STRINGSTRING
SMAD7 SMAD7 WNT11 WNT11 ENSTGUP00000020434 ENSTGUP00000020434 ZFPM1 ZFPM1 ACVR1 ACVR1 NSD2 NSD2 NKX2-5 NKX2-5 TBX3 TBX3 SMAD4 SMAD4 SLIT3 SLIT3 SAV1 SAV1 ZFPM2 ZFPM2 BMPR2 BMPR2 SLIT2 SLIT2 TBX2 TBX2 TGFBR1 TGFBR1 PITX2 PITX2 TGFBR2 TGFBR2 CITED4 CITED4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD7MH1 domain-containing protein. (392 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
ENSTGUP00000020434annotation not available (505 aa)
ZFPM1Uncharacterized protein. (1560 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1428 aa)
NKX2-5Homeobox domain-containing protein. (329 aa)
TBX3T-box transcription factor TBX3. (731 aa)
SMAD4SMAD family member 4. (514 aa)
SLIT3Slit guidance ligand 3. (1516 aa)
SAV1Salvador family WW domain containing protein 1. (379 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1179 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
SLIT2Slit guidance ligand 2. (1541 aa)
TBX2TBX domain-containing protein. (653 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (501 aa)
PITX2Homeobox protein. (360 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
CITED4Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (204 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.