(31 nodes) Regulation of leukocyte apoptotic process network (Taeniopygia guttata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRELID1	PRELI domain containing 1. (215 aa)
	ANXA1	Annexin. (364 aa)
	PTCRA	Pre T-cell antigen receptor alpha. (286 aa)
	GAS6	Growth arrest specific 6. (704 aa)
	FADD	Fas associated via death domain. (221 aa)
	ENSTGUP00000032655	annotation not available (422 aa)
	CCL19	C-C motif chemokine ligand 19. (152 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1804 aa)
	KIFAP3	Kinesin associated protein 3. (798 aa)
	LYN	Tyrosine-protein kinase. (605 aa)
	EFNA1	Ephrin A1; Belongs to the ephrin family. (210 aa)
	PDCD1	Programmed cell death protein 1 isoform X1. (282 aa)
	PIK3CB	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	ENSTGUP00000021519	annotation not available (333 aa)
	CD74	Uncharacterized protein. (289 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
	BAX	BCL2 associated X, apoptosis regulator. (225 aa)
	BLK	Tyrosine-protein kinase. (499 aa)
	LGALS3	Galectin. (303 aa)
	BCL11B	BAF chromatin remodeling complex subunit BCL11B. (883 aa)
	H0ZQ02_TAEGU	Uncharacterized protein. (480 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (847 aa)
	SELENOS	Selenoprotein S. (188 aa)
	BCL2L1	BCL2 like 1. (230 aa)
	DOCK8	Dedicator of cytokinesis 8; Belongs to the DOCK family. (2099 aa)
	NOC2L	Uncharacterized protein. (777 aa)
	SIRT1	Sirtuin 1. (750 aa)
	IL7R	Interleukin 7 receptor. (460 aa)
	SLC7A11	Solute carrier family 7 member 11. (503 aa)
	SLC46A2	Solute carrier family 46 member 2. (452 aa)
	IL10	Interleukin 10. (165 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	ENSTGUP00000021519	ENSTGUP00000038342	ENSTGUP00000021519	Annexin.	annotation not available	0.601
ANXA1	ENSTGUP00000032655	ENSTGUP00000038342	ENSTGUP00000032655	Annexin.	annotation not available	0.601
ANXA1	LGALS3	ENSTGUP00000038342	ENSTGUP00000013465	Annexin.	Galectin.	0.432
BAX	BCL2L1	ENSTGUP00000015983	ENSTGUP00000006866	BCL2 associated X, apoptosis regulator.	BCL2 like 1.	0.993
BAX	ENSTGUP00000021519	ENSTGUP00000015983	ENSTGUP00000021519	BCL2 associated X, apoptosis regulator.	annotation not available	0.612
BAX	ENSTGUP00000032655	ENSTGUP00000015983	ENSTGUP00000032655	BCL2 associated X, apoptosis regulator.	annotation not available	0.612
BCL2L1	BAX	ENSTGUP00000006866	ENSTGUP00000015983	BCL2 like 1.	BCL2 associated X, apoptosis regulator.	0.993
BCL2L1	ENSTGUP00000021519	ENSTGUP00000006866	ENSTGUP00000021519	BCL2 like 1.	annotation not available	0.908
BCL2L1	ENSTGUP00000032655	ENSTGUP00000006866	ENSTGUP00000032655	BCL2 like 1.	annotation not available	0.908
BCL2L1	FADD	ENSTGUP00000006866	ENSTGUP00000034889	BCL2 like 1.	Fas associated via death domain.	0.438
BCL2L1	PIK3CB	ENSTGUP00000006866	ENSTGUP00000021600	BCL2 like 1.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.407
CCL19	IL10	ENSTGUP00000030305	ENSTGUP00000001118	C-C motif chemokine ligand 19.	Interleukin 10.	0.410
ENSTGUP00000021519	ANXA1	ENSTGUP00000021519	ENSTGUP00000038342	annotation not available	Annexin.	0.601
ENSTGUP00000021519	BAX	ENSTGUP00000021519	ENSTGUP00000015983	annotation not available	BCL2 associated X, apoptosis regulator.	0.612
ENSTGUP00000021519	BCL2L1	ENSTGUP00000021519	ENSTGUP00000006866	annotation not available	BCL2 like 1.	0.908
ENSTGUP00000021519	NOC2L	ENSTGUP00000021519	ENSTGUP00000004101	annotation not available	Uncharacterized protein.	0.672
ENSTGUP00000021519	SIRT1	ENSTGUP00000021519	ENSTGUP00000003586	annotation not available	Sirtuin 1.	0.806
ENSTGUP00000032655	ANXA1	ENSTGUP00000032655	ENSTGUP00000038342	annotation not available	Annexin.	0.601
ENSTGUP00000032655	BAX	ENSTGUP00000032655	ENSTGUP00000015983	annotation not available	BCL2 associated X, apoptosis regulator.	0.612
ENSTGUP00000032655	BCL2L1	ENSTGUP00000032655	ENSTGUP00000006866	annotation not available	BCL2 like 1.	0.908