STRINGSTRING
HSF4 HSF4 RFX2 RFX2 LARP1 LARP1 RPA2 RPA2 E2F2 E2F2 CUL2 CUL2 ELF3 ELF3 RIOK2 RIOK2 IRF1 IRF1 IRF6-2 IRF6-2 FOXI1 FOXI1 WRN WRN SPDEF SPDEF CUL1 CUL1 FOXF2 FOXF2 PSMD11 PSMD11 PSMD3 PSMD3 CDC6 CDC6 PLEK PLEK ELF2 ELF2 DEPDC1B DEPDC1B COPS4 COPS4 ETV4 ETV4 DVL1 DVL1 UBR2 UBR2 CUL4B CUL4B ADAR ADAR FOXF1 FOXF1 FOXC2 FOXC2 FOXL1 FOXL1 PSMD12 PSMD12 EIF3M EIF3M DEPDC7 DEPDC7 ERG ERG ETS2 ETS2 MND1 MND1 FOXL2 FOXL2 RFX3 RFX3 FOXB1 FOXB1 E2F4 E2F4 KAT6A KAT6A POLR3F POLR3F FOXN1 FOXN1 ARID2 ARID2 ETV5 ETV5 HFM1 HFM1 DUSP15-2 DUSP15-2 PSMD13 PSMD13 FOXN4 FOXN4 COPS2 COPS2 COPS3 COPS3 E2F7 E2F7 FOXA2 FOXA2 CDT1 CDT1 FOXK1 FOXK1 CUL3 CUL3 METAP2 METAP2 ELK3 ELK3 GPR155 GPR155 DEPDC4 DEPDC4 PREX1 PREX1 CUL4A CUL4A LOC100227298 LOC100227298 TFDP1 TFDP1 LOC100221426 LOC100221426 DEPDC5 DEPDC5 BLM BLM EHF EHF DVL3 DVL3 STN1 STN1 H1-0 H1-0 ASMTL ASMTL SHPRH SHPRH FOXI2 FOXI2 RFX4 RFX4 UBR1 UBR1 SPIC SPIC PREX2 PREX2 PLEK2 PLEK2 E2F5 E2F5 RFX6 RFX6 FOXO1 FOXO1 FOXO3 FOXO3 ASCC3 ASCC3 RAD21 RAD21 GTF2F2 GTF2F2 CUL5 CUL5 E2F6 E2F6 FOXJ2 FOXJ2 FOXM1 FOXM1 GABPA GABPA E2F8 E2F8 SSB SSB EIF3E EIF3E ELF1 ELF1 VPS36 VPS36 LARP7 LARP7 IRF2 IRF2 FOXN3 FOXN3 PIKFYVE PIKFYVE LOC100217839 LOC100217839 GPS1 GPS1 HSF2 HSF2 RGS6 RGS6 GTF2E2 GTF2E2 LOC100221446 LOC100221446 RGS7 RGS7 H0ZAX6_TAEGU H0ZAX6_TAEGU RGS11 RGS11 IRF4 IRF4 FOXP1 FOXP1 RAPGEF4 RAPGEF4 CUL9 CUL9 FOXK2 FOXK2 ETV6 ETV6 FOXP4 FOXP4 DEPTOR DEPTOR IRF8 IRF8 LOC100224409 LOC100224409 LARP4B LARP4B RAPGEF5 RAPGEF5 FOXN2 FOXN2 LARP4 LARP4 ETV1 ETV1 ELL ELL RGS9 RGS9 E2F3 E2F3 FOXP2 FOXP2 ASMT ASMT RFX8 RFX8 ORC1 ORC1 HP1BP3 HP1BP3 DEPDC1 DEPDC1 LARP1B LARP1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HSF4Heat shock transcription factor 4. (504 aa)
RFX2Regulatory factor X2. (726 aa)
LARP1La ribonucleoprotein domain family member 1. (1002 aa)
RPA2Replication protein A2. (274 aa)
E2F2E2F transcription factor 2. (450 aa)
CUL2Cullin 2; Belongs to the cullin family. (742 aa)
ELF3E74 like ETS transcription factor 3. (368 aa)
RIOK2RIO kinase 2. (555 aa)
IRF1Interferon regulatory factor. (315 aa)
IRF6-2Interferon regulatory factor 6. (460 aa)
FOXI1Forkhead box I1. (375 aa)
WRNWRN RecQ like helicase. (1449 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (334 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
FOXF2Forkhead box F2. (405 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (420 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (518 aa)
CDC6Cell division cycle 6. (558 aa)
PLEKUncharacterized protein. (353 aa)
ELF2E74 like ETS transcription factor 2. (595 aa)
DEPDC1BDEP domain containing 1B. (490 aa)
COPS4COP9 signalosome subunit 4. (407 aa)
ETV4ETS variant 4. (453 aa)
DVL1Uncharacterized protein. (698 aa)
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1778 aa)
CUL4BCULLIN_2 domain-containing protein; Belongs to the cullin family. (888 aa)
ADARAdenosine deaminase RNA specific. (1169 aa)
FOXF1Forkhead box F1. (406 aa)
FOXC2Forkhead box C2. (489 aa)
FOXL1Forkhead box L1. (280 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (457 aa)
EIF3MEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (374 aa)
DEPDC7DEP domain containing 7. (526 aa)
ERGETS transcription factor ERG. (486 aa)
ETS2PNT domain-containing protein. (479 aa)
MND1Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (205 aa)
FOXL2Forkhead box L2. (307 aa)
RFX3Regulatory factor X3. (749 aa)
FOXB1Forkhead box B1. (320 aa)
E2F4E2F transcription factor 4. (402 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2015 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (314 aa)
FOXN1Fork-head domain-containing protein. (590 aa)
ARID2Uncharacterized protein. (1798 aa)
ETV5ETS variant 5. (493 aa)
HFM1Helicase for meiosis 1. (1447 aa)
DUSP15-2IRF tryptophan pentad repeat domain-containing protein. (429 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (567 aa)
FOXN4Forkhead box N4. (513 aa)
COPS2COP9 signalosome subunit 2. (450 aa)
COPS3PCI domain-containing protein. (416 aa)
E2F7E2F transcription factor 7. (900 aa)
FOXA2Forkhead box A2. (438 aa)
