STRINGSTRING
CDC23 CDC23 KLHL18 KLHL18 GIPC3 GIPC3 DRD2 DRD2 LOC115497664 LOC115497664 NCAPG2 NCAPG2 DBF4 DBF4 ANKRD17 ANKRD17 BTC BTC H0YUE5_TAEGU H0YUE5_TAEGU MAD2L1 MAD2L1 CDC27 CDC27 FBXO42 FBXO42 DBF4B DBF4B PLK4 PLK4 CDC6 CDC6 LOC100231082 LOC100231082 KMT2E KMT2E RPTOR RPTOR DAZL DAZL IL1B IL1B CUL4B CUL4B TPR TPR RACGAP1 RACGAP1 KIF14 KIF14 GPSM2 GPSM2 LOC115497915 LOC115497915 ATAD5 ATAD5 CDC14A CDC14A CCND1 CCND1 ANAPC7 ANAPC7 EDN1 EDN1 POLDIP2 POLDIP2 ATRX ATRX ANAPC5 ANAPC5 CDC7 CDC7 CDC25B CDC25B HSF4 HSF4 H0Z8V6_TAEGU H0Z8V6_TAEGU SMPD3 SMPD3 RAD51C RAD51C E2F7 E2F7 CDT1 CDT1 CHEK2 CHEK2 CUL3 CUL3 MAD1L1 MAD1L1 RANBP1 RANBP1 SPAST SPAST PCID2 PCID2 CUL4A CUL4A STRA8 STRA8 TFDP1 TFDP1 CIT CIT LOC100222140 LOC100222140 MSX1 MSX1 FGF8 FGF8 SLF2 SLF2 MAP10 MAP10 THOC1 THOC1 ECT2 ECT2 UBXN2B UBXN2B SMC4 SMC4 MTRF1L MTRF1L RRM2B RRM2B RB1 RB1 RAD51AP1 RAD51AP1 MTBP MTBP NSMCE2 NSMCE2 DDX11 DDX11 DYNC1H1 DYNC1H1 XRCC3 XRCC3 CPSF3 CPSF3 ADAM17 ADAM17 RRM2 RRM2 ROCK2 ROCK2 GEN1 GEN1 RHNO1 RHNO1 DRD3 DRD3 LOC100222335 LOC100222335 LOC115498134 LOC115498134 E2F8 E2F8 ENSTGUP00000018634 ENSTGUP00000018634 ENSTGUP00000019468 ENSTGUP00000019468 PDGFB PDGFB H0Z6K5_TAEGU H0Z6K5_TAEGU LOC101234177 LOC101234177 ENSTGUP00000020898 ENSTGUP00000020898 LOC100217955 LOC100217955 WIZ WIZ LOC100217839 LOC100217839 ENSTGUP00000021498 ENSTGUP00000021498 FEN1 FEN1 PPP1R10 PPP1R10 LOC105759042 LOC105759042 CDC73 CDC73 MEPCE MEPCE CDC14B CDC14B CDC25A CDC25A LSM10 LSM10 H1A1Z5_TAEGU H1A1Z5_TAEGU PBK PBK LOC100222140-2 LOC100222140-2 CDC16 CDC16 LOC115493186 LOC115493186 STIL STIL UBE2C UBE2C LRP5 LRP5 STXBP4 STXBP4 RAD51B RAD51B INO80 INO80 ENSTGUP00000026720 ENSTGUP00000026720 ENSTGUP00000026997 ENSTGUP00000026997 NUMA1 NUMA1 LOC100231082-2 LOC100231082-2 RCC2 RCC2 CSPP1 CSPP1 NDC80 NDC80 GIPC2 GIPC2 LOC100219522 LOC100219522 H0YTV7_TAEGU H0YTV7_TAEGU ENSTGUP00000027764 ENSTGUP00000027764 SMC5 SMC5 CCND2 CCND2 MED1 MED1 LSM11 LSM11 ENSTGUP00000028596 ENSTGUP00000028596 LOC100231198 LOC100231198 THOC5 THOC5 APP APP EREG EREG RRM1 RRM1 SLF1 SLF1 PPP1R10-2 PPP1R10-2 NCAPG NCAPG ENSTGUP00000031243 ENSTGUP00000031243 MAD2L1BP MAD2L1BP DDR2 DDR2 USP19 USP19 SVIL SVIL HSF1 HSF1 CCND3 CCND3 MAP3K20 MAP3K20 ENSTGUP00000033975 ENSTGUP00000033975 CEP295 CEP295 LOC115498196 LOC115498196 CEP120 CEP120 CDC42 CDC42 ENSTGUP00000036315 ENSTGUP00000036315 STOX1 STOX1 PLRG1 PLRG1 ENSTGUP00000037171 ENSTGUP00000037171 NSFL1C NSFL1C ANXA1 ANXA1 LOC100226756 LOC100226756
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC23Cell division cycle 23. (585 aa)
KLHL18Kelch like family member 18. (651 aa)
GIPC3GIPC PDZ domain containing family member 3. (70 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (473 aa)
LOC115497664Ribonucleoside-diphosphate reductase large subunit. (801 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1150 aa)
DBF4DBF4 zinc finger. (708 aa)
ANKRD17Ankyrin repeat domain 17. (2488 aa)
BTCBetacellulin. (163 aa)
H0YUE5_TAEGUMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (590 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (208 aa)
CDC27Cell division cycle 27. (839 aa)
FBXO42F-box protein 42. (748 aa)
DBF4BUncharacterized protein. (749 aa)
PLK4Polo like kinase 4. (976 aa)
CDC6Cell division cycle 6. (558 aa)
LOC100231082Uncharacterized protein. (873 aa)
KMT2ELysine methyltransferase 2E. (1852 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1358 aa)
