(92 nodes) Sarcomere network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IGDCC3	Immunoglobulin superfamily DCC subclass member 3. (776 aa)
	MYL3	Myosin light chain 3. (193 aa)
	KLHL40	Kelch like family member 40. (619 aa)
	TTC12	TPR_REGION domain-containing protein. (704 aa)
	LRRC2	Leucine rich repeat containing 2. (372 aa)
	MYOZ3	Myozenin 3. (274 aa)
	MYOM3	Myomesin 3. (821 aa)
	MYOT	Myotilin. (639 aa)
	TNNT2	Troponin T2, cardiac type. (188 aa)
	H0YSX2_TAEGU	Uncharacterized protein. (1220 aa)
	TMOD1	Tropomodulin 1. (391 aa)
	MYOZ2	Myozenin 2. (263 aa)
	MYPN	Uncharacterized protein. (1329 aa)
	LMOD2	Leiomodin 2. (541 aa)
	UNC45B	Unc-45 myosin chaperone B. (929 aa)
	PRRC2B	Protein PRRC2B isoform X5. (2229 aa)
	LRRC39	Leucine rich repeat containing 39. (339 aa)
	LDB3	PDZ domain-containing protein. (283 aa)
	PALLD	Palladin, cytoskeletal associated protein. (1445 aa)
	TNNC2	Troponin C2, fast skeletal type. (436 aa)
	LOC100219752	Uncharacterized protein. (588 aa)
	LRRC10B	Leucine rich repeat containing 10B. (266 aa)
	TMOD3	Uncharacterized protein. (351 aa)
	KY	Kyphoscoliosis peptidase. (672 aa)
	TMOD2	Tropomodulin 2. (351 aa)
	ITGB1BP2	Integrin subunit beta 1 binding protein 2. (354 aa)
	PDLIM1	PDZ and LIM domain 1. (383 aa)
	ANKRD1	Ankyrin repeat domain 1. (359 aa)
	SMTNL2	Smoothelin like 2. (292 aa)
	EVA1A	Uncharacterized protein. (486 aa)
	KCTD6	Potassium channel tetramerization domain containing 6. (237 aa)
	LMOD3	Uncharacterized protein. (569 aa)
	CAPN9	Calpain 9; Belongs to the peptidase C2 family. (690 aa)
	MYOM1	Myomesin 1. (1687 aa)
	UNC45A	Unc-45 myosin chaperone A. (734 aa)
	ACTN2	Actinin alpha 2. (897 aa)
	TXLNB	Taxilin beta. (684 aa)
	TRIM55	Tripartite motif containing 55. (537 aa)
	NEB	Nebulin. (5578 aa)
	FHL5	Four and a half LIM domains 5. (280 aa)
	SMPX	Small muscle protein X-linked. (89 aa)
	TNNI2	Troponin I2, fast skeletal type. (237 aa)
	MYL4	Uncharacterized protein. (203 aa)
	ENSTGUP00000037857	annotation not available (261 aa)
	TRIM32	Tripartite motif containing 32. (647 aa)
	VCL	Uncharacterized protein. (1068 aa)
	MYBPC1	Myosin binding protein C, slow type. (1199 aa)
	TNNI1	Troponin I1, slow skeletal type. (241 aa)
	ANKRD2	Ankyrin repeat domain 2. (291 aa)
	TNNC1	Troponin C1, slow skeletal and cardiac type. (176 aa)
	ROBO3	Roundabout, axon guidance receptor 3. (620 aa)
	SYNPO2L	Synaptopodin 2 like. (1084 aa)
	SRI	Putative sorcin transcript variant 1. (323 aa)
	ILK	Integrin linked kinase. (676 aa)
	TNNT3	Troponin T3, fast skeletal type. (387 aa)
	PPP1R12B-2	Protein phosphatase 1 regulatory subunit 12B. (187 aa)
	LRRC10	Uncharacterized protein. (251 aa)
	TMOD4	Tropomodulin 4. (178 aa)
	CAPN3	Calpain 3; Belongs to the peptidase C2 family. (809 aa)
	CAVIN4	Caveolae associated protein 4. (377 aa)
	LMOD1	Leiomodin 1. (664 aa)
	ASB2	Ankyrin repeat and SOCS box containing 2. (668 aa)
	MTM1	Myotubularin 1. (603 aa)
	PPP1R12A	Protein phosphatase 1 regulatory subunit. (1072 aa)
	FHL2	Uncharacterized protein. (280 aa)
	SPHKAP	SPHK1 interactor, AKAP domain containing. (1682 aa)
	TRIM54	Tripartite motif containing 54. (543 aa)
	SYNPO2	Synaptopodin 2. (1274 aa)
	GGPS1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (434 aa)
