STRINGSTRING
ZBTB16 ZBTB16 SHH SHH ANXA6 ANXA6 CITED4 CITED4 WASF2 WASF2 DLX5 DLX5 H0YUE5_TAEGU H0YUE5_TAEGU RANBP3L RANBP3L SLC10A7 SLC10A7 LOC100222691 LOC100222691 SMAD1 SMAD1 LOC100231082 LOC100231082 SOX9 SOX9 HOXA11 HOXA11 SLC38A10 SLC38A10 TGFBR2 TGFBR2 NOTUM NOTUM BGLAP BGLAP SPNS2 SPNS2 GP9 GP9 MAPK11 MAPK11 PITX2 PITX2 ATP6AP1 ATP6AP1 MIGA2 MIGA2 BNC2 BNC2 FREM1 FREM1 CER1 CER1 SRF SRF SRC SRC ANXA2 ANXA2 ATG9A ATG9A TGM2 TGM2 GLG1 GLG1 SH2B3 SH2B3 IFITM5 IFITM5 TMEM119 TMEM119 SMPD3 SMPD3 MBTPS2 MBTPS2 KIT KIT RPL13 RPL13 EPYC EPYC FAM20C FAM20C SP5 SP5 PAFAH1B1 PAFAH1B1 LRRK1 LRRK1 ADAMTS7 ADAMTS7 MSX1 MSX1 FGF8 FGF8 EVC EVC EP300 EP300 LEPR LEPR BMPR2 BMPR2 IFT80 IFT80 SULF1 SULF1 RIPPLY2 RIPPLY2 GPR68 GPR68 MCPH1 MCPH1 TRIM45 TRIM45 THBS3 THBS3 IFT172 IFT172 FGF18 FGF18 LOC101234126 LOC101234126 OSTN OSTN P3H1 P3H1 ADAMTS7-2 ADAMTS7-2 LOC115490537 LOC115490537 BMP6 BMP6 OGN OGN PHOSPHO2 PHOSPHO2 INPPL1 INPPL1 FOXN3 FOXN3 GP1BB GP1BB SNX10 SNX10 CTC1 CTC1 TMEM38B TMEM38B NAB2 NAB2 ENSTGUP00000021519 ENSTGUP00000021519 ATG9B ATG9B ZFPM1 ZFPM1 SDC3 SDC3 CHAD CHAD PHOSPHO1 PHOSPHO1 ENSTGUP00000023326 ENSTGUP00000023326 AMER1 AMER1 NPPC NPPC PHEX PHEX TTC9 TTC9 ADAMTS12 ADAMTS12 SEMA4D SEMA4D MEF2D MEF2D TNFSF11 TNFSF11 LRP5 LRP5 ENSTGUP00000026806 ENSTGUP00000026806 ENSTGUP00000026997 ENSTGUP00000026997 LOC100231082-2 LOC100231082-2 PTPRC PTPRC DHRS3 DHRS3 MED1 MED1 LEP LEP SULF2 SULF2 PEX7 PEX7 NSD2 NSD2 LOC100229115 LOC100229115 ENSTGUP00000028636 ENSTGUP00000028636 FGF4 FGF4 ENSTGUP00000029384 ENSTGUP00000029384 LOC100222319 LOC100222319 AKAP13 AKAP13 PTPN6 PTPN6 DDR2 DDR2 ENSTGUP00000032218 ENSTGUP00000032218 ENSTGUP00000032655 ENSTGUP00000032655 ALPL ALPL SH3PXD2B SH3PXD2B MMP13 MMP13 TRIP11 TRIP11 RAB23 RAB23 ENSTGUP00000033975 ENSTGUP00000033975 TSKU TSKU LRRC17 LRRC17 BMPR1B BMPR1B EXT2 EXT2 IMPAD1 IMPAD1 FLI1 FLI1 ZNF385A ZNF385A CYP26B1 CYP26B1 MAPK14 MAPK14 MYOC MYOC ENSTGUP00000036454 ENSTGUP00000036454 ECM1 ECM1 ABI1 ABI1 IHH IHH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZBTB16Zinc finger and BTB domain containing 16. (644 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (425 aa)
ANXA6Annexin. (665 aa)
CITED4Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (204 aa)
WASF2WASP family member 2. (500 aa)
DLX5Distal-less homeobox 5. (290 aa)
H0YUE5_TAEGUMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (590 aa)
RANBP3LRAN binding protein 3 like. (544 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (345 aa)
LOC100222691SH2 domain-containing protein. (1057 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
LOC100231082Uncharacterized protein. (873 aa)
SOX9SRY-box transcription factor 9. (474 aa)
HOXA11Homeobox A11. (298 aa)
SLC38A10Solute carrier family 38 member 10. (1342 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (562 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (91 aa)
SPNS2Sphingolipid transporter 2. (524 aa)
GP9Glycoprotein IX platelet. (245 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
PITX2Homeobox protein. (360 aa)
ATP6AP1Uncharacterized protein. (458 aa)
MIGA2Mitoguardin 2. (589 aa)
BNC2Basonuclin 2. (1020 aa)
FREM1FRAS1 related extracellular matrix 1. (2193 aa)
CER1Cerberus 1, DAN family BMP antagonist. (273 aa)
SRFSerum response factor. (485 aa)
SRCTyrosine-protein kinase. (553 aa)
ANXA2Annexin. (345 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (869 aa)
TGM2Transglutaminase 2. (802 aa)
GLG1Golgi glycoprotein 1. (1139 aa)
SH2B3SH2B adaptor protein 3. (579 aa)
IFITM5Interferon induced transmembrane protein 5. (145 aa)
TMEM119Transmembrane protein 119. (354 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (660 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (503 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
RPL1360S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (302 aa)
EPYCEpiphycan. (316 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (560 aa)
SP5Sp5 transcription factor. (367 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (407 aa)
LRRK1Leucine rich repeat kinase 1. (1998 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1808 aa)
