STRINGSTRING
SOS2 SOS2 USP2 USP2 ARHGEF18 ARHGEF18 ITSN1 ITSN1 NGF NGF KXD1 KXD1 OTUD1 OTUD1 UBE2D2 UBE2D2 H0YUG4_TAEGU H0YUG4_TAEGU ARHGEF39 ARHGEF39 NET1 NET1 SOS1 SOS1 ARHGEF33 ARHGEF33 ARHGEF6 ARHGEF6 MCF2 MCF2 TRAF2 TRAF2 PLEKHG5 PLEKHG5 WDR31 WDR31 ARHGEF16 ARHGEF16 ARHGDIA ARHGDIA UBE2D3 UBE2D3 PSEN2 PSEN2 NCSTN NCSTN OTUD7B OTUD7B VAV3 VAV3 UBE2D1 UBE2D1 IKBKB IKBKB LOC100224907 LOC100224907 TGM6 TGM6 TMEM198 TMEM198 OBSL1 OBSL1 TBK1 TBK1 TRAF1 TRAF1 CASP3 CASP3 USP4 USP4 UBB UBB LOC115496886 LOC115496886 SMPD3 SMPD3 RPS27A RPS27A ULK2 ULK2 NGEF NGEF OTULINL OTULINL TRIO TRIO CYLD CYLD ULK1 ULK1 AATF AATF OMG OMG SPATA2 SPATA2 LOC100231625 LOC100231625 LOC100223333 LOC100223333 CASP10 CASP10 ECT2 ECT2 TNFSF10 TNFSF10 TNFAIP3 TNFAIP3 PRDM4 PRDM4 NSMAF NSMAF ARHGEF26 ARHGEF26 RIPK2 RIPK2 ARHGEF5 ARHGEF5 BIRC2 BIRC2 H0ZR88_TAEGU H0ZR88_TAEGU ADAM17 ADAM17 CASP2 CASP2 ARHGEF38 ARHGEF38 TNFRSF1A TNFRSF1A TIAM1 TIAM1 ARHGEF17 ARHGEF17 H0ZTY7_TAEGU H0ZTY7_TAEGU SQSTM1 SQSTM1 FASLG FASLG ARHGEF11 ARHGEF11 ITGB3BP ITGB3BP STUB1 STUB1 MCF2L MCF2L TRADD TRADD SPPL2A SPPL2A MAG MAG ENSTGUP00000020504 ENSTGUP00000020504 ARHGEF3 ARHGEF3 ARHGEF4 ARHGEF4 ENSTGUP00000020764 ENSTGUP00000020764 LOC115498199 LOC115498199 FAS FAS CFLAR CFLAR IKBKE IKBKE ARHGEF12 ARHGEF12 ENSTGUP00000022855 ENSTGUP00000022855 SMPD2 SMPD2 OPTN OPTN TAX1BP1 TAX1BP1 MCF2L2 MCF2L2 TRAF6 TRAF6 ENSTGUP00000024330 ENSTGUP00000024330 ENSTGUP00000024522 ENSTGUP00000024522 CLIP4 CLIP4 RBCK1 RBCK1 RASGRF2 RASGRF2 ARHGEF9 ARHGEF9 USP21 USP21 ENSTGUP00000026997 ENSTGUP00000026997 FGD2 FGD2 MIB2 MIB2 PSEN1 PSEN1 ARHGEF10L ARHGEF10L ARHGEF2 ARHGEF2 VAV2 VAV2 ITSN1-2 ITSN1-2 MAPKAPK2 MAPKAPK2 BAG4 BAG4 CASP8 CASP8 ARHGEF10 ARHGEF10 ABR ABR KALRN KALRN AKAP13 AKAP13 ENSTGUP00000031242 ENSTGUP00000031242 NFKB1 NFKB1 XIAP XIAP BIRC7 BIRC7 ARHGEF7 ARHGEF7 SHARPIN SHARPIN LINGO2 LINGO2 SPPL2B SPPL2B ARHGEF37 ARHGEF37 RIPK1 RIPK1 MAP3K20 MAP3K20 FGD4 FGD4 SESTD1 SESTD1 LOC100223666 LOC100223666 ENSTGUP00000034337 ENSTGUP00000034337 ENSTGUP00000034342 ENSTGUP00000034342 LINGO1 LINGO1 FADD FADD CCDC71L CCDC71L LOC115494026 LOC115494026 ENSTGUP00000035639 ENSTGUP00000035639 TIAM2 TIAM2 PRKCI PRKCI NGFR NGFR LOC115495264 LOC115495264 ENSTGUP00000037438 ENSTGUP00000037438 ENSTGUP00000037953 ENSTGUP00000037953 ENSTGUP00000038129 ENSTGUP00000038129 FGD3 FGD3 APH1A APH1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
USP2Ubiquitin carboxyl-terminal hydrolase. (577 aa)
ARHGEF18Uncharacterized protein. (1515 aa)
ITSN1Intersectin 1. (1710 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (238 aa)
KXD1KxDL motif containing 1. (176 aa)
OTUD1OTU deubiquitinase 1. (429 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
H0YUG4_TAEGUUncharacterized protein. (307 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (441 aa)
NET1Neuroepithelial cell transforming 1. (594 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1322 aa)
ARHGEF33DH domain-containing protein. (796 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (738 aa)
MCF2MCF.2 cell line derived transforming sequence. (1145 aa)
TRAF2TNF receptor-associated factor. (486 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1107 aa)
