(13 nodes) R-SMAD binding network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSTGUP00000020434	annotation not available (505 aa)
	SMAD6	SMAD family member 6. (477 aa)
	SMURF1	E3 ubiquitin-protein ligase. (737 aa)
	MYOCD	Myocardin. (875 aa)
	DDX5	DEAD-box helicase 5; Belongs to the DEAD box helicase family. (781 aa)
	DROSHA	Drosha ribonuclease III. (1336 aa)
	AXIN1	Axin 1. (841 aa)
	SMAD4	SMAD family member 4. (514 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (370 aa)
	PMEPA1	Prostate transmembrane protein, androgen induced 1. (292 aa)
	RANBP3	RAN binding protein 3. (588 aa)
	ZC3H3	Uncharacterized protein. (943 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN1	SMURF1	ENSTGUP00000004469	ENSTGUP00000007875	Axin 1.	E3 ubiquitin-protein ligase.	0.644
DDX5	DROSHA	ENSTGUP00000004810	ENSTGUP00000002025	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Drosha ribonuclease III.	0.838
DDX5	FOS	ENSTGUP00000004810	ENSTGUP00000029395	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.410
DDX5	PMEPA1	ENSTGUP00000004810	ENSTGUP00000027930	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	Prostate transmembrane protein, androgen induced 1.	0.534
DROSHA	DDX5	ENSTGUP00000002025	ENSTGUP00000004810	Drosha ribonuclease III.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.838
ENSTGUP00000020434	PPM1A	ENSTGUP00000020434	ENSTGUP00000024539	annotation not available	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.658
ENSTGUP00000020434	SMAD6	ENSTGUP00000020434	ENSTGUP00000009751	annotation not available	SMAD family member 6.	0.643
ENSTGUP00000020434	SMURF1	ENSTGUP00000020434	ENSTGUP00000007875	annotation not available	E3 ubiquitin-protein ligase.	0.751
FOS	DDX5	ENSTGUP00000029395	ENSTGUP00000004810	Fos proto-oncogene, AP-1 transcription factor subunit.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.410
PMEPA1	DDX5	ENSTGUP00000027930	ENSTGUP00000004810	Prostate transmembrane protein, androgen induced 1.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.534
PPM1A	ENSTGUP00000020434	ENSTGUP00000024539	ENSTGUP00000020434	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	annotation not available	0.658
PPM1A	SMAD4	ENSTGUP00000024539	ENSTGUP00000032640	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	SMAD family member 4.	0.658
PPM1A	SMAD6	ENSTGUP00000024539	ENSTGUP00000009751	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	SMAD family member 6.	0.449
SMAD4	PPM1A	ENSTGUP00000032640	ENSTGUP00000024539	SMAD family member 4.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.658
SMAD4	SMAD6	ENSTGUP00000032640	ENSTGUP00000009751	SMAD family member 4.	SMAD family member 6.	0.643
SMAD4	SMURF1	ENSTGUP00000032640	ENSTGUP00000007875	SMAD family member 4.	E3 ubiquitin-protein ligase.	0.751
SMAD6	ENSTGUP00000020434	ENSTGUP00000009751	ENSTGUP00000020434	SMAD family member 6.	annotation not available	0.643
SMAD6	PPM1A	ENSTGUP00000009751	ENSTGUP00000024539	SMAD family member 6.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.449
SMAD6	SMAD4	ENSTGUP00000009751	ENSTGUP00000032640	SMAD family member 6.	SMAD family member 4.	0.643
SMAD6	SMURF1	ENSTGUP00000009751	ENSTGUP00000007875	SMAD family member 6.	E3 ubiquitin-protein ligase.	0.994