(46 nodes) G-protein mediated events network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H0Z6A8_TAEGU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (569 aa)
	LOC100220416	Protein kinase domain-containing protein. (382 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	LRBA	Uncharacterized protein. (2855 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	LOC115491787	LOW QUALITY PROTEIN: THAP domain-containing protein 7-like. (312 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV. (397 aa)
	LOC100230245	Uncharacterized protein. (359 aa)
	PLA2G4A	Phospholipase A2. (748 aa)
	PDE1B	PDEase domain-containing protein. (549 aa)
	PDE1C	Phosphodiesterase. (608 aa)
	H1A138_TAEGU	PDEase domain-containing protein. (968 aa)
	ADCY3	Adenylate cyclase 3. (962 aa)
	DCLK1	Uncharacterized protein. (740 aa)
	THAP1	THAP domain containing 1. (244 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1212 aa)
	GNAO1	G protein subunit alpha o1. (384 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (763 aa)
	NBEA	Neurobeachin. (2952 aa)
	GNAI2	G protein subunit alpha i2. (356 aa)
	ADCY8	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1319 aa)
	ADCY6	Guanylate cyclase domain-containing protein. (1156 aa)
	ENSTGUP00000024499	annotation not available (669 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (591 aa)
	ENSTGUP00000023521	annotation not available (507 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
	PDE1A	Phosphodiesterase. (552 aa)
	ENSTGUP00000020893	annotation not available (696 aa)
	PRKACB	Uncharacterized protein; Belongs to the protein kinase superfamily. (398 aa)
	PTRHD1	Uncharacterized protein. (135 aa)
	GNAL	G protein subunit alpha L. (488 aa)
	PRKAR2A	Uncharacterized protein. (399 aa)
	PRKX	Uncharacterized protein; Belongs to the protein kinase superfamily. (364 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1048 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1140 aa)
	PLCB2	Phosphoinositide phospholipase C. (1306 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
	ADCY5	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1216 aa)
	CAMKK1	Calcium/calmodulin dependent protein kinase kinase 1; Belongs to the protein kinase superfamily. (532 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (382 aa)
	ADCY9	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1347 aa)
	GNA11	G protein subunit alpha 11. (359 aa)
	SNX19	Sorting nexin 19. (943 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSTGUP00000007377	ENSTGUP00000007991	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.487
ADCY1	ADCY3	ENSTGUP00000007377	ENSTGUP00000032007	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 3.	0.556
ADCY1	ADCY5	ENSTGUP00000007377	ENSTGUP00000004443	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.476
ADCY1	ADCY6	ENSTGUP00000007377	ENSTGUP00000025657	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein.	0.476
ADCY1	ADCY7	ENSTGUP00000007377	ENSTGUP00000008814	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.499
ADCY1	ADCY8	ENSTGUP00000007377	ENSTGUP00000025787	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.959
ADCY1	ADCY9	ENSTGUP00000007377	ENSTGUP00000004072	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.688
ADCY1	GNAI1	ENSTGUP00000007377	ENSTGUP00000002744	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.813
ADCY1	GNAI2	ENSTGUP00000007377	ENSTGUP00000026853	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.813
ADCY1	GNAI3	ENSTGUP00000007377	ENSTGUP00000001170	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.813
ADCY1	GNAL	ENSTGUP00000007377	ENSTGUP00000010023	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha L.	0.969
ADCY1	GNAO1	ENSTGUP00000007377	ENSTGUP00000030607	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha o1.	0.488
ADCY1	H1A138_TAEGU	ENSTGUP00000007377	ENSTGUP00000033421	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	PDEase domain-containing protein.	0.673
ADCY1	PDE1A	ENSTGUP00000007377	ENSTGUP00000021018	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.673
ADCY1	PDE1C	ENSTGUP00000007377	ENSTGUP00000034758	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.673
ADCY1	PRKACB	ENSTGUP00000007377	ENSTGUP00000018463	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.933
ADCY1	PTRHD1	ENSTGUP00000007377	ENSTGUP00000015512	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.534
ADCY2	ADCY1	ENSTGUP00000007991	ENSTGUP00000007377	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.487
ADCY2	ADCY3	ENSTGUP00000007991	ENSTGUP00000032007	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 3.	0.454
ADCY2	ADCY5	ENSTGUP00000007991	ENSTGUP00000004443	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.693