CDT1Chromatin licensing and DNA replication factor 1. (597 aa)
FOXK1Forkhead box K1. (657 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
METAP2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (481 aa)
ELK3ETS transcription factor ELK3. (414 aa)
GPR155G protein-coupled receptor 155. (866 aa)
DEPDC4DEP domain containing 4. (547 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1653 aa)
CUL4ACullin 4A; Belongs to the cullin family. (936 aa)
LOC100227298H15 domain-containing protein. (223 aa)
TFDP1Transcription factor. (412 aa)
LOC100221426H15 domain-containing protein. (225 aa)
DEPDC5DEP domain-containing protein. (1601 aa)
BLMUncharacterized protein. (1300 aa)
EHFETS homologous factor. (298 aa)
DVL3Dishevelled segment polarity protein 3. (712 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (419 aa)
H1-0H1 histone family member 0. (192 aa)
ASMTLAcetylserotonin O-methyltransferase like. (542 aa)
SHPRHSNF2 histone linker PHD RING helicase. (1693 aa)
FOXI2Forkhead box I2. (428 aa)
RFX4RFX-type winged-helix domain-containing protein. (734 aa)
UBR1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa)
SPICSpi-C transcription factor. (235 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1581 aa)
PLEK2Pleckstrin 2. (355 aa)
E2F5E2F transcription factor 5. (372 aa)
RFX6Regulatory factor X6. (884 aa)
FOXO1Forkhead box O1. (785 aa)
FOXO3Fork-head domain-containing protein. (663 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2207 aa)
RAD21RAD21 cohesin complex component. (631 aa)
GTF2F2Uncharacterized protein. (374 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
E2F6E2F transcription factor 6. (123 aa)
FOXJ2Forkhead box J2. (541 aa)
FOXM1Fork-head domain-containing protein. (775 aa)
GABPAGA binding protein transcription factor subunit alpha. (455 aa)
E2F8E2F transcription factor 8. (896 aa)
SSBPutative Sjogren syndrome antigen B variant 2. (407 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (445 aa)
ELF1E74 like ETS transcription factor 1. (626 aa)
VPS36Vacuolar protein sorting 36 homolog. (375 aa)
LARP7La ribonucleoprotein domain family member 7. (590 aa)
IRF2Interferon regulatory factor. (348 aa)
FOXN3Forkhead box N3. (497 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2006 aa)
LOC100217839HSF_DOMAIN domain-containing protein. (624 aa)
GPS1G protein pathway suppressor 1. (499 aa)
HSF2Heat shock transcription factor 2. (617 aa)
RGS6Regulator of G protein signaling 6. (490 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
LOC100221446Anaphase promoting complex subunit 2; Belongs to the cullin family. (804 aa)
RGS7Regulator of G protein signaling 7. (510 aa)
H0ZAX6_TAEGUUncharacterized protein. (508 aa)
RGS11Regulator of G protein signaling 11. (552 aa)
IRF4Interferon regulatory factor 4. (548 aa)
FOXP1Fork-head domain-containing protein. (700 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1026 aa)
CUL9Cul7 domain-containing protein. (2520 aa)
FOXK2Forkhead box K2. (783 aa)
ETV6ETS variant 6. (750 aa)
FOXP4Forkhead box P4. (679 aa)
DEPTORDEP domain containing MTOR interacting protein. (397 aa)
IRF8Interferon regulatory factor 8. (489 aa)
LOC100224409Uncharacterized protein. (2136 aa)
LARP4BHTH La-type RNA-binding domain-containing protein. (1793 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (866 aa)
FOXN2Forkhead box N2. (437 aa)
LARP4La ribonucleoprotein domain family member 4. (896 aa)
ETV1ETS variant 1. (454 aa)
ELLElongation factor for RNA polymerase II. (610 aa)
RGS9DEP domain-containing protein. (575 aa)
E2F3E2F transcription factor 3. (445 aa)
FOXP2Fork-head domain-containing protein. (711 aa)
ASMTAcetylserotonin O-methyltransferase. (347 aa)
RFX8Uncharacterized protein. (572 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (902 aa)
HP1BP3Heterochromatin protein 1 binding protein 3. (557 aa)
DEPDC1DEP domain containing 1. (1089 aa)
LARP1BHTH La-type RNA-binding domain-containing protein. (1002 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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