MSX1Msh homeobox 1. (291 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
EVCEvC ciliary complex subunit 1. (906 aa)
EP300E1A binding protein p300. (2445 aa)
LEPRUncharacterized protein. (1135 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
IFT80Intraflagellar transport 80. (267 aa)
SULF1Extracellular sulfatase. (1120 aa)
RIPPLY2Ripply transcriptional repressor 2. (175 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (358 aa)
MCPH1Microcephalin isoform X1. (868 aa)
TRIM45Tripartite motif containing 45. (527 aa)
THBS3Thrombospondin 3. (956 aa)
IFT172Uncharacterized protein. (1748 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC101234126Uncharacterized protein. (140 aa)
OSTNUncharacterized protein. (144 aa)
P3H1Prolyl 3-hydroxylase 1. (715 aa)
ADAMTS7-2A disintegrin and metalloproteinase with thrombospondin motifs 7. (998 aa)
LOC115490537Leptin receptor-like. (1122 aa)
BMP6Bone morphogenetic protein 6. (414 aa)
OGNOsteoglycin. (293 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
INPPL1Uncharacterized protein. (1323 aa)
FOXN3Forkhead box N3. (497 aa)
GP1BBPlatelet glycoprotein Ib beta chain. (186 aa)
SNX10Sorting nexin 10. (201 aa)
CTC1Uncharacterized protein. (1000 aa)
TMEM38BTransmembrane protein 38B. (343 aa)
NAB2NGFI-A-binding protein 2 isoform X1. (488 aa)
ENSTGUP00000021519annotation not available (333 aa)
ATG9BAutophagy related 9B. (991 aa)
ZFPM1Uncharacterized protein. (1560 aa)
SDC3Syndecan 3. (428 aa)
CHADUncharacterized protein. (392 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (265 aa)
ENSTGUP00000023326annotation not available (340 aa)
AMER1Uncharacterized protein. (1144 aa)
NPPCC-type natriuretic peptide. (120 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (751 aa)
TTC9Tetratricopeptide repeat domain 9. (209 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1626 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (1032 aa)
MEF2DMyocyte enhancer factor 2D. (594 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (317 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1595 aa)
ENSTGUP00000026806annotation not available (421 aa)
ENSTGUP00000026997annotation not available (687 aa)
LOC100231082-2Discoidin domain-containing receptor 2-like. (873 aa)
PTPRCUncharacterized protein. (1194 aa)
DHRS3Dehydrogenase/reductase 3. (324 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
LEPTaeniopygia guttata leptin (LEP), mRNA. (168 aa)
SULF2Extracellular sulfatase. (916 aa)
PEX7Peroxisomal biogenesis factor 7. (413 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1428 aa)
LOC100229115Fam20C domain-containing protein. (536 aa)
ENSTGUP00000028636annotation not available (121 aa)
FGF4Fibroblast growth factor 4. (194 aa)
ENSTGUP00000029384annotation not available (248 aa)
LOC100222319Uncharacterized protein. (710 aa)
AKAP13Uncharacterized protein. (2692 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (840 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (1179 aa)
ENSTGUP00000032218annotation not available (253 aa)
ENSTGUP00000032655annotation not available (422 aa)
ALPLAlkaline phosphatase, tissue-nonspecific isozyme. (518 aa)
SH3PXD2BUncharacterized protein. (881 aa)
MMP13Matrix metallopeptidase 13. (560 aa)
TRIP11Thyroid hormone receptor interactor 11. (1951 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
ENSTGUP00000033975annotation not available (497 aa)
TSKUTsukushi, small leucine rich proteoglycan. (383 aa)
LRRC17Uncharacterized protein. (438 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (756 aa)
IMPAD1Inositol monophosphatase domain containing 1. (358 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (459 aa)
ZNF385AZinc finger protein 385A. (327 aa)
CYP26B1Uncharacterized protein; Belongs to the cytochrome P450 family. (511 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MYOCMyocilin. (521 aa)
ENSTGUP00000036454annotation not available (693 aa)
ECM1Extracellular matrix protein 1. (419 aa)
ABI1Abl interactor 1. (586 aa)
IHHIndian hedgehog signaling molecule. (408 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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