(65 nodes) Small GTPase network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB17	RAB17, member RAS oncogene family. (213 aa)
	RAB11B	Uncharacterized protein. (267 aa)
	RHEB	Uncharacterized protein. (254 aa)
	NRAS	NRAS proto-oncogene, GTPase. (280 aa)
	RAP1A	Uncharacterized protein. (184 aa)
	RAB5C	Putative RAB5C member RAS oncogene family variant 3. (216 aa)
	RASEF	RAS and EF-hand domain containing. (721 aa)
	LOC100231666	Uncharacterized protein. (216 aa)
	RAN	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (394 aa)
	MRAS	Muscle RAS oncogene homolog. (347 aa)
	RAB33A	RAB33A, member RAS oncogene family. (228 aa)
	RHOBTB1	Rho related BTB domain containing 1. (694 aa)
	RHOD	Ras homolog family member D. (198 aa)
	RHOF	Ras homolog family member F, filopodia associated. (268 aa)
	RAB34	RAB34, member RAS oncogene family. (303 aa)
	RAB26	RAB26, member RAS oncogene family. (263 aa)
	RHOA	Uncharacterized protein. (193 aa)
	LOC100226244	Uncharacterized protein. (191 aa)
	RAB21	RAB21, member RAS oncogene family. (220 aa)
	RASD1	Ras related dexamethasone induced 1. (278 aa)
	H0ZBL0_TAEGU	Uncharacterized protein. (208 aa)
	RAB7A	RAB7A, member RAS oncogene family. (209 aa)
	RRAS2	RAS related 2. (203 aa)
	RAB20	RAB20, member RAS oncogene family. (235 aa)
	RAB3B	RAB3B, member RAS oncogene family. (226 aa)
	RAB11A	RAB11A, member RAS oncogene family. (216 aa)
	RRAD	RRAD, Ras related glycolysis inhibitor and calcium channel regulator. (296 aa)
	HRAS	Putative v-Ha-ras Harvey sarcoma viral oncogene variant 2. (189 aa)
	RAB12	RAB12, member RAS oncogene family. (386 aa)
	RAB36	Uncharacterized protein. (290 aa)
	RAC2	Rac family small GTPase 2. (206 aa)
	RAB32	RAB32, member RAS oncogene family. (218 aa)
	LOC101234096	Uncharacterized protein. (210 aa)
	RHOV	Uncharacterized protein. (231 aa)
	RASD2	RASD family member 2. (266 aa)
	GEM	GTP binding protein overexpressed in skeletal muscle. (297 aa)
	RND3	Rho family GTPase 3. (244 aa)
	RAB38	RAB38, member RAS oncogene family. (294 aa)
	CRACR2A	Calcium release activated channel regulator 2A. (705 aa)
	RAB6A	Uncharacterized protein. (215 aa)
	NKIRAS2	NFKB inhibitor interacting Ras like 2. (191 aa)
	RAP2C	RAP2C, member of RAS oncogene family. (505 aa)
	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (1085 aa)
	ARHGAP5	Rho GTPase activating protein 5. (1505 aa)
	RAB4A	RAB4A, member RAS oncogene family. (248 aa)
	RAB25	RAB25, member RAS oncogene family. (291 aa)
	RAB28	RAB28, member RAS oncogene family. (222 aa)
	RAB8A	RAB8A, member RAS oncogene family. (263 aa)
	LOC100225382	Uncharacterized protein. (1621 aa)
	DIRAS3	Putative Di-Ras2 variant 1. (198 aa)
	RASL11A	RAS like family 11 member A. (286 aa)
	RALA	Putative Ras family small GTP binding protein RALA. (206 aa)
	RAC1	Rac family small GTPase 1. (255 aa)
	RASL12	RAS like family 12. (406 aa)
	RAB35	RAB35, member RAS oncogene family. (376 aa)
