STRINGSTRING
AP2M1 AP2M1 YES1 YES1 ROCK1 ROCK1 EPHB3 EPHB3 FNDC3B FNDC3B CFL2 CFL2 EPHA7 EPHA7 PAK1 PAK1 ROCK2 ROCK2 EPHA1 EPHA1 TIAM1 TIAM1 EPHA3 EPHA3 EPHA6 EPHA6 CLTC CLTC H0ZWP9_TAEGU H0ZWP9_TAEGU H0Z7P2_TAEGU H0Z7P2_TAEGU EPHA8 EPHA8 H1A4K2_TAEGU H1A4K2_TAEGU MMP9 MMP9 FMN2 FMN2 LOC115492856 LOC115492856 LOC115492856-2 LOC115492856-2 ENSTGUP00000019857 ENSTGUP00000019857 EFNA5 EFNA5 ACTR3B ACTR3B ACTR2 ACTR2 ARPC5L ARPC5L ACTB ACTB EFNA4 EFNA4 CLTCL1 CLTCL1 PTK2 PTK2 ENSTGUP00000024315 ENSTGUP00000024315 ENSTGUP00000024341 ENSTGUP00000024341 EFNB2 EFNB2 EFNA1 EFNA1 ENSTGUP00000024752 ENSTGUP00000024752 LOC115492780 LOC115492780 LYN LYN SDCBP2 SDCBP2 FMN1 FMN1 CLTB CLTB ARPC1B ARPC1B PSEN1 PSEN1 ACTR3 ACTR3 ARPC3 ARPC3 VAV2 VAV2 WASL WASL ENSTGUP00000028627 ENSTGUP00000028627 LOC115491097 LOC115491097 ITSN1-2 ITSN1-2 H1A1H2_TAEGU H1A1H2_TAEGU FNDC3A FNDC3A ACTG1 ACTG1 ENSTGUP00000030506 ENSTGUP00000030506 KALRN KALRN SDC2 SDC2 EPHB6 EPHB6 ARHGEF28 ARHGEF28 ARHGEF7 ARHGEF7 EPHA5 EPHA5 GRIN1 GRIN1 EFNA3 EFNA3 LOC100226209 LOC100226209 SDCBP SDCBP ENSTGUP00000034337 ENSTGUP00000034337 LOC115491115 LOC115491115 CDC42 CDC42 LOC115498343 LOC115498343 LOC100229883-2 LOC100229883-2 CLTA CLTA H0YQ46_TAEGU H0YQ46_TAEGU ITSN1 ITSN1 EFNA2 EFNA2 H0YS29_TAEGU H0YS29_TAEGU RASA1 RASA1 H0YUG4_TAEGU H0YUG4_TAEGU EPHA2 EPHA2 LOC100223640 LOC100223640 EFNB1 EFNB1 ARPC5 ARPC5 PSEN2 PSEN2 NCSTN NCSTN LOC100220716 LOC100220716 VAV3 VAV3 SRC SRC ARPC2 ARPC2 PAK2 PAK2 DSTN DSTN H0Z778_TAEGU H0Z778_TAEGU LOC115491125 LOC115491125 EPHB1 EPHB1 NGEF NGEF MMP2 MMP2 EPHA4 EPHA4 GRIN2B GRIN2B EPHB2 EPHB2 YRDC YRDC LOC100229883 LOC100229883 APH1A APH1A AP2A2 AP2A2 NCK2 NCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AP2M1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
YES1Tyrosine-protein kinase. (541 aa)
ROCK1Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1358 aa)
EPHB3Receptor protein-tyrosine kinase. (991 aa)
FNDC3BFibronectin type III domain containing 3B. (1139 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
EPHA7EPH receptor A7. (1020 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1483 aa)
EPHA1EPH receptor A1. (962 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1604 aa)
EPHA3EPH receptor A3. (937 aa)
EPHA6EPH receptor A6. (965 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
H0ZWP9_TAEGUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (283 aa)
H0Z7P2_TAEGUProtein kinase domain-containing protein. (707 aa)
EPHA8EPH receptor A8. (984 aa)
H1A4K2_TAEGUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (305 aa)
MMP9Matrix metallopeptidase 9. (723 aa)
FMN2FH2 domain-containing protein. (1774 aa)
LOC115492856Adaptor related protein complex 2 subunit sigma 1. (147 aa)
LOC115492856-2AP-2 complex subunit sigma. (185 aa)
ENSTGUP00000019857annotation not available (66 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (418 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (407 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (181 aa)
ACTBUncharacterized protein. (462 aa)
EFNA4Ephrin A4. (228 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
ENSTGUP00000024315annotation not available (176 aa)
ENSTGUP00000024341annotation not available (1431 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (364 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (210 aa)
ENSTGUP00000024752annotation not available (290 aa)
