STRINGSTRING
RRM2B RRM2B ENKUR ENKUR NT5C1A NT5C1A DCK DCK NUDT6 NUDT6 H0YWD7_TAEGU H0YWD7_TAEGU H0YX52_TAEGU H0YX52_TAEGU HPRT1 HPRT1 ATIC ATIC SAMHD1 SAMHD1 TK1 TK1 NT5DC4 NT5DC4 ENTPD3 ENTPD3 UMPS UMPS GLRX2 GLRX2 NUDT16L1 NUDT16L1 NUDT13 NUDT13 ENTPD6 ENTPD6 ADA ADA NT5C3A NT5C3A DPYD DPYD ADPRM ADPRM PNP PNP NRSN1 NRSN1 H0Z9I5_TAEGU H0Z9I5_TAEGU UCKL1 UCKL1 PPAT PPAT APRT APRT AMPD3 AMPD3 DHODH DHODH ADSS2 ADSS2 CMPK1 CMPK1 PUDP PUDP DALRD3 DALRD3 H0ZFS5_TAEGU H0ZFS5_TAEGU ENTPD1 ENTPD1 ENTPD7 ENTPD7 TK2 TK2 LOC100220316 LOC100220316 UPB1 UPB1 ADSL ADSL TYMS TYMS NT5C2 NT5C2 TXNRD1 TXNRD1 GMPS GMPS AK9 AK9 ADSS1 ADSS1 RRM2 RRM2 LOC100224575 LOC100224575 ENSTGUP00000015331 ENSTGUP00000015331 LOC100190573 LOC100190573 PRTFDC1 PRTFDC1 TXNRD3 TXNRD3 DUT DUT ENTPD8 ENTPD8 CEP44 CEP44 GSR GSR SLC25A42 SLC25A42 DCTD DCTD LOC100220427 LOC100220427 NUDT15 NUDT15 AK2 AK2 ENTPD5 ENTPD5 NUDT5 NUDT5 SETBP1 SETBP1 AK7 AK7 UPP1 UPP1 NME2 NME2 PAICS PAICS UCK1 UCK1 ITPA ITPA ADK ADK IMPDH1 IMPDH1 LOC100218564 LOC100218564 NT5DC1 NT5DC1 ENTPD2 ENTPD2 NME8 NME8 NME3 NME3 CTPS2 CTPS2 NUDT1 NUDT1 LOC115496245 LOC115496245 ENSTGUP00000026498 ENSTGUP00000026498 CMPK2 CMPK2 AMPD2 AMPD2 DTYMK DTYMK GART GART PAPOLG PAPOLG TYMP TYMP UPP2 UPP2 ENSTGUP00000029939 ENSTGUP00000029939 NT5E NT5E RRM1 RRM1 IPO13 IPO13 CDA CDA ENSTGUP00000031301 ENSTGUP00000031301 TXN TXN NME1 NME1 SMIM3 SMIM3 ENTPD4 ENTPD4 LOC100229613 LOC100229613 AK6 AK6 AK5 AK5 NT5M NT5M IMPDH2 IMPDH2 CDADC1 CDADC1 ENSTGUP00000033671 ENSTGUP00000033671 ENSTGUP00000035123 ENSTGUP00000035123 ENSTGUP00000035308 ENSTGUP00000035308 AK8 AK8 GMPR GMPR DGUOK DGUOK ENSTGUP00000036805 ENSTGUP00000036805 LOC100229162 LOC100229162 NUDT9 NUDT9 QRICH1 QRICH1 H1A122_TAEGU H1A122_TAEGU GUK1 GUK1 H0YQC2_TAEGU H0YQC2_TAEGU LOC115497664 LOC115497664 GDA GDA CTPS1 CTPS1 AMPD1 AMPD1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (347 aa)
ENKUREnkurin, TRPC channel interacting protein. (419 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (350 aa)
DCKdNK domain-containing protein. (257 aa)
NUDT6Nudix hydrolase 6. (307 aa)
H0YWD7_TAEGUUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (490 aa)
H0YX52_TAEGUUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (265 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (593 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (605 aa)
TK1Thymidine kinase. (223 aa)
NT5DC45'-nucleotidase domain containing 4. (532 aa)
ENTPD3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (531 aa)
UMPSUridine monophosphate synthetase. (481 aa)
GLRX2Glutaredoxin 2. (144 aa)
NUDT16L1Nudix hydrolase 16 like 1. (305 aa)
NUDT13Nudix hydrolase 13. (341 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (442 aa)
ADAAdenosine deaminase. (359 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1017 aa)
ADPRMADP-ribose/CDP-alcohol diphosphatase, manganese dependent. (327 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (324 aa)
NRSN1Neurensin 1. (195 aa)
H0Z9I5_TAEGUThioredoxin domain-containing protein. (158 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (526 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa)
APRTAdenine phosphoribosyltransferase. (177 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (792 aa)
DHODHDHO_dh domain-containing protein. (392 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (463 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (224 aa)
PUDPPseudouridine 5'-phosphatase. (234 aa)
DALRD3DALR anticodon binding domain containing 3. (631 aa)
H0ZFS5_TAEGUUncharacterized protein. (124 aa)
ENTPD1Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (522 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (682 aa)
TK2Thymidine kinase 2. (410 aa)
LOC100220316Adenylate kinase 4, mitochondrial. (244 aa)
UPB1Beta-ureidopropionase 1. (466 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (559 aa)
TYMSThymidylat_synt domain-containing protein. (343 aa)
NT5C2Uncharacterized protein. (592 aa)
TXNRD1Thioredoxin reductase 1. (499 aa)
GMPSGuanine monophosphate synthase. (693 aa)
AK9Uncharacterized protein. (1514 aa)