DAZLRRM domain-containing protein. (292 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (299 aa)
CUL4BCULLIN_2 domain-containing protein; Belongs to the cullin family. (888 aa)
TPRTPR_MLP1_2 domain-containing protein. (2313 aa)
RACGAP1Rac GTPase activating protein 1. (630 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1635 aa)
GPSM2G protein signaling modulator 2. (662 aa)
LOC115497915FAM83 domain-containing protein. (408 aa)
ATAD5ATPase family AAA domain containing 5. (1827 aa)
CDC14ACell division cycle 14A. (609 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
EDN1Endothelin 1. (202 aa)
POLDIP2ApaG domain-containing protein. (418 aa)
ATRXATRX chromatin remodeler. (2439 aa)
ANAPC5ANAPC5 domain-containing protein. (756 aa)
CDC7Cell division cycle 7. (584 aa)
CDC25BRhodanese domain-containing protein. (319 aa)
HSF4Heat shock transcription factor 4. (504 aa)
H0Z8V6_TAEGUGFA domain-containing protein. (376 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (660 aa)
RAD51CRECA_2 domain-containing protein. (367 aa)
E2F7E2F transcription factor 7. (900 aa)
CDT1Chromatin licensing and DNA replication factor 1. (597 aa)
CHEK2Checkpoint kinase 2. (532 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (723 aa)
RANBP1RAN binding protein 1. (226 aa)
SPASTSpastin; Belongs to the AAA ATPase family. (611 aa)
PCID2PCI domain containing 2. (400 aa)
CUL4ACullin 4A; Belongs to the cullin family. (936 aa)
STRA8Stimulated by retinoic acid 8. (310 aa)
TFDP1Transcription factor. (412 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2076 aa)
LOC100222140Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
MSX1Msh homeobox 1. (291 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
SLF2Uncharacterized protein. (1023 aa)
MAP10HPHLAWLY domain-containing protein. (575 aa)
THOC1THO complex 1. (740 aa)
ECT2Uncharacterized protein. (985 aa)
UBXN2BUncharacterized protein. (340 aa)
SMC4Structural maintenance of chromosomes protein. (1317 aa)
MTRF1LF-box protein 5. (592 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (347 aa)
RB1RB transcriptional corepressor 1. (931 aa)
RAD51AP1RAD51_interact domain-containing protein. (277 aa)
MTBPMDM2 binding protein. (1041 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (284 aa)
DDX11DEAD/H-box helicase 11. (894 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4309 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (347 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (1029 aa)
ADAM17ADAM metallopeptidase domain 17. (918 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (397 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1483 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (935 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (269 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (493 aa)
LOC100222335EGF-like domain-containing protein. (158 aa)
LOC115498134Uncharacterized protein. (690 aa)
E2F8E2F transcription factor 8. (896 aa)
ENSTGUP00000018634annotation not available (359 aa)
ENSTGUP00000019468annotation not available (572 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (278 aa)
H0Z6K5_TAEGUUncharacterized protein. (1418 aa)
LOC101234177Piwi-like protein 2. (908 aa)
ENSTGUP00000020898annotation not available (338 aa)
LOC100217955Condensin complex subunit 2. (716 aa)
WIZC2H2-type domain-containing protein. (1765 aa)
