79 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MATK	Tyrosine-protein kinase. (443 aa)
	ZAP70	Tyrosine-protein kinase. (609 aa)
	SYK	Tyrosine-protein kinase. (668 aa)
	INSR	Insulin receptor. (1323 aa)
	H0YQF7_TAEGU	Protein kinase domain-containing protein. (245 aa)
	ITK	Tyrosine-protein kinase. (631 aa)
	PDGFRB	Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1092 aa)
	CSF1R	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	FLT4	Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1379 aa)
	MUSK	Muscle associated receptor tyrosine kinase. (938 aa)
	TEK	TEK receptor tyrosine kinase. (1117 aa)
	LCK	Protein kinase domain-containing protein. (513 aa)
	EGFR	Receptor protein-tyrosine kinase. (1222 aa)
	EPHA2	EPH receptor A2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1004 aa)
	PLK4	Polo like kinase 4. (976 aa)
	LOC100231082	Uncharacterized protein. (873 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
	PRAG1	PEAK1 related, kinase-activating pseudokinase 1. (1370 aa)
	SRC	Tyrosine-protein kinase. (553 aa)
	FGFR1	Fibroblast growth factor receptor. (820 aa)
	MST1R	Macrophage stimulating 1 receptor. (1419 aa)
	JAK2	Tyrosine-protein kinase. (1130 aa)
	MET	MET proto-oncogene, receptor tyrosine kinase. (1385 aa)
	TP53RK	TP53 regulating kinase. (293 aa)
	LOC100229347	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1311 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1104 aa)
	HCK	Tyrosine-protein kinase. (508 aa)
	EPHB1	EPH receptor B1. (1003 aa)
	TIE1	Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1124 aa)
	SRMS	Tyrosine-protein kinase. (491 aa)
	KIT	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	EPHA4	EPH receptor A4. (1011 aa)
	TEC	Tyrosine-protein kinase. (630 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1363 aa)
	LMTK2	Lemur tyrosine kinase 2. (1505 aa)
	ROR1-2	Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	EPHB3	Receptor protein-tyrosine kinase. (991 aa)
	FGFR3	Fibroblast growth factor receptor. (794 aa)
	TYRO3	TYRO3 protein tyrosine kinase. (872 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1244 aa)
	FLT1	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1325 aa)
	FRK	Tyrosine-protein kinase. (527 aa)
	STYK1	Serine/threonine/tyrosine kinase 1. (425 aa)
	EPHA7	EPH receptor A7. (1020 aa)
	EPHA1	EPH receptor A1. (962 aa)
	BLK	Tyrosine-protein kinase. (499 aa)
	EPHA3	EPH receptor A3. (937 aa)
	BTK	Tyrosine-protein kinase. (662 aa)
	JAK3	Janus kinase 3. (1113 aa)
	EPHA8	EPH receptor A8. (984 aa)
	INSRR	Uncharacterized protein. (1323 aa)
	FLT3	Protein kinase domain-containing protein. (1019 aa)
	ABL2	Tyrosine-protein kinase. (1160 aa)
	FGFR4	Fibroblast growth factor receptor. (865 aa)
	TNK2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1208 aa)
	NTRK2	Tyrosine-protein kinase receptor. (842 aa)
	MERTK	MER proto-oncogene, tyrosine kinase. (982 aa)
	TESK1	Testis associated actin remodelling kinase 1. (692 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	FGR	Tyrosine-protein kinase. (617 aa)
	NTRK3	Tyrosine-protein kinase receptor. (852 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
	LYN	Tyrosine-protein kinase. (605 aa)
	ABL1	Tyrosine-protein kinase. (1139 aa)
	FGFR2	Fibroblast growth factor receptor. (891 aa)
	TXK	TXK tyrosine kinase. (546 aa)
	LTK	Tyrosine-protein kinase receptor. (1505 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (831 aa)
	ROR2	Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (938 aa)
	EPHB6	EPH receptor B6. (1000 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1109 aa)
	DDR2	Discoidin domain receptor tyrosine kinase 2. (1179 aa)
	EPHA5	EPH receptor A5. (1020 aa)
	LOC115496244	Tyrosine-protein kinase. (1148 aa)
	ROS1	Tyrosine-protein kinase receptor. (2290 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	EPHB2	EPH receptor B2. (995 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSTGUP00000026063	ENSTGUP00000018887	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
ABL2	ABL1	ENSTGUP00000018887	ENSTGUP00000026063	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
BLK	EGFR	ENSTGUP00000013694	ENSTGUP00000001863	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.459
BLK	ERBB4	ENSTGUP00000013694	ENSTGUP00000011850	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.459
BLK	FER	ENSTGUP00000013694	ENSTGUP00000035485	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.418
BLK	FES	ENSTGUP00000013694	ENSTGUP00000029426	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.450
BLK	MATK	ENSTGUP00000013694	ENSTGUP00000000136	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.613
BLK	MET	ENSTGUP00000013694	ENSTGUP00000005389	Tyrosine-protein kinase.	MET proto-oncogene, receptor tyrosine kinase.	0.618
BLK	MST1R	ENSTGUP00000013694	ENSTGUP00000005191	Tyrosine-protein kinase.	Macrophage stimulating 1 receptor.	0.618
BLK	PDGFRB	ENSTGUP00000013694	ENSTGUP00000000985	Tyrosine-protein kinase.	Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.417
BLK	PTK2	ENSTGUP00000013694	ENSTGUP00000024177	Tyrosine-protein kinase.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.486
BLK	SYK	ENSTGUP00000013694	ENSTGUP00000000435	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.478
BLK	ZAP70	ENSTGUP00000013694	ENSTGUP00000000339	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.487
BTK	CSF1R	ENSTGUP00000015504	ENSTGUP00000000996	Tyrosine-protein kinase.	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.421
BTK	HCK	ENSTGUP00000015504	ENSTGUP00000006771	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.426
BTK	KIT	ENSTGUP00000015504	ENSTGUP00000007975	Tyrosine-protein kinase.	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.418
BTK	LCK	ENSTGUP00000015504	ENSTGUP00000001461	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.478
BTK	LYN	ENSTGUP00000015504	ENSTGUP00000024943	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.774
BTK	MET	ENSTGUP00000015504	ENSTGUP00000005389	Tyrosine-protein kinase.	MET proto-oncogene, receptor tyrosine kinase.	0.614
BTK	MST1R	ENSTGUP00000015504	ENSTGUP00000005191	Tyrosine-protein kinase.	Macrophage stimulating 1 receptor.	0.666