(8 nodes) Atrial septum morphogenesis network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NSD2	Nuclear receptor binding SET domain protein 2. (1428 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (778 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
	ZFPM1	Uncharacterized protein. (1560 aa)
	ACVR1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
	NKX2-5	Homeobox domain-containing protein. (329 aa)
	TBX20	T-box transcription factor 20. (440 aa)
	CCN1	Cellular communication network factor 1. (412 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVR1	BMPR2	ENSTGUP00000027075	ENSTGUP00000010438	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.893
BMPR2	ACVR1	ENSTGUP00000010438	ENSTGUP00000027075	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.893
NKX2-5	NSD2	ENSTGUP00000030328	ENSTGUP00000028539	Homeobox domain-containing protein.	Nuclear receptor binding SET domain protein 2.	0.596
NKX2-5	TBX20	ENSTGUP00000030328	ENSTGUP00000036173	Homeobox domain-containing protein.	T-box transcription factor 20.	0.720
NSD2	NKX2-5	ENSTGUP00000028539	ENSTGUP00000030328	Nuclear receptor binding SET domain protein 2.	Homeobox domain-containing protein.	0.596
TBX20	NKX2-5	ENSTGUP00000036173	ENSTGUP00000030328	T-box transcription factor 20.	Homeobox domain-containing protein.	0.720