WDR31WD_REPEATS_REGION domain-containing protein. (343 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (695 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (272 aa)
UBE2D3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (155 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
NCSTNNicastrin. (879 aa)
OTUD7BOTU deubiquitinase 7B. (857 aa)
VAV3Vav guanine nucleotide exchange factor 3. (846 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
LOC100224907TGc domain-containing protein. (689 aa)
TGM6TGc domain-containing protein. (704 aa)
TMEM198Transmembrane protein 198. (402 aa)
OBSL1Obscurin-like protein 1. (2263 aa)
TBK1TANK binding kinase 1. (729 aa)
TRAF1TNF receptor-associated factor. (553 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (282 aa)
USP4Ubiquitin carboxyl-terminal hydrolase. (950 aa)
UBBUbiquitin B. (411 aa)
LOC115496886Protein kinase domain-containing protein. (554 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (660 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ULK2Protein kinase domain-containing protein. (1076 aa)
NGEFNeuronal guanine nucleotide exchange factor. (663 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (369 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (2890 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1103 aa)
AATFUncharacterized protein. (557 aa)
OMGOligodendrocyte myelin glycoprotein. (423 aa)
SPATA2Spermatogenesis associated 2. (523 aa)
LOC100231625TNFR-Cys domain-containing protein. (308 aa)
LOC100223333Caspase 8. (459 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (475 aa)
ECT2Uncharacterized protein. (985 aa)
TNFSF10TNF superfamily member 10; Belongs to the tumor necrosis factor family. (424 aa)
TNFAIP3TNF alpha induced protein 3. (804 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (800 aa)
NSMAFNeutral sphingomyelinase activation associated factor. (1019 aa)
ARHGEF26Uncharacterized protein. (875 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (553 aa)
ARHGEF5Uncharacterized protein. (1775 aa)
BIRC2Uncharacterized protein. (598 aa)
H0ZR88_TAEGUUncharacterized protein. (743 aa)
ADAM17ADAM metallopeptidase domain 17. (918 aa)
CASP2Uncharacterized protein; Belongs to the peptidase C14A family. (426 aa)
ARHGEF38Uncharacterized protein. (782 aa)
TNFRSF1AUncharacterized protein. (429 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1604 aa)
ARHGEF17Rho guanine nucleotide exchange factor 17. (958 aa)
H0ZTY7_TAEGUTGc domain-containing protein. (695 aa)
SQSTM1Uncharacterized protein. (453 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
ARHGEF11DH domain-containing protein. (1206 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (246 aa)
STUB1STIP1 homology and U-box containing protein 1. (313 aa)
MCF2LUncharacterized protein. (1164 aa)
TRADDTNFRSF1A associated via death domain. (409 aa)
SPPL2ASignal peptide peptidase like 2A. (563 aa)
MAGMyelin associated glycoprotein. (541 aa)
ENSTGUP00000020504annotation not available (663 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (573 aa)
ARHGEF4Uncharacterized protein. (2247 aa)
ENSTGUP00000020764annotation not available (782 aa)
LOC115498199Uncharacterized protein. (373 aa)
