STRINGSTRING
SOS1 SOS1 PLCE1 PLCE1 RASGEF1A RASGEF1A RASGEF1C RASGEF1C SH2D3C SH2D3C TIAM2 TIAM2 RALGPS1 RALGPS1 KNDC1 KNDC1 RAPGEF5 RAPGEF5 ARHGEF7 ARHGEF7 RALGDS RALGDS RAPGEF2 RAPGEF2 VAV2 VAV2 RAPGEF4 RAPGEF4 RASGRP1 RASGRP1 MCF2L2 MCF2L2 ARHGEF12 ARHGEF12 RASGRF1 RASGRF1 ARHGEF4 ARHGEF4 ARHGEF3 ARHGEF3 BCAR3 BCAR3 RAPGEF1 RAPGEF1 MCF2L MCF2L ARHGEF11 ARHGEF11 TIAM1 TIAM1 SOS2 SOS2 ARHGEF5 ARHGEF5 PREX2 PREX2 ECT2 ECT2 BCR BCR RASGRP3 RASGRP3 PREX1 PREX1 VAV3 VAV3 RGL1 RGL1 RASGEF1B RASGEF1B MCF2 MCF2 ARHGEF6 ARHGEF6 NET1 NET1 RAPGEF6 RAPGEF6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1322 aa)
PLCE1Phosphoinositide phospholipase C. (2331 aa)
RASGEF1AUncharacterized protein. (527 aa)
RASGEF1CRasGEF domain family member 1C. (481 aa)
SH2D3CSH2 domain containing 3C. (931 aa)
TIAM2DH domain-containing protein. (1725 aa)
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (586 aa)
KNDC1Uncharacterized protein. (1910 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (866 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (803 aa)
RALGDSUncharacterized protein. (830 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1804 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1026 aa)
RASGRP1RAS guanyl releasing protein 1. (792 aa)
MCF2L2MCF.2 cell line derived transforming sequence-like 2. (1283 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1539 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1229 aa)
ARHGEF4Uncharacterized protein. (2247 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (573 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (893 aa)
RAPGEF1Uncharacterized protein. (1232 aa)
MCF2LUncharacterized protein. (1164 aa)
ARHGEF11DH domain-containing protein. (1206 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1604 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
ARHGEF5Uncharacterized protein. (1775 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1581 aa)
ECT2Uncharacterized protein. (985 aa)
BCRUncharacterized protein. (1349 aa)
RASGRP3RAS guanyl releasing protein 3. (692 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1653 aa)
VAV3Vav guanine nucleotide exchange factor 3. (846 aa)
RGL1Ral guanine nucleotide dissociation stimulator like 1. (769 aa)
RASGEF1BRasGEF domain family member 1B. (491 aa)
MCF2MCF.2 cell line derived transforming sequence. (1145 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (738 aa)
NET1Neuroepithelial cell transforming 1. (594 aa)
RAPGEF6Uncharacterized protein. (1468 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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