ADSS1Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (454 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (397 aa)
LOC100224575Uncharacterized protein. (358 aa)
ENSTGUP00000015331annotation not available (252 aa)
LOC100190573SCHIP-1 domain-containing protein. (485 aa)
PRTFDC1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa)
TXNRD3Glutaredoxin domain-containing protein. (654 aa)
DUTDeoxyuridine triphosphatase. (166 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (648 aa)
CEP44Centrosomal protein 44. (626 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (517 aa)
SLC25A42Mitochondrial coenzyme A transporter SLC25A42 isoform X1. (357 aa)
DCTDdCMP deaminase. (380 aa)
LOC100220427dNK domain-containing protein. (270 aa)
NUDT15Nudix hydrolase 15. (165 aa)
AK2Adenylate kinase 2; Belongs to the adenylate kinase family. (246 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (428 aa)
NUDT5Nudix hydrolase 5; Belongs to the Nudix hydrolase family. (217 aa)
SETBP1SET binding protein 1. (1551 aa)
AK7Uncharacterized protein. (726 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (351 aa)
NME2Nucleoside diphosphate kinase. (325 aa)
PAICSAIRC domain-containing protein. (1072 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (214 aa)
ITPAInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (251 aa)
ADKAdenosine kinase. (448 aa)
IMPDH1Inosine monophosphate dehydrogenase 1. (552 aa)
LOC100218564PRK domain-containing protein. (572 aa)
NT5DC15'-nucleotidase domain containing 1. (541 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (505 aa)
NME8NME/NM23 family member 8; Belongs to the NDK family. (574 aa)
NME3Nucleoside diphosphate kinase. (198 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (609 aa)
NUDT1Nudix hydrolase 1; Belongs to the Nudix hydrolase family. (161 aa)
LOC115496245GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (251 aa)
ENSTGUP00000026498annotation not available (357 aa)
CMPK2Cytidine/uridine monophosphate kinase 2. (56 aa)
AMPD2Uncharacterized protein. (819 aa)
DTYMKDeoxythymidylate kinase. (230 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1050 aa)
PAPOLGPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (759 aa)
TYMPThymidine phosphorylase. (462 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (342 aa)
ENSTGUP00000029939annotation not available (387 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (578 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
IPO13Importin 13. (1036 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa)
ENSTGUP00000031301annotation not available (200 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
NME1Nucleoside diphosphate kinase A. (153 aa)
SMIM3Small integral membrane protein 3 isoform X1. (61 aa)
ENTPD4Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (699 aa)
LOC100229613Uncharacterized protein. (373 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (171 aa)
AK5Uncharacterized protein; Belongs to the adenylate kinase family. (566 aa)
NT5MUncharacterized protein. (232 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (538 aa)
CDADC1Cytidine and dCMP deaminase domain containing 1. (520 aa)
ENSTGUP00000033671annotation not available (1331 aa)
ENSTGUP00000035123annotation not available (1072 aa)
ENSTGUP00000035308annotation not available (247 aa)
AK8Uncharacterized protein; Belongs to the adenylate kinase family. (482 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
DGUOKdNK domain-containing protein. (439 aa)
ENSTGUP00000036805annotation not available (274 aa)
LOC100229162Ectonucleoside triphosphate diphosphohydrolase 8. (715 aa)
NUDT9Nudix hydrolase 9. (500 aa)
QRICH1Glutamine rich 1. (779 aa)
H1A122_TAEGUUncharacterized protein. (1371 aa)
GUK1Guanylate kinase 1. (388 aa)
H0YQC2_TAEGUTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1038 aa)
LOC115497664Ribonucleoside-diphosphate reductase large subunit. (801 aa)
GDAGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (493 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (627 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (742 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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