FASUncharacterized protein. (363 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (484 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (757 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1539 aa)
ENSTGUP00000022855annotation not available (584 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (500 aa)
OPTNOptineurin. (551 aa)
TAX1BP1Tax1 binding protein 1. (834 aa)
MCF2L2MCF.2 cell line derived transforming sequence-like 2. (1283 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
ENSTGUP00000024330annotation not available (343 aa)
ENSTGUP00000024522annotation not available (197 aa)
CLIP4CAP-Gly domain containing linker protein family member 4. (699 aa)
RBCK1RanBP-type and C3HC4-type zinc finger-containing protein 1. (333 aa)
RASGRF2Uncharacterized protein. (1247 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (1537 aa)
USP21Ubiquitin specific peptidase 21. (603 aa)
ENSTGUP00000026997annotation not available (687 aa)
FGD2Uncharacterized protein. (818 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (952 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ARHGEF10LUncharacterized protein. (1357 aa)
ARHGEF2Rho guanine nucleotide exchange factor 2 isoform X3. (1180 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
ITSN1-2Intersectin 1. (1725 aa)
MAPKAPK2Mitogen-activated protein kinase-activated protein kinase 2. (525 aa)
BAG4Uncharacterized protein. (340 aa)
CASP8Caspase 8. (480 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1353 aa)
ABRABR activator of RhoGEF and GTPase. (861 aa)
KALRNUncharacterized protein. (2983 aa)
AKAP13Uncharacterized protein. (2692 aa)
ENSTGUP00000031242annotation not available (548 aa)
NFKB1Nuclear factor kappa B subunit 1. (982 aa)
XIAPX-linked inhibitor of apoptosis. (495 aa)
BIRC7Baculoviral IAP repeat containing 7. (426 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (803 aa)
SHARPINSHANK associated RH domain interactor. (380 aa)
LINGO2Leucine rich repeat and Ig domain containing 2. (633 aa)
SPPL2BSignal peptide peptidase like 2B. (772 aa)
ARHGEF37DH domain-containing protein. (729 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (476 aa)
FGD4Uncharacterized protein. (1050 aa)
SESTD1SEC14 and spectrin domain containing 1. (697 aa)
LOC100223666TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (333 aa)
ENSTGUP00000034337annotation not available (812 aa)
ENSTGUP00000034342annotation not available (394 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (665 aa)
FADDFas associated via death domain. (221 aa)
CCDC71LCoiled-coil domain-containing protein 71L. (376 aa)
LOC115494026Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1. (786 aa)
ENSTGUP00000035639annotation not available (89 aa)
TIAM2DH domain-containing protein. (1725 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (470 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (475 aa)
LOC115495264Tumor necrosis factor ligand superfamily member 10-like. (333 aa)
ENSTGUP00000037438annotation not available (333 aa)
ENSTGUP00000037953annotation not available (153 aa)
ENSTGUP00000038129annotation not available (216 aa)
FGD3FYVE, RhoGEF and PH domain containing 3. (917 aa)
APH1AGamma-secretase subunit APH-1A isoform X1. (261 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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