32 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VAV3	Vav guanine nucleotide exchange factor 3. (846 aa)
	NFAT5	Nuclear factor of activated T cells 5. (1537 aa)
	GRAP2	Uncharacterized protein. (296 aa)
	LOC115498405	Fc receptor-like protein 4. (571 aa)
	ENSTGUP00000034337	annotation not available (812 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (529 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (553 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
	SPNS3	Sphingolipid transporter 3 (putative). (498 aa)
	H0YXS2_TAEGU	Ig-like domain-containing protein. (198 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1322 aa)
	ITK	Tyrosine-protein kinase. (631 aa)
	TEC	Tyrosine-protein kinase. (630 aa)
	GRB2	Putative growth factor receptor-bound protein 2. (217 aa)
	PPP3CC-2	Serine/threonine-protein phosphatase. (482 aa)
	BTK	Tyrosine-protein kinase. (662 aa)
	H0ZF58_TAEGU	Uncharacterized protein. (286 aa)
	TXK	TXK tyrosine kinase. (546 aa)
	PPP3CC	Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform. (523 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (878 aa)
	ENSTGUP00000030041	Skin secretory protein xP2-like. (153 aa)
	ENSTGUP00000033089	annotation not available (140 aa)
	H0YUG2_TAEGU	Ig-like domain-containing protein. (259 aa)
	LOC100223529	RHD domain-containing protein. (925 aa)
	LOC101232862	RHD_dimer domain-containing protein. (700 aa)
	PPP3R1	Uncharacterized protein. (167 aa)
	WDR92	WD_REPEATS_REGION domain-containing protein. (360 aa)
	NFATC1	Nuclear factor of activated T cells 1. (944 aa)
	SHC1	SHC adaptor protein 1. (609 aa)
	ENSTGUP00000020196	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1. (1281 aa)
	LOC100222362	Phosphoinositide phospholipase C. (1311 aa)
	NFATC3	Nuclear factor of activated T cells 3. (1114 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTK	ENSTGUP00000034337	ENSTGUP00000015504	ENSTGUP00000034337	Tyrosine-protein kinase.	annotation not available	0.590
BTK	GRAP2	ENSTGUP00000015504	ENSTGUP00000036174	Tyrosine-protein kinase.	Uncharacterized protein.	0.735
BTK	GRB2	ENSTGUP00000015504	ENSTGUP00000008899	Tyrosine-protein kinase.	Putative growth factor receptor-bound protein 2.	0.779
BTK	PLCG2	ENSTGUP00000015504	ENSTGUP00000004589	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.719
BTK	SHC1	ENSTGUP00000015504	ENSTGUP00000019228	Tyrosine-protein kinase.	SHC adaptor protein 1.	0.485
BTK	SOS1	ENSTGUP00000015504	ENSTGUP00000002133	Tyrosine-protein kinase.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.558
BTK	VAV2	ENSTGUP00000015504	ENSTGUP00000028131	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 2.	0.590
BTK	VAV3	ENSTGUP00000015504	ENSTGUP00000004903	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 3.	0.590
ENSTGUP00000020196	ENSTGUP00000034337	ENSTGUP00000020196	ENSTGUP00000034337	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	annotation not available	0.473
ENSTGUP00000020196	GRAP2	ENSTGUP00000020196	ENSTGUP00000036174	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Uncharacterized protein.	0.741
ENSTGUP00000020196	GRB2	ENSTGUP00000020196	ENSTGUP00000008899	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Putative growth factor receptor-bound protein 2.	0.816
ENSTGUP00000020196	PLCG2	ENSTGUP00000020196	ENSTGUP00000004589	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.902
ENSTGUP00000020196	PPP3CA	ENSTGUP00000020196	ENSTGUP00000033901	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Serine/threonine-protein phosphatase.	0.902
ENSTGUP00000020196	PPP3CB	ENSTGUP00000020196	ENSTGUP00000007291	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Serine/threonine-protein phosphatase.	0.902
ENSTGUP00000020196	PPP3CC-2	ENSTGUP00000020196	ENSTGUP00000015427	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Serine/threonine-protein phosphatase.	0.902
ENSTGUP00000020196	PPP3R1	ENSTGUP00000020196	ENSTGUP00000017897	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Uncharacterized protein.	0.900
ENSTGUP00000020196	SHC1	ENSTGUP00000020196	ENSTGUP00000019228	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	SHC adaptor protein 1.	0.577
ENSTGUP00000020196	SOS1	ENSTGUP00000020196	ENSTGUP00000002133	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.493
ENSTGUP00000020196	VAV2	ENSTGUP00000020196	ENSTGUP00000028131	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Vav guanine nucleotide exchange factor 2.	0.473
ENSTGUP00000020196	VAV3	ENSTGUP00000020196	ENSTGUP00000004903	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.	Vav guanine nucleotide exchange factor 3.	0.473