node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | ESR1 | ENSTGUP00000033723 | ENSTGUP00000011604 | Uncharacterized protein. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. | 0.564 |
ALB | INS | ENSTGUP00000033723 | ENSTGUP00000009610 | Uncharacterized protein. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.724 |
ALB | MMP9 | ENSTGUP00000033723 | ENSTGUP00000018561 | Uncharacterized protein. | Matrix metallopeptidase 9. | 0.411 |
AQP4 | MBP | ENSTGUP00000020655 | ENSTGUP00000033146 | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Myelin basic protein. | 0.424 |
BDNF | ESR1 | ENSTGUP00000022002 | ENSTGUP00000011604 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. | 0.473 |
BDNF | IGF2 | ENSTGUP00000022002 | ENSTGUP00000009618 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | IlGF domain-containing protein. | 0.421 |
BDNF | INS | ENSTGUP00000022002 | ENSTGUP00000009610 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.567 |
BDNF | MMP9 | ENSTGUP00000022002 | ENSTGUP00000018561 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Matrix metallopeptidase 9. | 0.495 |
ESR1 | ALB | ENSTGUP00000011604 | ENSTGUP00000033723 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. | Uncharacterized protein. | 0.564 |
ESR1 | BDNF | ENSTGUP00000011604 | ENSTGUP00000022002 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | 0.473 |
ESR1 | HIF1A | ENSTGUP00000011604 | ENSTGUP00000013365 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. | Hypoxia inducible factor 1 subunit alpha. | 0.514 |
ESR1 | INS | ENSTGUP00000011604 | ENSTGUP00000009610 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.557 |
ESR1 | MMP9 | ENSTGUP00000011604 | ENSTGUP00000018561 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. | Matrix metallopeptidase 9. | 0.521 |
GSK3B | INS | ENSTGUP00000013775 | ENSTGUP00000009610 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.581 |
GSK3B | MTOR | ENSTGUP00000013775 | ENSTGUP00000002370 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. | 0.449 |
GSK3B | TSC2 | ENSTGUP00000013775 | ENSTGUP00000021638 | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | TSC complex subunit 2. | 0.965 |
HIF1A | ESR1 | ENSTGUP00000013365 | ENSTGUP00000011604 | Hypoxia inducible factor 1 subunit alpha. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. | 0.514 |
IGF2 | BDNF | ENSTGUP00000009618 | ENSTGUP00000022002 | IlGF domain-containing protein. | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | 0.421 |
IGF2 | IGFBP1 | ENSTGUP00000009618 | ENSTGUP00000007382 | IlGF domain-containing protein. | Insulin like growth factor binding protein 1. | 0.894 |
IGF2 | IGFBP2 | ENSTGUP00000009618 | ENSTGUP00000024514 | IlGF domain-containing protein. | Insulin like growth factor binding protein 2. | 0.869 |