LOC100217839HSF_DOMAIN domain-containing protein. (624 aa)
ENSTGUP00000021498annotation not available (382 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (396 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (866 aa)
LOC105759042Protein kinase domain-containing protein. (559 aa)
CDC73Cell division cycle 73. (531 aa)
MEPCEMethylphosphate capping enzyme. (547 aa)
CDC14BUncharacterized protein. (568 aa)
CDC25ACell division cycle 25A. (532 aa)
LSM10Sm domain-containing protein. (123 aa)
H1A1Z5_TAEGUUncharacterized protein. (761 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase. (687 aa)
LOC100222140-2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1077 aa)
CDC16Cell division cycle 16. (589 aa)
LOC115493186RNA polymerase II-associated factor 1 homolog. (521 aa)
STILUncharacterized protein. (1346 aa)
UBE2CUbiquitin-conjugating enzyme E2 C. (179 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1595 aa)
STXBP4Syntaxin binding protein 4. (723 aa)
RAD51BRAD51 paralog B. (400 aa)
INO80INO80 complex ATPase subunit. (1558 aa)
ENSTGUP00000026720annotation not available (295 aa)
ENSTGUP00000026997annotation not available (687 aa)
NUMA1Uncharacterized protein. (1667 aa)
LOC100231082-2Discoidin domain-containing receptor 2-like. (873 aa)
RCC2Protein RCC2. (1203 aa)
CSPP1Uncharacterized protein. (1139 aa)
NDC80NDC80 kinetochore complex component. (640 aa)
GIPC2GIPC PDZ domain containing family member 2. (290 aa)
LOC100219522NAD-dependent protein deacetylase sirtuin-2-like. (455 aa)
H0YTV7_TAEGUANK_REP_REGION domain-containing protein. (2496 aa)
ENSTGUP00000027764annotation not available (358 aa)
SMC5AAA_15 domain-containing protein. (1094 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (309 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
LSM11LSM11, U7 small nuclear RNA associated. (366 aa)
ENSTGUP00000028596annotation not available (620 aa)
LOC100231198F-box only protein 42. (634 aa)
THOC5Uncharacterized protein. (710 aa)
APPAmyloid beta precursor protein. (797 aa)
EREGEpiregulin. (167 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
SLF1BRCT domain-containing protein. (932 aa)
PPP1R10-2Serine/threonine-protein phosphatase 1 regulatory subunit 10. (898 aa)
NCAPGNon-SMC condensin I complex subunit G. (1006 aa)
ENSTGUP00000031243annotation not available (686 aa)
MAD2L1BPMAD2L1 binding protein. (381 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (1179 aa)
USP19Ubiquitin specific peptidase 19; Belongs to the peptidase C19 family. (1423 aa)
SVILSupervillin. (2128 aa)
HSF1Heat shock factor protein 1 isoform X1. (689 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (333 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (476 aa)
ENSTGUP00000033975annotation not available (497 aa)
CEP295ALMS_motif domain-containing protein. (1854 aa)
LOC115498196Protransforming growth factor alpha-like. (316 aa)
CEP120Centrosomal protein 120. (1009 aa)
CDC42Cell division cycle 42. (302 aa)
ENSTGUP00000036315annotation not available (861 aa)
STOX1Stork_head domain-containing protein. (850 aa)
PLRG1WD_REPEATS_REGION domain-containing protein. (669 aa)
ENSTGUP00000037171annotation not available (491 aa)
NSFL1CUncharacterized protein. (440 aa)
ANXA1Annexin. (364 aa)
LOC100226756FAM83 domain-containing protein. (565 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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