STRINGSTRING
HOXA11 HOXA11 PITX1 PITX1 DLX5 DLX5 HGF HGF PITX2 PITX2 EPHA4 EPHA4 PAX3 PAX3 TBX4 TBX4 HOXD11 HOXD11 TBX5 TBX5 CXCR4 CXCR4 OSR2 OSR2 MYF5 MYF5 WT1 WT1 EFNA5 EFNA5 GATA4 GATA4 OSR1 OSR1 BMP4 BMP4 FAT1 FAT1 PDGFRA PDGFRA SCX SCX LHX2 LHX2 MYOG MYOG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXA11Homeobox A11. (298 aa)
PITX1Homeobox protein. (302 aa)
DLX5Distal-less homeobox 5. (290 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa)
PITX2Homeobox protein. (360 aa)
EPHA4EPH receptor A4. (1011 aa)
PAX3Paired box 3. (484 aa)
TBX4T-box transcription factor 4. (554 aa)
HOXD11Homeobox domain-containing protein. (280 aa)
TBX5T-box transcription factor 5. (542 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (446 aa)
OSR2Odd-skipped related transciption factor 2. (311 aa)
MYF5Myogenic factor. (298 aa)
WT1WT1 transcription factor. (414 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
GATA4GATA binding protein 4. (412 aa)
OSR1Protein odd-skipped-related 1. (260 aa)
BMP4Bone morphogenetic protein 4. (420 aa)
FAT1FAT atypical cadherin 1. (4457 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1109 aa)
SCXBasic helix-loop-helix transcription factor scleraxis. (197 aa)
LHX2LIM homeobox 2. (435 aa)
MYOGMyogenin. (270 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (18%) [HD]