83 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARHGEF38	Uncharacterized protein. (782 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1604 aa)
	ARHGEF17	Rho guanine nucleotide exchange factor 17. (958 aa)
	H0ZTY7_TAEGU	TGc domain-containing protein. (695 aa)
	SQSTM1	Uncharacterized protein. (453 aa)
	ARHGEF11	DH domain-containing protein. (1206 aa)
	ITGB3BP	Integrin subunit beta 3 binding protein. (246 aa)
	MCF2L	Uncharacterized protein. (1164 aa)
	APH1A	Gamma-secretase subunit APH-1A isoform X1. (261 aa)
	FGD3	FYVE, RhoGEF and PH domain containing 3. (917 aa)
	ENSTGUP00000038129	annotation not available (216 aa)
	ENSTGUP00000037953	annotation not available (153 aa)
	ENSTGUP00000037438	annotation not available (333 aa)
	NGFR	Tumor necrosis factor receptor superfamily member 16. (475 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (470 aa)
	TIAM2	DH domain-containing protein. (1725 aa)
	ENSTGUP00000035639	annotation not available (89 aa)
	CCDC71L	Coiled-coil domain-containing protein 71L. (376 aa)
	LINGO1	Leucine rich repeat and Ig domain containing 1. (665 aa)
	ENSTGUP00000034337	annotation not available (812 aa)
	SESTD1	SEC14 and spectrin domain containing 1. (697 aa)
	FGD4	Uncharacterized protein. (1050 aa)
	ARHGEF37	DH domain-containing protein. (729 aa)
	LINGO2	Leucine rich repeat and Ig domain containing 2. (633 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7. (803 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (982 aa)
	ARHGEF3	Rho guanine nucleotide exchange factor 3. (573 aa)
	AKAP13	Uncharacterized protein. (2692 aa)
	KALRN	Uncharacterized protein. (2983 aa)
	ABR	ABR activator of RhoGEF and GTPase. (861 aa)
	ARHGEF10	Rho guanine nucleotide exchange factor 10. (1353 aa)
	ITSN1-2	Intersectin 1. (1725 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (878 aa)
	ARHGEF2	Rho guanine nucleotide exchange factor 2 isoform X3. (1180 aa)
	ARHGEF4	Uncharacterized protein. (2247 aa)
	ENSTGUP00000020764	annotation not available (782 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12. (1539 aa)
	MCF2L2	MCF.2 cell line derived transforming sequence-like 2. (1283 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	ENSTGUP00000024522	annotation not available (197 aa)
	RASGRF2	Uncharacterized protein. (1247 aa)
	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9. (1537 aa)
	FGD2	Uncharacterized protein. (818 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	NET1	Neuroepithelial cell transforming 1. (594 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1322 aa)
	ARHGEF33	DH domain-containing protein. (796 aa)
	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor 6. (738 aa)
	MCF2	MCF.2 cell line derived transforming sequence. (1145 aa)
	PLEKHG5	Pleckstrin homology and RhoGEF domain containing G5. (1107 aa)
	ARHGEF16	Rho guanine nucleotide exchange factor 16. (695 aa)
	ARHGDIA	Rho GDP dissociation inhibitor alpha. (272 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
	NCSTN	Nicastrin. (879 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (846 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
	LOC100224907	TGc domain-containing protein. (689 aa)
	TGM6	TGc domain-containing protein. (704 aa)
	OBSL1	Obscurin-like protein 1. (2263 aa)
	ARHGEF18	Uncharacterized protein. (1515 aa)
	ITSN1	Intersectin 1. (1710 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (238 aa)
	KXD1	KxDL motif containing 1. (176 aa)
	H0YUG4_TAEGU	Uncharacterized protein. (307 aa)
	ARHGEF39	Rho guanine nucleotide exchange factor 39. (441 aa)
