20 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYK	Tyrosine-protein kinase. (668 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
	SPNS3	Sphingolipid transporter 3 (putative). (498 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (846 aa)
	LOC100226244	Uncharacterized protein. (191 aa)
	LOC100221185	Uncharacterized protein. (738 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	MFSD6	Major facilitator superfamily domain containing 6. (737 aa)
	ENSTGUP00000019987	annotation not available (1587 aa)
	PIK3R2	Uncharacterized protein. (727 aa)
	PIK3CB	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	RHOB	Ras homolog family member B. (196 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (878 aa)
	CLNK	Cytokine-dependent hematopoietic cell linker. (394 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (555 aa)
	H0YWA0_TAEGU	SET domain-containing protein. (1661 aa)
	ENSTGUP00000034337	annotation not available (812 aa)
	CDC42	Cell division cycle 42. (302 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSTGUP00000034337	ENSTGUP00000036310	ENSTGUP00000034337	Cell division cycle 42.	annotation not available	0.686
CDC42	LOC100221185	ENSTGUP00000036310	ENSTGUP00000008408	Cell division cycle 42.	Uncharacterized protein.	0.504
CDC42	LOC100226244	ENSTGUP00000036310	ENSTGUP00000007228	Cell division cycle 42.	Uncharacterized protein.	0.629
CDC42	PDPK1	ENSTGUP00000036310	ENSTGUP00000029735	Cell division cycle 42.	3-phosphoinositide dependent protein kinase 1.	0.482
CDC42	PIK3CA	ENSTGUP00000036310	ENSTGUP00000011093	Cell division cycle 42.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.793
CDC42	PIK3CB	ENSTGUP00000036310	ENSTGUP00000021600	Cell division cycle 42.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.978
CDC42	PIK3R1	ENSTGUP00000036310	ENSTGUP00000003114	Cell division cycle 42.	Phosphoinositide-3-kinase regulatory subunit 1.	0.504
CDC42	PIK3R2	ENSTGUP00000036310	ENSTGUP00000020249	Cell division cycle 42.	Uncharacterized protein.	0.504
CDC42	PLCG2	ENSTGUP00000036310	ENSTGUP00000004589	Cell division cycle 42.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.414
CDC42	RHOB	ENSTGUP00000036310	ENSTGUP00000027521	Cell division cycle 42.	Ras homolog family member B.	0.502
CDC42	VAV2	ENSTGUP00000036310	ENSTGUP00000028131	Cell division cycle 42.	Vav guanine nucleotide exchange factor 2.	0.686
CDC42	VAV3	ENSTGUP00000036310	ENSTGUP00000004903	Cell division cycle 42.	Vav guanine nucleotide exchange factor 3.	0.686
CLNK	PLCG2	ENSTGUP00000029492	ENSTGUP00000004589	Cytokine-dependent hematopoietic cell linker.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.430
ENSTGUP00000034337	CDC42	ENSTGUP00000034337	ENSTGUP00000036310	annotation not available	Cell division cycle 42.	0.686
ENSTGUP00000034337	LOC100226244	ENSTGUP00000034337	ENSTGUP00000007228	annotation not available	Uncharacterized protein.	0.645
ENSTGUP00000034337	PIK3CA	ENSTGUP00000034337	ENSTGUP00000011093	annotation not available	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.422
ENSTGUP00000034337	PLCG2	ENSTGUP00000034337	ENSTGUP00000004589	annotation not available	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.477
ENSTGUP00000034337	RHOB	ENSTGUP00000034337	ENSTGUP00000027521	annotation not available	Ras homolog family member B.	0.522
ENSTGUP00000034337	SYK	ENSTGUP00000034337	ENSTGUP00000000435	annotation not available	Tyrosine-protein kinase.	0.801
LOC100221185	CDC42	ENSTGUP00000008408	ENSTGUP00000036310	Uncharacterized protein.	Cell division cycle 42.	0.504