LOC115492780ephrin-B3-like. (259 aa)
LYNTyrosine-protein kinase. (605 aa)
SDCBP2Syndecan binding protein 2. (322 aa)
FMN1Formin 1. (1433 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (209 aa)
ARPC1BActin related protein 2/3 complex subunit 1A. (415 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (426 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (208 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
WASLWASP like actin nucleation promoting factor. (507 aa)
ENSTGUP00000028627annotation not available (369 aa)
LOC115491097Protein kinase domain-containing protein. (709 aa)
ITSN1-2Intersectin 1. (1725 aa)
H1A1H2_TAEGUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (288 aa)
FNDC3AFibronectin type III domain containing 3A. (1181 aa)
ACTG1Actin, cytoplasmic 2. (681 aa)
ENSTGUP00000030506annotation not available (469 aa)
KALRNUncharacterized protein. (2983 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (199 aa)
EPHB6EPH receptor B6. (1000 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1372 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (803 aa)
EPHA5EPH receptor A5. (1020 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (1240 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (348 aa)
LOC100226209Nascent polypeptide-associated complex subunit alpha, muscle-specific form-like isoform X1. (937 aa)
SDCBPSyndecan binding protein. (297 aa)
ENSTGUP00000034337annotation not available (812 aa)
LOC115491115Serine/threonine-protein kinase PAK 3-like isoform X1. (736 aa)
CDC42Cell division cycle 42. (302 aa)
LOC115498343Uncharacterized protein DDB_G0290301-like. (244 aa)
LOC100229883-2Uncharacterized protein. (459 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (246 aa)
H0YQ46_TAEGUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (288 aa)
ITSN1Intersectin 1. (1710 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (199 aa)
H0YS29_TAEGUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (305 aa)
RASA1RAS p21 protein activator 1. (996 aa)
H0YUG4_TAEGUUncharacterized protein. (307 aa)
EPHA2EPH receptor A2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1004 aa)
LOC100223640Uncharacterized protein. (1193 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (374 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
NCSTNNicastrin. (879 aa)
LOC100220716Non-specific serine/threonine protein kinase. (558 aa)
VAV3Vav guanine nucleotide exchange factor 3. (846 aa)
SRCTyrosine-protein kinase. (553 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (308 aa)
PAK2Non-specific serine/threonine protein kinase. (525 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
H0Z778_TAEGUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (440 aa)
LOC115491125Protein kinase domain-containing protein. (642 aa)
EPHB1EPH receptor B1. (1003 aa)
NGEFNeuronal guanine nucleotide exchange factor. (663 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
EPHA4EPH receptor A4. (1011 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1503 aa)
EPHB2EPH receptor B2. (995 aa)
YRDCUncharacterized protein. (1004 aa)
LOC100229883Actin, cytoplasmic type 5. (459 aa)
APH1AGamma-secretase subunit APH-1A isoform X1. (261 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (966 aa)
NCK2NCK adaptor protein 2. (380 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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