	ARHGEF10L	Uncharacterized protein. (1357 aa)
	UBB	Ubiquitin B. (411 aa)
	LOC115496886	Protein kinase domain-containing protein. (554 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	NGEF	Neuronal guanine nucleotide exchange factor. (663 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (2890 aa)
	AATF	Uncharacterized protein. (557 aa)
	MAG	Myelin associated glycoprotein. (541 aa)
	OMG	Oligodendrocyte myelin glycoprotein. (423 aa)
	ECT2	Uncharacterized protein. (985 aa)
	PRDM4	PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (800 aa)
	ARHGEF26	Uncharacterized protein. (875 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (553 aa)
	ARHGEF5	Uncharacterized protein. (1775 aa)
	ADAM17	ADAM metallopeptidase domain 17. (918 aa)
	ENSTGUP00000020504	annotation not available (663 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
	CASP2	Uncharacterized protein; Belongs to the peptidase C14A family. (426 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AATF	RPS27A	ENSTGUP00000008311	ENSTGUP00000007289	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.560
ADAM17	NCSTN	ENSTGUP00000013420	ENSTGUP00000004510	ADAM metallopeptidase domain 17.	Nicastrin.	0.562
ADAM17	NGFR	ENSTGUP00000013420	ENSTGUP00000036482	ADAM metallopeptidase domain 17.	Tumor necrosis factor receptor superfamily member 16.	0.648
AKAP13	ARHGEF16	ENSTGUP00000031172	ENSTGUP00000002885	Uncharacterized protein.	Rho guanine nucleotide exchange factor 16.	0.531
AKAP13	ECT2	ENSTGUP00000031172	ENSTGUP00000011143	Uncharacterized protein.	Uncharacterized protein.	0.474
AKAP13	ITSN1	ENSTGUP00000031172	ENSTGUP00000000534	Uncharacterized protein.	Intersectin 1.	0.472
AKAP13	ITSN1-2	ENSTGUP00000031172	ENSTGUP00000029170	Uncharacterized protein.	Intersectin 1.	0.472
AKAP13	KALRN	ENSTGUP00000031172	ENSTGUP00000030778	Uncharacterized protein.	Uncharacterized protein.	0.416
AKAP13	MCF2	ENSTGUP00000031172	ENSTGUP00000002272	Uncharacterized protein.	MCF.2 cell line derived transforming sequence.	0.443
AKAP13	RPS27A	ENSTGUP00000031172	ENSTGUP00000007289	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.407
AKAP13	TRIO	ENSTGUP00000031172	ENSTGUP00000007697	Uncharacterized protein.	Trio Rho guanine nucleotide exchange factor.	0.416
APH1A	H0YUG4_TAEGU	ENSTGUP00000038690	ENSTGUP00000001932	Gamma-secretase subunit APH-1A isoform X1.	Uncharacterized protein.	0.903
APH1A	NCSTN	ENSTGUP00000038690	ENSTGUP00000004510	Gamma-secretase subunit APH-1A isoform X1.	Nicastrin.	0.957
APH1A	PSEN1	ENSTGUP00000038690	ENSTGUP00000027530	Gamma-secretase subunit APH-1A isoform X1.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.979
APH1A	PSEN2	ENSTGUP00000038690	ENSTGUP00000004463	Gamma-secretase subunit APH-1A isoform X1.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.978
ARHGDIA	NGFR	ENSTGUP00000003610	ENSTGUP00000036482	Rho GDP dissociation inhibitor alpha.	Tumor necrosis factor receptor superfamily member 16.	0.805
ARHGDIA	OMG	ENSTGUP00000003610	ENSTGUP00000008817	Rho GDP dissociation inhibitor alpha.	Oligodendrocyte myelin glycoprotein.	0.410
ARHGEF10	ARHGEF2	ENSTGUP00000030395	ENSTGUP00000027759	Rho guanine nucleotide exchange factor 10.	Rho guanine nucleotide exchange factor 2 isoform X3.	0.504
ARHGEF10	ARHGEF33	ENSTGUP00000030395	ENSTGUP00000002138	Rho guanine nucleotide exchange factor 10.	DH domain-containing protein.	0.547
ARHGEF10	ARHGEF7	ENSTGUP00000030395	ENSTGUP00000032211	Rho guanine nucleotide exchange factor 10.	Rho guanine nucleotide exchange factor 7.	0.459