	RHOT1	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (707 aa)
	RHOBTB2	Rho related BTB domain containing 2. (821 aa)
	RAC3	Rac family small GTPase 3. (229 aa)
	RAB1A	RAB1A, member RAS oncogene family. (484 aa)
	RAB2A	RAB2A, member RAS oncogene family. (272 aa)
	RAB14	Uncharacterized protein. (268 aa)
	CDC42	Cell division cycle 42. (302 aa)
	MXD3	MAX dimerization protein 3. (293 aa)
	CPLANE2	Uncharacterized protein. (274 aa)
	AGAP1	Uncharacterized protein. (1172 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP5	CDC42	ENSTGUP00000020218	ENSTGUP00000036310	Rho GTPase activating protein 5.	Cell division cycle 42.	0.485
ARHGAP5	LOC100225382	ENSTGUP00000020218	ENSTGUP00000023753	Rho GTPase activating protein 5.	Uncharacterized protein.	0.902
ARHGAP5	LOC100226244	ENSTGUP00000020218	ENSTGUP00000007228	Rho GTPase activating protein 5.	Uncharacterized protein.	0.432
ARHGAP5	RHOA	ENSTGUP00000020218	ENSTGUP00000006808	Rho GTPase activating protein 5.	Uncharacterized protein.	0.961
ARHGAP5	RHOD	ENSTGUP00000020218	ENSTGUP00000006140	Rho GTPase activating protein 5.	Ras homolog family member D.	0.513
ARHGAP5	RHOF	ENSTGUP00000020218	ENSTGUP00000006251	Rho GTPase activating protein 5.	Ras homolog family member F, filopodia associated.	0.513
ARHGAP5	RND3	ENSTGUP00000020218	ENSTGUP00000012353	Rho GTPase activating protein 5.	Rho family GTPase 3.	0.680
CDC42	ARHGAP5	ENSTGUP00000036310	ENSTGUP00000020218	Cell division cycle 42.	Rho GTPase activating protein 5.	0.485
CDC42	LOC100225382	ENSTGUP00000036310	ENSTGUP00000023753	Cell division cycle 42.	Uncharacterized protein.	0.526
CDC42	LOC100226244	ENSTGUP00000036310	ENSTGUP00000007228	Cell division cycle 42.	Uncharacterized protein.	0.629
CDC42	RAB7A	ENSTGUP00000036310	ENSTGUP00000008087	Cell division cycle 42.	RAB7A, member RAS oncogene family.	0.575
CDC42	RAC1	ENSTGUP00000036310	ENSTGUP00000026723	Cell division cycle 42.	Rac family small GTPase 1.	0.966
CDC42	RAC2	ENSTGUP00000036310	ENSTGUP00000010983	Cell division cycle 42.	Rac family small GTPase 2.	0.966
CDC42	RAC3	ENSTGUP00000036310	ENSTGUP00000034636	Cell division cycle 42.	Rac family small GTPase 3.	0.679
CDC42	RHOA	ENSTGUP00000036310	ENSTGUP00000006808	Cell division cycle 42.	Uncharacterized protein.	0.512
CDC42	RHOD	ENSTGUP00000036310	ENSTGUP00000006140	Cell division cycle 42.	Ras homolog family member D.	0.415
CDC42	RHOF	ENSTGUP00000036310	ENSTGUP00000006251	Cell division cycle 42.	Ras homolog family member F, filopodia associated.	0.436
CDC42	RHOV	ENSTGUP00000036310	ENSTGUP00000011103	Cell division cycle 42.	Uncharacterized protein.	0.582
CDC42	RND3	ENSTGUP00000036310	ENSTGUP00000012353	Cell division cycle 42.	Rho family GTPase 3.	0.451
HRAS	NRAS	ENSTGUP00000010191	ENSTGUP00000001014	Putative v-Ha-ras Harvey sarcoma viral oncogene variant 2.	NRAS proto-oncogene, GTPase.	0.900