(27 nodes) (2018) Identification and characterization of skin color microRNAs in Koi carp (Cyprinus carpio L.) by Illumina sequencing. network (Taeniopygia guttata)

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
	FGF22	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (150 aa)
	EGFR	Receptor protein-tyrosine kinase. (1222 aa)
	FGF13	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (453 aa)
	TYRP1	Tyrosinase related protein 1. (536 aa)
	FGF20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	KIT	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	MC1R	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (314 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	FGF14	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
	TYR	Tyrosinase. (537 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (527 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	FOXD3	Forkhead box protein D3. (401 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
	FGF19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
	DKK1	Dickkopf WNT signaling pathway inhibitor 1. (263 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (226 aa)
	FGF5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
	SOX10	SRY-box transcription factor 10. (591 aa)
	FGF3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
	FGF12	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
	FGF16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	FGF1	ENSTGUP00000001863	ENSTGUP00000000159	Receptor protein-tyrosine kinase.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.702
EGFR	FGF10	ENSTGUP00000001863	ENSTGUP00000029603	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.685
EGFR	FGF16	ENSTGUP00000001863	ENSTGUP00000006053	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.703
EGFR	FGF18	ENSTGUP00000001863	ENSTGUP00000015072	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.747
EGFR	FGF19	ENSTGUP00000001863	ENSTGUP00000025874	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.675
EGFR	FGF2	ENSTGUP00000001863	ENSTGUP00000024422	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.756
EGFR	FGF20	ENSTGUP00000001863	ENSTGUP00000007521	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.703
EGFR	FGF3	ENSTGUP00000001863	ENSTGUP00000005531	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.690
EGFR	FGF5	ENSTGUP00000001863	ENSTGUP00000035530	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.690
EGFR	FGF6	ENSTGUP00000001863	ENSTGUP00000012630	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.693
EGFR	FGF7	ENSTGUP00000001863	ENSTGUP00000019495	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.692
EGFR	FGF8	ENSTGUP00000001863	ENSTGUP00000010279	Receptor protein-tyrosine kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.689
FGF1	EGFR	ENSTGUP00000000159	ENSTGUP00000001863	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Receptor protein-tyrosine kinase.	0.702
FGF1	FGF10	ENSTGUP00000000159	ENSTGUP00000029603	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.664
FGF1	FGF18	ENSTGUP00000000159	ENSTGUP00000015072	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.605
FGF1	FGF19	ENSTGUP00000000159	ENSTGUP00000025874	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.508
FGF1	FGF22	ENSTGUP00000000159	ENSTGUP00000000636	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.498
FGF1	FGF3	ENSTGUP00000000159	ENSTGUP00000005531	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.520
FGF1	FGF5	ENSTGUP00000000159	ENSTGUP00000035530	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.473
FGF1	FGF6	ENSTGUP00000000159	ENSTGUP00000012630	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.420