65 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (473 aa)
	CBARP	LOW QUALITY PROTEIN: voltage-dependent calcium channel beta subunit-associated regulatory protein. (772 aa)
	CNR2	Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	RAP1A	Uncharacterized protein. (184 aa)
	SYTL4	Synaptotagmin like 4. (717 aa)
	TNFRSF1B	Uncharacterized protein. (457 aa)
	VAMP3	V-SNARE coiled-coil homology domain-containing protein. (393 aa)
	NDUFAF2	NADH:ubiquinone oxidoreductase complex assembly factor 2. (171 aa)
	NPVF	Uncharacterized protein. (193 aa)
	RAB11FIP3	RAB11 family interacting protein 3. (755 aa)
	PIM3	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (322 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (330 aa)
	PNKD	Uncharacterized protein. (376 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1030 aa)
	PSMD9	Uncharacterized protein. (209 aa)
	PRL	Prolactin. (209 aa)
	CYP19A1	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (509 aa)
	IL1RAPL1	Interleukin 1 receptor accessory protein like 1. (622 aa)
	RHBDF2	Rhomboid 5 homolog 2. (823 aa)
	KCNJ11	Potassium voltage-gated channel subfamily J member 11. (401 aa)
	SIRT4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (315 aa)
	KLF7	Kruppel like factor 7. (330 aa)
	LIF	LIF interleukin 6 family cytokine. (211 aa)
	TRH	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (300 aa)
	OPRM1	Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (410 aa)
	FGF23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (253 aa)
	CCN3	Cellular communication network factor 3. (377 aa)
	RSAD2	Radical S-adenosyl methionine domain containing 2. (352 aa)
	TNFRSF1A	Uncharacterized protein. (429 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (493 aa)
	SYT11	Synaptotagmin 11. (484 aa)
	H0ZYT8_TAEGU	Uncharacterized protein. (1509 aa)
	ABCC8	ATP binding cassette subfamily C member 8. (1620 aa)
	MIDN	Midnolin. (743 aa)
	STXBP3	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
	RAP1A-2	Ras-related protein Rap-1A. (184 aa)
	FRMD4A	FERM domain containing 4A. (1067 aa)
	ENSTGUP00000022252	annotation not available (149 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	SRCIN1	SRC kinase signaling inhibitor 1 isoform X8. (1230 aa)
	REST	RE1 silencing transcription factor. (893 aa)
	RAB11FIP1	FIP-RBD domain-containing protein. (1362 aa)
	RABGEF1	Uncharacterized protein. (538 aa)
	ADTRP	Androgen dependent TFPI regulating protein. (267 aa)
	FFAR4	Free fatty acid receptor 4. (354 aa)
	SERGEF	Secretion regulating guanine nucleotide exchange factor. (409 aa)
	LOC115497877	OX-2 membrane glycoprotein-like. (407 aa)
	IGF1	Insulin like growth factor 1. (153 aa)
	LEP	Taeniopygia guttata leptin (LEP), mRNA. (168 aa)
	CNR1	Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP (By similarity). In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. In [...] (499 aa)
	RHBDF1	Rhomboid 5 homolog 1. (892 aa)
	FAM3D	Uncharacterized protein. (289 aa)
	LOC115494778	Treacle protein-like. (779 aa)
	TNFRSF8	Uncharacterized protein. (480 aa)
	KCNB1	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (862 aa)
	VAMP8	Vesicle-associated membrane protein 8. (75 aa)
	RAB33B	RAB33B, member RAS oncogene family. (228 aa)
	RAP1B	RAP1B, member of RAS oncogene family. (184 aa)
	SYT4	Uncharacterized protein. (571 aa)
	GJA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
	INHBB	Inhibin beta B chain. (392 aa)
	FMR1	Fragile X mental retardation 1. (548 aa)
	UCN	Urocortin. (99 aa)
	ACVR1C	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (363 aa)
	ANXA1	Annexin. (364 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC8	KCNJ11	ENSTGUP00000018402	ENSTGUP00000008936	ATP binding cassette subfamily C member 8.	Potassium voltage-gated channel subfamily J member 11.	0.997
ACVR1C	INHBB	ENSTGUP00000038228	ENSTGUP00000037093	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Inhibin beta B chain.	0.813
CRHBP	UCN	ENSTGUP00000004187	ENSTGUP00000037922	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urocortin.	0.862
DRD2	DRD4	ENSTGUP00000000268	ENSTGUP00000022980	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.772
DRD3	DRD4	ENSTGUP00000013801	ENSTGUP00000022980	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.718
DRD4	DRD2	ENSTGUP00000022980	ENSTGUP00000000268	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.772
DRD4	DRD3	ENSTGUP00000022980	ENSTGUP00000013801	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.718
ENSTGUP00000022252	STXBP3	ENSTGUP00000022252	ENSTGUP00000020433	annotation not available	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.608
FGF23	INHBB	ENSTGUP00000012632	ENSTGUP00000037093	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Inhibin beta B chain.	0.414
FGF23	LEP	ENSTGUP00000012632	ENSTGUP00000028222	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Taeniopygia guttata leptin (LEP), mRNA.	0.472
H0ZYT8_TAEGU	RAB11FIP3	ENSTGUP00000018343	ENSTGUP00000003875	Uncharacterized protein.	RAB11 family interacting protein 3.	0.580
HMGCR	NPVF	ENSTGUP00000006291	ENSTGUP00000002951	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Uncharacterized protein.	0.571
INHBB	ACVR1C	ENSTGUP00000037093	ENSTGUP00000038228	Inhibin beta B chain.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.813
INHBB	FGF23	ENSTGUP00000037093	ENSTGUP00000012632	Inhibin beta B chain.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.414
INHBB	LEP	ENSTGUP00000037093	ENSTGUP00000028222	Inhibin beta B chain.	Taeniopygia guttata leptin (LEP), mRNA.	0.408
KCNJ11	ABCC8	ENSTGUP00000008936	ENSTGUP00000018402	Potassium voltage-gated channel subfamily J member 11.	ATP binding cassette subfamily C member 8.	0.997
KCNJ11	SERGEF	ENSTGUP00000008936	ENSTGUP00000026327	Potassium voltage-gated channel subfamily J member 11.	Secretion regulating guanine nucleotide exchange factor.	0.511
LEP	FGF23	ENSTGUP00000028222	ENSTGUP00000012632	Taeniopygia guttata leptin (LEP), mRNA.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.472
LEP	INHBB	ENSTGUP00000028222	ENSTGUP00000037093	Taeniopygia guttata leptin (LEP), mRNA.	Inhibin beta B chain.	0.408
LEP	NPVF	ENSTGUP00000028222	ENSTGUP00000002951	Taeniopygia guttata leptin (LEP), mRNA.	Uncharacterized protein.	0.536