STRINGSTRING
LOC100225657-2 LOC100225657-2 CFTR CFTR CAPN10 CAPN10 BMP4 BMP4 ENSTGUP00000024522 ENSTGUP00000024522 CADPS2 CADPS2 RAB27A RAB27A ADCYAP1 ADCYAP1 ENSTGUP00000022493 ENSTGUP00000022493 SEC11A SEC11A SDC1 SDC1 FRMD4A FRMD4A CREB1 CREB1 ENSTGUP00000021421 ENSTGUP00000021421 RAB3GAP1 RAB3GAP1 HYAL3 HYAL3 ACSL4 ACSL4 ENSTGUP00000020434 ENSTGUP00000020434 RPH3AL RPH3AL LOC105758760 LOC105758760 GALR1 GALR1 MYOM2 MYOM2 ENSTGUP00000019696 ENSTGUP00000019696 C1QTNF6 C1QTNF6 BMP6 BMP6 EXOC1 EXOC1 ADORA2B ADORA2B SEC11C SEC11C GOLPH3L GOLPH3L PINK1 PINK1 VPS4A VPS4A H0ZT62_TAEGU H0ZT62_TAEGU BLK BLK ARF6 ARF6 GAB2 GAB2 GPR68 GPR68 CPB2 CPB2 TM7SF3 TM7SF3 RFX6 RFX6 PDX1 PDX1 SELENOT SELENOT CRH CRH VIP VIP EZR EZR LOC100220528 LOC100220528 TRH TRH PLA2G6 PLA2G6 LOC100225657 LOC100225657 MYOM1 MYOM1 TMF1 TMF1 LAMP1 LAMP1 NR1H4 NR1H4 TSG101 TSG101 RBP4 RBP4 UNC13D UNC13D SPHK1 SPHK1 H0Z9J4_TAEGU H0Z9J4_TAEGU CYP19A1 CYP19A1 CACNA1H CACNA1H SYT7 SYT7 GPLD1 GPLD1 VEGFC VEGFC LOC100219822 LOC100219822 PCSK1 PCSK1 PSMD9 PSMD9 KIAA0100 KIAA0100 TRPM2 TRPM2 EDN1 EDN1 FSHR FSHR PPID PPID LOC100220779 LOC100220779 FGG FGG SYT9 SYT9 PARD6A PARD6A PLA2G10 PLA2G10 AACS AACS GHRH GHRH SLC4A8 SLC4A8 SNX4 SNX4 AIMP1 AIMP1 TGFBR2 TGFBR2 C1QTNF1 C1QTNF1 SYTL4 SYTL4 DAB2 DAB2 VPS4B VPS4B GOLPH3 GOLPH3 CLASP2 CLASP2 PDCD6IP PDCD6IP APBB3 APBB3 HMMR HMMR STAM STAM SIRT6 SIRT6 NR0B2 NR0B2 SYK SYK GHRHR GHRHR DRD2 DRD2 C2CD2L C2CD2L GATA1 GATA1 HGS HGS PTGES PTGES GLUD1 GLUD1 CLASP1 CLASP1 TNFSF11 TNFSF11 FFAR4 FFAR4 ADCY8 ADCY8 TUNAR TUNAR ILDR1 ILDR1 CACNA1I CACNA1I PTPN23 PTPN23 IGF1 IGF1 LRRC8A LRRC8A TNFRSF11A TNFRSF11A TMED10 TMED10 ENSTGUP00000028843 ENSTGUP00000028843 CADPS CADPS DTNBP1 DTNBP1 KCNB1 KCNB1 VAMP8 VAMP8 MPC2 MPC2 TGFB2 TGFB2 GNRH1 GNRH1 CDK5 CDK5 CACNA1G CACNA1G ENSTGUP00000031778 ENSTGUP00000031778 CARTPT CARTPT SMAD4 SMAD4 IER3IP1 IER3IP1 EXPH5 EXPH5 SRI SRI NMB NMB SYT4 SYT4 MYRIP MYRIP CACNB4 CACNB4 INHBB INHBB PLA2G4A PLA2G4A LOC115496603 LOC115496603 ENSTGUP00000037897 ENSTGUP00000037897 UCN UCN ENSTGUP00000037956 ENSTGUP00000037956 GRP GRP DNM1L DNM1L
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC100225657-2Protein wntless homolog. (541 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (672 aa)
BMP4Bone morphogenetic protein 4. (420 aa)
ENSTGUP00000024522annotation not available (197 aa)
CADPS2Uncharacterized protein. (1301 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (172 aa)
ENSTGUP00000022493annotation not available (159 aa)
SEC11ASignal peptidase complex catalytic subunit SEC11. (405 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (315 aa)
FRMD4AFERM domain containing 4A. (1067 aa)
CREB1cAMP responsive element binding protein 1. (324 aa)
ENSTGUP00000021421annotation not available (1349 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (987 aa)
HYAL3Hyaluronidase. (446 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
ENSTGUP00000020434annotation not available (505 aa)
RPH3ALDouble C2 domain beta. (310 aa)
LOC105758760Uncharacterized protein. (1184 aa)
GALR1Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (361 aa)
MYOM2Myomesin 2. (1456 aa)
ENSTGUP00000019696annotation not available (133 aa)
C1QTNF6C1q and TNF related 6. (319 aa)
BMP6Bone morphogenetic protein 6. (414 aa)
EXOC1Sec3-PIP2_bind domain-containing protein. (905 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (348 aa)
SEC11CSignal peptidase complex catalytic subunit SEC11. (173 aa)
GOLPH3LUncharacterized protein. (284 aa)
PINK1PTEN induced kinase 1. (515 aa)
VPS4AAAA domain-containing protein. (446 aa)
H0ZT62_TAEGUPhospholipase A(2). (255 aa)
BLKTyrosine-protein kinase. (499 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (142 aa)
GAB2GRB2 associated binding protein 2. (680 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (358 aa)
CPB2Carboxypeptidase B2. (424 aa)
TM7SF3Transmembrane 7 superfamily member 3. (563 aa)
RFX6Regulatory factor X6. (884 aa)
PDX1Homeobox domain-containing protein. (260 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (137 aa)
CRHCorticotropin releasing hormone. (178 aa)
VIPVasoactive intestinal peptide. (215 aa)
EZREzrin. (586 aa)
LOC100220528Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (171 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (300 aa)
PLA2G6Phospholipase A2 group VI. (805 aa)
LOC100225657Wnt ligand secretion mediator. (541 aa)
MYOM1Myomesin 1. (1687 aa)
TMF1TATA element modulatory factor 1. (1103 aa)
