STRINGSTRING
HGF HGF SH3GL2 SH3GL2 MET MET UBB UBB RPS27A RPS27A SH3KBP1 SH3KBP1 GRB2 GRB2 LOC100227679 LOC100227679 PTPRJ PTPRJ LRIG1 LRIG1 CD2AP CD2AP PTPN1 PTPN1 STAM2 STAM2 STAM STAM SH3GL1 SH3GL1 PTPN2 PTPN2 SH3GL3 SH3GL3 HGS HGS CBL CBL USP8 USP8 EPS15 EPS15 ENSTGUP00000035639 ENSTGUP00000035639 ENSTGUP00000037953 ENSTGUP00000037953
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1385 aa)
UBBUbiquitin B. (411 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (704 aa)
GRB2Putative growth factor receptor-bound protein 2. (217 aa)
LOC100227679Tyrosine-protein phosphatase non-receptor type. (432 aa)
PTPRJUncharacterized protein. (1335 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1213 aa)
CD2APCD2 associated protein. (637 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type 1. (432 aa)
STAM2Signal transducing adaptor molecule 2. (506 aa)
STAMSignal transducing adaptor molecule. (532 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (367 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (420 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (373 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (897 aa)
CBLUncharacterized protein. (871 aa)
USP8Uncharacterized protein; Belongs to the peptidase C19 family. (1115 aa)
EPS15Uncharacterized protein. (933 aa)
ENSTGUP00000035639annotation not available (89 aa)
ENSTGUP00000037953annotation not available (153 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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