5 items (Taeniopygia guttata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	GAB1	GRB2 associated binding protein 1. (720 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa)
	MET	MET proto-oncogene, receptor tyrosine kinase. (1385 aa)
	GRB2	Putative growth factor receptor-bound protein 2. (217 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAB1	GRB2	ENSTGUP00000002472	ENSTGUP00000008899	GRB2 associated binding protein 1.	Putative growth factor receptor-bound protein 2.	0.997
GAB1	HGF	ENSTGUP00000002472	ENSTGUP00000002672	GRB2 associated binding protein 1.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.741
GAB1	MET	ENSTGUP00000002472	ENSTGUP00000005389	GRB2 associated binding protein 1.	MET proto-oncogene, receptor tyrosine kinase.	0.991
GAB1	PIK3CA	ENSTGUP00000002472	ENSTGUP00000011093	GRB2 associated binding protein 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.610
GRB2	GAB1	ENSTGUP00000008899	ENSTGUP00000002472	Putative growth factor receptor-bound protein 2.	GRB2 associated binding protein 1.	0.997
GRB2	HGF	ENSTGUP00000008899	ENSTGUP00000002672	Putative growth factor receptor-bound protein 2.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.626
GRB2	MET	ENSTGUP00000008899	ENSTGUP00000005389	Putative growth factor receptor-bound protein 2.	MET proto-oncogene, receptor tyrosine kinase.	0.982
GRB2	PIK3CA	ENSTGUP00000008899	ENSTGUP00000011093	Putative growth factor receptor-bound protein 2.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.713
HGF	GAB1	ENSTGUP00000002672	ENSTGUP00000002472	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	GRB2 associated binding protein 1.	0.741
HGF	GRB2	ENSTGUP00000002672	ENSTGUP00000008899	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Putative growth factor receptor-bound protein 2.	0.626
HGF	MET	ENSTGUP00000002672	ENSTGUP00000005389	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	MET proto-oncogene, receptor tyrosine kinase.	0.996
HGF	PIK3CA	ENSTGUP00000002672	ENSTGUP00000011093	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.588
MET	GAB1	ENSTGUP00000005389	ENSTGUP00000002472	MET proto-oncogene, receptor tyrosine kinase.	GRB2 associated binding protein 1.	0.991
MET	GRB2	ENSTGUP00000005389	ENSTGUP00000008899	MET proto-oncogene, receptor tyrosine kinase.	Putative growth factor receptor-bound protein 2.	0.982
MET	HGF	ENSTGUP00000005389	ENSTGUP00000002672	MET proto-oncogene, receptor tyrosine kinase.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.996
MET	PIK3CA	ENSTGUP00000005389	ENSTGUP00000011093	MET proto-oncogene, receptor tyrosine kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.895
PIK3CA	GAB1	ENSTGUP00000011093	ENSTGUP00000002472	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	GRB2 associated binding protein 1.	0.610
PIK3CA	GRB2	ENSTGUP00000011093	ENSTGUP00000008899	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Putative growth factor receptor-bound protein 2.	0.713
PIK3CA	HGF	ENSTGUP00000011093	ENSTGUP00000002672	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.588
PIK3CA	MET	ENSTGUP00000011093	ENSTGUP00000005389	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	MET proto-oncogene, receptor tyrosine kinase.	0.895