LAMP1Lysosomal associated membrane protein 1. (415 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (473 aa)
TSG101Tumor susceptibility 101. (377 aa)
RBP4Retinol binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (226 aa)
UNC13DUnc-13 homolog D. (1057 aa)
SPHK1DAGKc domain-containing protein. (629 aa)
H0Z9J4_TAEGUG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
CYP19A1Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (509 aa)
CACNA1HVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2284 aa)
SYT7Synaptotagmin 7. (684 aa)
GPLD1Zn_dep_PLPC domain-containing protein. (834 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (468 aa)
LOC100219822ZP domain-containing protein. (459 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
PSMD9Uncharacterized protein. (209 aa)
KIAA0100KIAA0100. (2103 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1541 aa)
EDN1Endothelin 1. (202 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (693 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
LOC100220779Sec3_C domain-containing protein. (718 aa)
FGGFibrinogen gamma chain. (433 aa)
SYT9Uncharacterized protein. (519 aa)
PARD6APar-6 family cell polarity regulator alpha. (357 aa)
PLA2G10Phospholipase A(2). (158 aa)
AACSAcetoacetyl-CoA synthetase. (667 aa)
GHRHGrowth hormone releasing hormone. (154 aa)
SLC4A8Anion exchange protein. (1078 aa)
SNX4Sorting nexin 4. (441 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (318 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
C1QTNF1Uncharacterized protein. (276 aa)
SYTL4Synaptotagmin like 4. (717 aa)
DAB2DAB adaptor protein 2. (716 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (441 aa)
GOLPH3Golgi phosphoprotein 3. (313 aa)
CLASP2Cytoplasmic linker associated protein 2. (1408 aa)
PDCD6IPBRO1 domain-containing protein. (878 aa)
APBB3Amyloid beta precursor protein binding family B member 3. (475 aa)
HMMRHyaluronan mediated motility receptor. (731 aa)
STAMSignal transducing adaptor molecule. (532 aa)
SIRT6Sirtuin 6. (348 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (265 aa)
SYKTyrosine-protein kinase. (668 aa)
GHRHRUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (425 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (473 aa)
C2CD2LC2CD2 like. (601 aa)
GATA1Erythroid transcription factor. (386 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (897 aa)
PTGESProstaglandin E synthase. (220 aa)
GLUD1Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (555 aa)
CLASP1Uncharacterized protein. (1555 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (317 aa)
FFAR4Free fatty acid receptor 4. (354 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1319 aa)
TUNARTCL1 upstream neural differentiation-associated RNA. (48 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (540 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2090 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1595 aa)
IGF1Insulin like growth factor 1. (153 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
TNFRSF11ATNFR-Cys domain-containing protein. (663 aa)
TMED10Transmembrane p24 trafficking protein 10. (223 aa)
ENSTGUP00000028843annotation not available (398 aa)
CADPSUncharacterized protein. (1355 aa)
DTNBP1Dystrobrevin binding protein 1. (351 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (862 aa)
VAMP8Vesicle-associated membrane protein 8. (75 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (156 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (433 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (357 aa)
CDK5Cyclin-dependent-like kinase 5. (808 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2305 aa)
ENSTGUP00000031778annotation not available (337 aa)
CARTPTCART prepropeptide. (137 aa)
SMAD4SMAD family member 4. (514 aa)
IER3IP1Immediate early response 3-interacting protein 1 precursor. (91 aa)
EXPH5Exophilin-5 isoform X1. (1839 aa)
SRIPutative sorcin transcript variant 1. (323 aa)
NMBUncharacterized protein. (154 aa)
SYT4Uncharacterized protein. (571 aa)
MYRIPRab_eff_C domain-containing protein. (895 aa)
CACNB4SH3 domain-containing protein. (478 aa)
INHBBInhibin beta B chain. (392 aa)
PLA2G4APhospholipase A2. (748 aa)
LOC115496603Zona pellucida sperm-binding protein 3-like. (426 aa)
ENSTGUP00000037897annotation not available (399 aa)
UCNUrocortin. (99 aa)
ENSTGUP00000037956annotation not available (102 aa)
GRPUncharacterized protein. (147 aa)
DNM1LUncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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