 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (778 aa)
BBS12Bardet-Biedl syndrome 12. (703 aa)
VPS54VPS54 subunit of GARP complex. (969 aa)
NPHP4Nephrocystin 4. (1335 aa)
ENSTGUP00000002856annotation not available (519 aa)
SOX9SRY-box transcription factor 9. (474 aa)
WHRNWhirlin. (1025 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
PBLDPhenazine biosynthesis like protein domain containing. (286 aa)
MKS1Uncharacterized protein. (570 aa)
LRRC45Leucine rich repeat containing 45. (750 aa)
VSIG1V-set and immunoglobulin domain containing 1. (327 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1173 aa)
CRB1Uncharacterized protein. (1407 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1245 aa)
IQCB1IQ motif containing B1. (594 aa)
IL20RBInterleukin 20 receptor subunit beta. (307 aa)
SRFSerum response factor. (485 aa)
CTNNB1Catenin beta 1. (781 aa)
SRCTyrosine-protein kinase. (553 aa)
SASH3Uncharacterized protein. (568 aa)
TFF2Uncharacterized protein. (179 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1043 aa)
HEXBBeta-hexosaminidase. (560 aa)
H0Z6N8_TAEGURAMA domain-containing protein. (796 aa)
MKKSMcKusick-Kaufman syndrome. (583 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
CCDC66CCDC66 domain-containing protein. (963 aa)
BBS10Uncharacterized protein. (652 aa)
HOMER2Homer scaffold protein 2. (393 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1614 aa)
FHFumarate hydratase. (509 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (527 aa)
RBP4Retinol binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (226 aa)
SCGNSecretagogin, EF-hand calcium binding protein. (337 aa)
LRRK1Leucine rich repeat kinase 1. (1998 aa)
FGGYFGGY carbohydrate kinase domain containing. (550 aa)
CA7Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (264 aa)
CYTL1Cytokine like 1. (133 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (367 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
MSTNMyostatin. (375 aa)
BAG3BCL2 associated athanogene 3. (551 aa)
CLRN1Clarin 1. (232 aa)
WWTR1WW domain containing transcription regulator 1. (382 aa)
PRDM14PR/SET domain 14. (516 aa)
IL7Uncharacterized protein. (179 aa)
CCN2Cellular communication network factor 2. (347 aa)
RB1RB transcriptional corepressor 1. (931 aa)
USP45Ubiquitin carboxyl-terminal hydrolase. (817 aa)
STRAPSerine/threonine kinase receptor associated protein. (352 aa)
LCA5Lebercilin LCA5. (686 aa)
NOX4NADPH oxidase 4. (582 aa)
IL17AUncharacterized protein. (150 aa)
ILDR2IG domain-containing protein. (627 aa)
CXADRUncharacterized protein. (448 aa)
KLHL10Kelch like family member 10. (590 aa)
BAXBCL2 associated X, apoptosis regulator. (225 aa)
H0ZZX0_TAEGUIg-like domain-containing protein. (178 aa)
CSRP3Cysteine and glycine rich protein 3. (196 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
ABCC8ATP binding cassette subfamily C member 8. (1620 aa)
ENSTGUP00000018771annotation not available (490 aa)
CLN8TLC domain-containing protein. (300 aa)
FXNFrataxin. (235 aa)
NANOS1Nanos homolog 1. (258 aa)
FKBP14Peptidylprolyl isomerase. (215 aa)
LOC115491418Growth differentiation factor 11. (377 aa)
CLDN5Claudin-5. (216 aa)
SNX10Sorting nexin 10. (201 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (544 aa)
ENSTGUP00000020975LOW QUALITY PROTEIN: plasma membrane calcium-transporting ATPase 3-like. (1251 aa)
USH1GUSH1 protein network component sans. (469 aa)
NXNL1Nucleoredoxin-like protein 1. (218 aa)
INAVAInnate immunity activator protein. (520 aa)
DISC1DISC1 scaffold protein. (852 aa)
CSF1Macrophage colony-stimulating factor 1 precursor. (498 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (573 aa)
CD34Uncharacterized protein. (372 aa)
TJP1Uncharacterized protein; Belongs to the MAGUK family. (1859 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (1173 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
GATA1Erythroid transcription factor. (386 aa)
ENSTGUP00000024967annotation not available (473 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (317 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (540 aa)
SPATA7Uncharacterized protein. (578 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ANKRD12ANK_REP_REGION domain-containing protein. (2191 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CALB1Calbindin 1. (350 aa)
MTM1Myotubularin 1. (603 aa)
ENSTGUP00000028186annotation not available (368 aa)
RHORhodopsin. (351 aa)
EPAS1Endothelial PAS domain protein 1. (866 aa)
ATP2A1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1. (1187 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (162 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
CRB2Uncharacterized protein. (1464 aa)
ENSTGUP00000029281annotation not available (729 aa)
APPAmyloid beta precursor protein. (797 aa)
LOXLysyl oxidase. (453 aa)
CRACDKIAA1211. (1541 aa)
TP53INP2Uncharacterized protein. (234 aa)
H0ZSW1_TAEGUUncharacterized protein. (2025 aa)
USH1CHarmonin isoform X1. (556 aa)
ENSTGUP00000032701annotation not available (476 aa)
PRKAA1Non-specific serine/threonine protein kinase. (561 aa)
ZNF830Zinc finger protein 830. (431 aa)
USH2AUsherin. (5197 aa)
CX3CL1Uncharacterized protein. (429 aa)
ENSTGUP00000034860annotation not available (1271 aa)
IMMTMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (780 aa)
GIGYF2GYF domain-containing protein. (1277 aa)
ENSTGUP00000036004annotation not available (242 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6252 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
MUC6Mucin 6, oligomeric mucus/gel-forming. (1753 aa)
CALB2Taeniopygia guttata calbindin 2 (CALB2), mRNA. (349 aa)
BBS4Bardet-Biedl syndrome 4. (565 aa)
ENSTGUP00000036780annotation not available (1050 aa)
PRLHProlactin releasing hormone. (79 aa)
TRIM32Tripartite motif containing 32. (647 aa)
VSTM4V-set and transmembrane domain containing 4. (323 aa)
IHHIndian hedgehog signaling molecule. (408 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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