STRINGSTRING
MAPKAPK2 MAPKAPK2 FOS FOS CASP8 CASP8 LOC100226788 LOC100226788 ENSTGUP00000031242 ENSTGUP00000031242 NFKB1 NFKB1 KXD1 KXD1 MAP3K8 MAP3K8 SKP1 SKP1 CD14 CD14 CUL1 CUL1 TRAF2 TRAF2 MAP3K1 MAP3K1 TLR4 TLR4 LRRC45 LRRC45 MAPK11 MAPK11 IKBKB IKBKB MAP2K4 MAP2K4 DUSP7 DUSP7 ENSTGUP00000031367 ENSTGUP00000031367 MAPK1 MAPK1 ATF1 ATF1 TLR7 TLR7 ENSTGUP00000032206 ENSTGUP00000032206 LOC115492392 LOC115492392 LOC100224823 LOC100224823 RPS6KA2 RPS6KA2 FOSL2 FOSL2 MAP3K20 MAP3K20 ENSTGUP00000034342 ENSTGUP00000034342 RELCH RELCH MAP2K6 MAP2K6 CCDC71L CCDC71L CREB5 CREB5 UBE2V1 UBE2V1 ENSTGUP00000035639 ENSTGUP00000035639 MAPK14 MAPK14 MAPK9 MAPK9 LOC115494061 LOC115494061 ENSTGUP00000037662 ENSTGUP00000037662 ENSTGUP00000037953 ENSTGUP00000037953 VRK3 VRK3 UBB UBB TAB3 TAB3 RPS27A RPS27A MAP2K3 MAP2K3 FNBP4 FNBP4 VWC2 VWC2 DUSP6 DUSP6 MAPK8 MAPK8 ATF2 ATF2 TAB1 TAB1 USP14 USP14 IRAK2 IRAK2 TAB2 TAB2 LRRC31 LRRC31 LRRC34 LRRC34 LY96 LY96 PPP4R4 PPP4R4 FBXW11 FBXW11 PPP2R1A PPP2R1A ENSTGUP00000017329 ENSTGUP00000017329 NKIRAS2 NKIRAS2 MAPK10 MAPK10 ENSTGUP00000019325 ENSTGUP00000019325 PPP4R1 PPP4R1 CREM CREM ENSTGUP00000020712 ENSTGUP00000020712 CREB1 CREB1 LOC105759042 LOC105759042 ENSTGUP00000022391 ENSTGUP00000022391 LOC100230816 LOC100230816 ENSTGUP00000022630 ENSTGUP00000022630 MAP3K7 MAP3K7 NFKB2 NFKB2 ENSTGUP00000023897 ENSTGUP00000023897 RPS6KA1 RPS6KA1 TRAF6 TRAF6 ENSTGUP00000025068 ENSTGUP00000025068 NOD1 NOD1 DUSP3 DUSP3 RPS6KA3 RPS6KA3 LOC115492829 LOC115492829 ENSTGUP00000027494 ENSTGUP00000027494 ENSTGUP00000027764 ENSTGUP00000027764 ENSTGUP00000028121 ENSTGUP00000028121 RPS6KA5 RPS6KA5 N4BP1 N4BP1 NKIRAS1 NKIRAS1 MAPKAPK3 MAPKAPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPKAPK2Mitogen-activated protein kinase-activated protein kinase 2. (525 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (370 aa)
CASP8Caspase 8. (480 aa)
LOC100226788Uncharacterized protein. (132 aa)
ENSTGUP00000031242annotation not available (548 aa)
NFKB1Nuclear factor kappa B subunit 1. (982 aa)
KXD1KxDL motif containing 1. (176 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (487 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
CD14Uncharacterized protein. (450 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
TRAF2TNF receptor-associated factor. (486 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1654 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (842 aa)
LRRC45Leucine rich repeat containing 45. (750 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (483 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
ENSTGUP00000031367annotation not available (619 aa)
MAPK1Mitogen-activated protein kinase. (369 aa)
ATF1Activating transcription factor 1. (318 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1047 aa)
ENSTGUP00000032206Leucine-rich repeat-containing protein 14-like. (528 aa)
LOC115492392Leucine-rich repeat-containing protein 14-like. (490 aa)
LOC100224823WRNPLPNID domain-containing protein. (956 aa)
RPS6KA2Non-specific serine/threonine protein kinase. (769 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (323 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (476 aa)
ENSTGUP00000034342annotation not available (394 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1206 aa)
MAP2K6Protein kinase domain-containing protein. (334 aa)
CCDC71LCoiled-coil domain-containing protein 71L. (376 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (148 aa)
ENSTGUP00000035639annotation not available (89 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LOC115494061Leucine-rich repeat-containing protein 14-like. (493 aa)
ENSTGUP00000037662annotation not available (521 aa)
ENSTGUP00000037953annotation not available (153 aa)
VRK3VRK serine/threonine kinase 3. (649 aa)
UBBUbiquitin B. (411 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (630 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (383 aa)
FNBP4Formin binding protein 4. (962 aa)
VWC2Von Willebrand factor C domain containing 2. (331 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
MAPK8Mitogen-activated protein kinase. (401 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (485 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (485 aa)
IRAK2Protein kinase domain-containing protein. (656 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (691 aa)
LRRC31Leucine rich repeat containing 31. (555 aa)
LRRC34Leucine rich repeat containing 34. (423 aa)
LY96Lymphocyte antigen 96. (154 aa)
PPP4R4Uncharacterized protein. (843 aa)
FBXW11Uncharacterized protein. (563 aa)
PPP2R1AUncharacterized protein. (587 aa)
ENSTGUP00000017329annotation not available (580 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
MAPK10Mitogen-activated protein kinase. (472 aa)
ENSTGUP00000019325Uncharacterized protein LOC115492334. (450 aa)
PPP4R1WRNPLPNID domain-containing protein. (1101 aa)
CREMcAMP responsive element modulator. (125 aa)
ENSTGUP00000020712annotation not available (97 aa)
CREB1cAMP responsive element binding protein 1. (324 aa)
LOC105759042Protein kinase domain-containing protein. (559 aa)
ENSTGUP00000022391annotation not available (665 aa)
LOC100230816BZIP domain-containing protein. (480 aa)
ENSTGUP00000022630annotation not available (315 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (627 aa)
NFKB2Nuclear factor kappa B subunit 2. (1122 aa)
ENSTGUP00000023897annotation not available (462 aa)
RPS6KA1Ribosomal protein S6 kinase. (842 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
ENSTGUP00000025068annotation not available (131 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (951 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
LOC115492829Mitogen-activated protein kinase 7-like. (819 aa)
ENSTGUP00000027494annotation not available (338 aa)
ENSTGUP00000027764annotation not available (358 aa)
ENSTGUP00000028121annotation not available (466 aa)
RPS6KA5Ribosomal protein S6 kinase. (784 aa)
N4BP1NEDD4 binding protein 1. (925 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (162 aa)
MAPKAPK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (386 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.