Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
E2F2
E2F transcription factor 2. (450 aa)
E2F4
E2F transcription factor 4. (402 aa)
E2F5
E2F transcription factor 5. (372 aa)
E2F1
E2F transcription factor 1. (375 aa)
E2F3
E2F transcription factor 3. (445 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729 Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch