48 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAK2	Non-specific serine/threonine protein kinase. (525 aa)
	KRAS	GTPase KRas. (217 aa)
	H1A2F7_TAEGU	DDE Tnp4 domain-containing protein. (459 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	GRAP2	Uncharacterized protein. (296 aa)
	LOC115498405	Fc receptor-like protein 4. (571 aa)
	ENSTGUP00000034337	annotation not available (812 aa)
	ENSTGUP00000034309	annotation not available (177 aa)
	FOSL2	FOS like 2, AP-1 transcription factor subunit. (323 aa)
	ENSTGUP00000033089	annotation not available (140 aa)
	ENSTGUP00000032947	annotation not available (116 aa)
	ENSTGUP00000031367	annotation not available (619 aa)
	ENSTGUP00000030041	Skin secretory protein xP2-like. (153 aa)
	CLNK	Cytokine-dependent hematopoietic cell linker. (394 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (370 aa)
	ENSTGUP00000028778	annotation not available (139 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (878 aa)
	ENSTGUP00000026712	annotation not available (1485 aa)
	ENSTGUP00000024600	annotation not available (156 aa)
	LOC115490876	Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1. (441 aa)
	ENSTGUP00000023558	annotation not available (212 aa)
	H0YUG2_TAEGU	Ig-like domain-containing protein. (259 aa)
	H0ZF58_TAEGU	Uncharacterized protein. (286 aa)
	LOC100222362	Phosphoinositide phospholipase C. (1311 aa)
	ENSTGUP00000020567	annotation not available (104 aa)
	ENSTGUP00000020196	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1. (1281 aa)
	ENSTGUP00000019325	Uncharacterized protein LOC115492334. (450 aa)
	SHC1	SHC adaptor protein 1. (609 aa)
	ENSTGUP00000018548	annotation not available (1396 aa)
	MAPK10	Mitogen-activated protein kinase. (472 aa)
	H1A519_TAEGU	IGv domain-containing protein. (103 aa)
	ENSTGUP00000017069	annotation not available (306 aa)
	HARBI1	Harbinger transposase derived 1. (348 aa)
	HRAS	Putative v-Ha-ras Harvey sarcoma viral oncogene variant 2. (189 aa)
	H0ZF62_TAEGU	Ig-like domain-containing protein. (99 aa)
	GRB2	Putative growth factor receptor-bound protein 2. (217 aa)
	MAPK8	Mitogen-activated protein kinase. (401 aa)
	H0Z793_TAEGU	Uncharacterized protein. (337 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4. (483 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (846 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
	SPNS3	Sphingolipid transporter 3 (putative). (498 aa)
	H0YXS2_TAEGU	Ig-like domain-containing protein. (198 aa)
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1. (1654 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1322 aa)
	NRAS	NRAS proto-oncogene, GTPase. (280 aa)
	CSDE1	Cold shock domain containing E1. (796 aa)
	H0YPH5_TAEGU	Ala_racemase_N domain-containing protein. (925 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLNK	ENSTGUP00000020196	ENSTGUP00000029492	ENSTGUP00000020196	Cytokine-dependent hematopoietic cell linker.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	0.430
CLNK	GRAP2	ENSTGUP00000029492	ENSTGUP00000036174	Cytokine-dependent hematopoietic cell linker.	Uncharacterized protein.	0.499
CLNK	GRB2	ENSTGUP00000029492	ENSTGUP00000008899	Cytokine-dependent hematopoietic cell linker.	Putative growth factor receptor-bound protein 2.	0.499
CLNK	LOC100222362	ENSTGUP00000029492	ENSTGUP00000020950	Cytokine-dependent hematopoietic cell linker.	Phosphoinositide phospholipase C.	0.430
CLNK	PLCG2	ENSTGUP00000029492	ENSTGUP00000004589	Cytokine-dependent hematopoietic cell linker.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.430
CSDE1	GRB2	ENSTGUP00000001009	ENSTGUP00000008899	Cold shock domain containing E1.	Putative growth factor receptor-bound protein 2.	0.639
CSDE1	SOS1	ENSTGUP00000001009	ENSTGUP00000002133	Cold shock domain containing E1.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.703
ENSTGUP00000019325	MAP2K4	ENSTGUP00000019325	ENSTGUP00000006024	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase kinase 4.	0.717
ENSTGUP00000019325	MAP3K1	ENSTGUP00000019325	ENSTGUP00000002666	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase kinase kinase 1.	0.767
ENSTGUP00000019325	MAPK10	ENSTGUP00000019325	ENSTGUP00000018345	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase.	0.800
ENSTGUP00000019325	MAPK8	ENSTGUP00000019325	ENSTGUP00000008391	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase.	0.800
ENSTGUP00000019325	MAPK9	ENSTGUP00000019325	ENSTGUP00000037079	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase.	0.800
ENSTGUP00000020196	CLNK	ENSTGUP00000020196	ENSTGUP00000029492	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Cytokine-dependent hematopoietic cell linker.	0.430
ENSTGUP00000020196	ENSTGUP00000034337	ENSTGUP00000020196	ENSTGUP00000034337	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	annotation not available	0.473
ENSTGUP00000020196	GRAP2	ENSTGUP00000020196	ENSTGUP00000036174	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Uncharacterized protein.	0.741
ENSTGUP00000020196	GRB2	ENSTGUP00000020196	ENSTGUP00000008899	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Putative growth factor receptor-bound protein 2.	0.816
ENSTGUP00000020196	PAK2	ENSTGUP00000020196	ENSTGUP00000006017	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Non-specific serine/threonine protein kinase.	0.426
ENSTGUP00000020196	PLCG2	ENSTGUP00000020196	ENSTGUP00000004589	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.902
ENSTGUP00000020196	SHC1	ENSTGUP00000020196	ENSTGUP00000019228	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	SHC adaptor protein 1.	0.577
ENSTGUP00000020196	SOS1	ENSTGUP00000020196	ENSTGUP00000002133	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.493