node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAM22 | CACNG2 | ENSTGUP00000025851 | ENSTGUP00000011052 | ADAM metallopeptidase domain 22. | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.706 |
CACNG2 | ADAM22 | ENSTGUP00000011052 | ENSTGUP00000025851 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | ADAM metallopeptidase domain 22. | 0.706 |
CACNG2 | CACNG4 | ENSTGUP00000011052 | ENSTGUP00000004516 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.431 |
CACNG2 | GRIA1 | ENSTGUP00000011052 | ENSTGUP00000034140 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor AMPA type subunit 1. | 0.954 |
CACNG2 | GRIA2 | ENSTGUP00000011052 | ENSTGUP00000005705 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor AMPA type subunit 2. | 0.934 |
CACNG2 | GRIN2A | ENSTGUP00000011052 | ENSTGUP00000004929 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor NMDA type subunit 2A. | 0.454 |
CACNG2 | GRIN2B | ENSTGUP00000011052 | ENSTGUP00000009760 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor NMDA type subunit 2B. | 0.477 |
CACNG2 | GRIN2C | ENSTGUP00000011052 | ENSTGUP00000009145 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor NMDA type subunit 2C. | 0.427 |
CACNG2 | GRIN3A | ENSTGUP00000011052 | ENSTGUP00000000673 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | 0.589 |
CACNG3 | GRIA1 | ENSTGUP00000021994 | ENSTGUP00000034140 | Calcium voltage-gated channel auxiliary subunit gamma 3. | Glutamate ionotropic receptor AMPA type subunit 1. | 0.422 |
CACNG3 | GRIA2 | ENSTGUP00000021994 | ENSTGUP00000005705 | Calcium voltage-gated channel auxiliary subunit gamma 3. | Glutamate ionotropic receptor AMPA type subunit 2. | 0.735 |
CACNG4 | CACNG2 | ENSTGUP00000004516 | ENSTGUP00000011052 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | 0.431 |
CACNG4 | GRIA1 | ENSTGUP00000004516 | ENSTGUP00000034140 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor AMPA type subunit 1. | 0.576 |
CACNG4 | GRIA2 | ENSTGUP00000004516 | ENSTGUP00000005705 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor AMPA type subunit 2. | 0.772 |
CACNG4 | GRIN2A | ENSTGUP00000004516 | ENSTGUP00000004929 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor NMDA type subunit 2A. | 0.414 |
CACNG4 | GRIN2B | ENSTGUP00000004516 | ENSTGUP00000009760 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Glutamate ionotropic receptor NMDA type subunit 2B. | 0.405 |
CACNG5 | GRIA1 | ENSTGUP00000025000 | ENSTGUP00000034140 | Calcium voltage-gated channel auxiliary subunit gamma 5. | Glutamate ionotropic receptor AMPA type subunit 1. | 0.452 |
CACNG5 | GRIA2 | ENSTGUP00000025000 | ENSTGUP00000005705 | Calcium voltage-gated channel auxiliary subunit gamma 5. | Glutamate ionotropic receptor AMPA type subunit 2. | 0.411 |
ENSTGUP00000004504 | GRIA2 | ENSTGUP00000004504 | ENSTGUP00000005705 | annotation not available | Glutamate ionotropic receptor AMPA type subunit 2. | 0.417 |
ENSTGUP00000021114 | GRIA2 | ENSTGUP00000021114 | ENSTGUP00000005705 | annotation not available | Glutamate ionotropic receptor AMPA type subunit 2. | 0.417 |