53 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EPHA4	EPH receptor A4. (1011 aa)
	APH1A	Gamma-secretase subunit APH-1A isoform X1. (261 aa)
	LOC100229883	Actin, cytoplasmic type 5. (459 aa)
	YRDC	Uncharacterized protein. (1004 aa)
	EPHB2	EPH receptor B2. (995 aa)
	LOC100229883-2	Uncharacterized protein. (459 aa)
	ENSTGUP00000034337	annotation not available (812 aa)
	EFNA3	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (348 aa)
	EPHA5	EPH receptor A5. (1020 aa)
	EPHB6	EPH receptor B6. (1000 aa)
	ACTG1	Actin, cytoplasmic 2. (681 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1181 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (878 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	CLTB	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (209 aa)
	LYN	Tyrosine-protein kinase. (605 aa)
	LOC115492780	ephrin-B3-like. (259 aa)
	ENSTGUP00000024752	annotation not available (290 aa)
	EFNA1	Ephrin A1; Belongs to the ephrin family. (210 aa)
	EFNB2	Ephrin B2; Belongs to the ephrin family. (364 aa)
	ENSTGUP00000024341	annotation not available (1431 aa)
	ENSTGUP00000024315	annotation not available (176 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	ACTB	Uncharacterized protein. (462 aa)
	EFNA5	Ephrin A5; Belongs to the ephrin family. (228 aa)
	ENSTGUP00000019857	annotation not available (66 aa)
	LOC115492856-2	AP-2 complex subunit sigma. (185 aa)
	LOC115492856	Adaptor related protein complex 2 subunit sigma 1. (147 aa)
	MMP9	Matrix metallopeptidase 9. (723 aa)
	EPHA8	EPH receptor A8. (984 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
	EPHA6	EPH receptor A6. (965 aa)
	EPHA3	EPH receptor A3. (937 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1604 aa)
	EPHA1	EPH receptor A1. (962 aa)
	EPHA7	EPH receptor A7. (1020 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1139 aa)
	EPHB3	Receptor protein-tyrosine kinase. (991 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	AP2M1	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (966 aa)
	MMP2	Matrix metallopeptidase 2. (661 aa)
	EPHB1	EPH receptor B1. (1003 aa)
	SRC	Tyrosine-protein kinase. (553 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (846 aa)
	NCSTN	Nicastrin. (879 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
	EFNB1	Ephrin B1; Belongs to the ephrin family. (374 aa)
	LOC100223640	Uncharacterized protein. (1193 aa)
	EPHA2	EPH receptor A2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1004 aa)
	H0YUG4_TAEGU	Uncharacterized protein. (307 aa)
	EFNA2	Ephrin A2; Belongs to the ephrin family. (199 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (246 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTG1	ENSTGUP00000023808	ENSTGUP00000030258	Uncharacterized protein.	Actin, cytoplasmic 2.	0.901
ACTB	LOC100229883-2	ENSTGUP00000023808	ENSTGUP00000037065	Uncharacterized protein.	Uncharacterized protein.	0.901
ACTG1	ACTB	ENSTGUP00000030258	ENSTGUP00000023808	Actin, cytoplasmic 2.	Uncharacterized protein.	0.901
ACTG1	LOC100229883-2	ENSTGUP00000030258	ENSTGUP00000037065	Actin, cytoplasmic 2.	Uncharacterized protein.	0.901
AP2A2	AP2M1	ENSTGUP00000010025	ENSTGUP00000010457	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.993
AP2A2	CLTA	ENSTGUP00000010025	ENSTGUP00000000118	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.722
AP2A2	CLTB	ENSTGUP00000010025	ENSTGUP00000026120	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.584
AP2A2	CLTC	ENSTGUP00000010025	ENSTGUP00000014958	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.721
AP2A2	CLTCL1	ENSTGUP00000010025	ENSTGUP00000024164	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.721
AP2A2	LOC115492856	ENSTGUP00000010025	ENSTGUP00000019021	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Adaptor related protein complex 2 subunit sigma 1.	0.995
AP2A2	LOC115492856-2	ENSTGUP00000010025	ENSTGUP00000019683	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-2 complex subunit sigma.	0.953
AP2M1	AP2A2	ENSTGUP00000010457	ENSTGUP00000010025	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.993
AP2M1	CLTA	ENSTGUP00000010457	ENSTGUP00000000118	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.862
AP2M1	CLTB	ENSTGUP00000010457	ENSTGUP00000026120	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.793
AP2M1	CLTC	ENSTGUP00000010457	ENSTGUP00000014958	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.885
AP2M1	CLTCL1	ENSTGUP00000010457	ENSTGUP00000024164	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.885
AP2M1	LOC115492856	ENSTGUP00000010457	ENSTGUP00000019021	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	Adaptor related protein complex 2 subunit sigma 1.	0.981
AP2M1	LOC115492856-2	ENSTGUP00000010457	ENSTGUP00000019683	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit sigma.	0.971
APH1A	ENSTGUP00000019857	ENSTGUP00000038690	ENSTGUP00000019857	Gamma-secretase subunit APH-1A isoform X1.	annotation not available	0.950
APH1A	H0YUG4_TAEGU	ENSTGUP00000038690	ENSTGUP00000001932	Gamma-secretase subunit APH-1A isoform X1.	Uncharacterized protein.	0.903