(43 nodes) GABA-ergic synapse network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NRXN1	Neurexin 1. (1499 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (473 aa)
	GABRG2	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
	GABRD	Gamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
	SLC6A1	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (598 aa)
	ATP2B2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1245 aa)
	BSN	Uncharacterized protein. (3784 aa)
	DAG1	Dystroglycan 1. (896 aa)
	NLGN3	Neuroligin 3. (813 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (959 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (478 aa)
	LRRTM1	Leucine rich repeat transmembrane neuronal 1. (485 aa)
	CTBP2	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (420 aa)
	LOC115493455	a_DG1_N2 domain-containing protein. (579 aa)
	GABRR2	Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (545 aa)
	GABRR1	Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (478 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (233 aa)
	CLSTN3	Calsyntenin 3. (1017 aa)
	ERC2	ELKS/RAB6-interacting/CAST family member 2. (956 aa)
	LRRTM2	Leucine rich repeat transmembrane neuronal 2. (517 aa)
	CSPG5	Chondroitin sulfate proteoglycan 5 isoform X1. (528 aa)
	ABHD6	Abhydrolase domain containing 6. (336 aa)
	C1QBP	Complement C1q binding protein. (287 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (5193 aa)
	ENSTGUP00000020975	LOW QUALITY PROTEIN: plasma membrane calcium-transporting ATPase 3-like. (1251 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (1006 aa)
	NLGN4X	COesterase domain-containing protein. (836 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (494 aa)
	GABRA3	Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (580 aa)
	ATP2B1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
	SLC6A6	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (687 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
	IQSEC3	IQ motif and Sec7 domain 3. (1167 aa)
	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9. (1537 aa)
	NRXN2	Neurexin 2. (1546 aa)
	NLGN2	Neuroligin 2. (1086 aa)
	ENSTGUP00000032412	annotation not available (208 aa)
	GABRA2	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
	ENSTGUP00000034860	annotation not available (1271 aa)
	NPTN	Neuroplastin. (396 aa)
	LRFN5	Leucine rich repeat and fibronectin type III domain containing 5. (772 aa)
	NLGN1	COesterase domain-containing protein. (854 aa)
	ENSTGUP00000036627	annotation not available (283 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF9	GABRA2	ENSTGUP00000026764	ENSTGUP00000032631	Cdc42 guanine nucleotide exchange factor 9.	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.758
ARHGEF9	GABRA3	ENSTGUP00000026764	ENSTGUP00000024273	Cdc42 guanine nucleotide exchange factor 9.	Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.407
ARHGEF9	GABRA5	ENSTGUP00000026764	ENSTGUP00000025754	Cdc42 guanine nucleotide exchange factor 9.	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.471
ARHGEF9	GABRG2	ENSTGUP00000026764	ENSTGUP00000001513	Cdc42 guanine nucleotide exchange factor 9.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.412
ARHGEF9	GLRB	ENSTGUP00000026764	ENSTGUP00000022944	Cdc42 guanine nucleotide exchange factor 9.	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.546
BSN	CTBP1	ENSTGUP00000005239	ENSTGUP00000010999	Uncharacterized protein.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.623
BSN	CTBP2	ENSTGUP00000005239	ENSTGUP00000011819	Uncharacterized protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.623
BSN	ERC2	ENSTGUP00000005239	ENSTGUP00000038634	Uncharacterized protein.	ELKS/RAB6-interacting/CAST family member 2.	0.474
BSN	PCLO	ENSTGUP00000005239	ENSTGUP00000020806	Uncharacterized protein.	Piccolo presynaptic cytomatrix protein.	0.602
CLSTN3	LRRTM1	ENSTGUP00000013650	ENSTGUP00000011265	Calsyntenin 3.	Leucine rich repeat transmembrane neuronal 1.	0.675
CTBP1	BSN	ENSTGUP00000010999	ENSTGUP00000005239	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.623
CTBP1	CTBP2	ENSTGUP00000010999	ENSTGUP00000011819	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.900
CTBP2	BSN	ENSTGUP00000011819	ENSTGUP00000005239	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.623
CTBP2	CTBP1	ENSTGUP00000011819	ENSTGUP00000010999	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.900
ENSTGUP00000032412	ENSTGUP00000036627	ENSTGUP00000032412	ENSTGUP00000036627	annotation not available	annotation not available	0.899
ENSTGUP00000036627	ENSTGUP00000032412	ENSTGUP00000036627	ENSTGUP00000032412	annotation not available	annotation not available	0.899
ERC2	BSN	ENSTGUP00000038634	ENSTGUP00000005239	ELKS/RAB6-interacting/CAST family member 2.	Uncharacterized protein.	0.474
GABBR2	GABRG2	ENSTGUP00000008802	ENSTGUP00000001513	Gamma-aminobutyric acid type B receptor subunit 2.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.455
GABRA2	ARHGEF9	ENSTGUP00000032631	ENSTGUP00000026764	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Cdc42 guanine nucleotide exchange factor 9.	0.758
GABRA2	GABRA3	ENSTGUP00000032631	ENSTGUP00000024273	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.487