	MYBPC2	Myosin-binding protein C, fast-type. (1318 aa)
	PPP1R12B	Protein phosphatase 1 regulatory subunit. (910 aa)
	ENSTGUP00000024172	annotation not available (696 aa)
	TRIM63	Tripartite motif containing 63. (447 aa)
	TCAP	Telethonin. (118 aa)
	FBXL22	F-box and leucine rich repeat protein 22. (223 aa)
	PDLIM3	PDZ and LIM domain 3. (403 aa)
	H0Z5M1_TAEGU	Uncharacterized protein. (273 aa)
	CHORDC1	Cysteine and histidine rich domain containing 1. (331 aa)
	TMEFF1	Uncharacterized protein. (397 aa)
	MTMR12	Myotubularin related protein 12. (770 aa)
	FHL3	Four and a half LIM domains 3. (364 aa)
	ENSTGUP00000020888	annotation not available (1099 aa)
	PYROXD1	Pyridine nucleotide-disulphide oxidoreductase domain 1. (499 aa)
	SYNC	Syncoilin, intermediate filament protein. (549 aa)
	TNNI3	Troponin I3, cardiac type. (181 aa)
	MYOM2	Myomesin 2. (1456 aa)
	MYBPC3	Myosin binding protein C, cardiac. (1254 aa)
	CAPZA1	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (288 aa)
	TMOD4-2	Tropomodulin 4. (340 aa)
	CSRP3	Cysteine and glycine rich protein 3. (196 aa)
	ROBO2	Uncharacterized protein. (1467 aa)
	EVA1C	Uncharacterized protein. (436 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	CSRP3	ENSTGUP00000010782	ENSTGUP00000016201	Actinin alpha 2.	Cysteine and glycine rich protein 3.	0.598
ACTN2	ENSTGUP00000020888	ENSTGUP00000010782	ENSTGUP00000020888	Actinin alpha 2.	annotation not available	0.541
ACTN2	H0Z5M1_TAEGU	ENSTGUP00000010782	ENSTGUP00000022814	Actinin alpha 2.	Uncharacterized protein.	0.442
ACTN2	LOC100219752	ENSTGUP00000010782	ENSTGUP00000006401	Actinin alpha 2.	Uncharacterized protein.	0.457
ACTN2	MYBPC1	ENSTGUP00000010782	ENSTGUP00000035965	Actinin alpha 2.	Myosin binding protein C, slow type.	0.541
ACTN2	MYBPC2	ENSTGUP00000010782	ENSTGUP00000024745	Actinin alpha 2.	Myosin-binding protein C, fast-type.	0.541
ACTN2	MYBPC3	ENSTGUP00000010782	ENSTGUP00000018570	Actinin alpha 2.	Myosin binding protein C, cardiac.	0.541
ACTN2	MYL3	ENSTGUP00000010782	ENSTGUP00000000210	Actinin alpha 2.	Myosin light chain 3.	0.565
ACTN2	MYL4	ENSTGUP00000010782	ENSTGUP00000038051	Actinin alpha 2.	Uncharacterized protein.	0.546
ACTN2	MYOT	ENSTGUP00000010782	ENSTGUP00000001228	Actinin alpha 2.	Myotilin.	0.540
ACTN2	MYOZ2	ENSTGUP00000010782	ENSTGUP00000001945	Actinin alpha 2.	Myozenin 2.	0.701
ACTN2	MYPN	ENSTGUP00000010782	ENSTGUP00000003680	Actinin alpha 2.	Uncharacterized protein.	0.510
ACTN2	NEB	ENSTGUP00000010782	ENSTGUP00000012432	Actinin alpha 2.	Nebulin.	0.598
ACTN2	PALLD	ENSTGUP00000010782	ENSTGUP00000006244	Actinin alpha 2.	Palladin, cytoskeletal associated protein.	0.510
ACTN2	PDLIM1	ENSTGUP00000010782	ENSTGUP00000007359	Actinin alpha 2.	PDZ and LIM domain 1.	0.497
ACTN2	PDLIM3	ENSTGUP00000010782	ENSTGUP00000022967	Actinin alpha 2.	PDZ and LIM domain 3.	0.614
ACTN2	SMPX	ENSTGUP00000010782	ENSTGUP00000038533	Actinin alpha 2.	Small muscle protein X-linked.	0.404
ACTN2	TCAP	ENSTGUP00000010782	ENSTGUP00000023683	Actinin alpha 2.	Telethonin.	0.667
ACTN2	TMOD1	ENSTGUP00000010782	ENSTGUP00000001536	Actinin alpha 2.	Tropomodulin 1.	0.472
ACTN2	TMOD2	ENSTGUP00000010782	ENSTGUP00000007111	Actinin alpha 2.	Tropomodulin 2.	0.420