(53 nodes) (2019) Molecular architecture of the zebra finch arcopallium. network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAMK2N1	Calcium/calmodulin-dependent protein kinase II inhibitor 1. (237 aa)
	UTS2B	Urotensin 2B. (127 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (621 aa)
	FABP7	Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	GAD2	Glutamate decarboxylase 2. (574 aa)
	C1QL3	Complement C1q like 3. (255 aa)
	GRIK3	Uncharacterized protein. (919 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	AR	Androgen receptor. (684 aa)
	CAMKK1	Calcium/calmodulin dependent protein kinase kinase 1; Belongs to the protein kinase superfamily. (532 aa)
	SLC24A2	Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (650 aa)
	KCND2	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (632 aa)
	KCNS1	Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (568 aa)
	NECAB2	N-terminal EF-hand calcium binding protein 2. (386 aa)
	CYP19A1	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (509 aa)
	SCUBE2	Signal peptide, CUB domain and EGF like domain containing 2. (899 aa)
	SV2B	Synaptic vesicle glycoprotein 2B. (671 aa)
	CBLN2	Cerebellin 2 precursor. (228 aa)
	LHX5	LIM homeobox 5. (420 aa)
	RGS4	Regulator of G protein signaling 4. (225 aa)
	SCUBE1	Signal peptide, CUB domain and EGF like domain containing 1. (1018 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (895 aa)
	ETV1	ETS variant 1. (454 aa)
	FOSL2	FOS like 2, AP-1 transcription factor subunit. (323 aa)
	ESR2	Uncharacterized protein. (568 aa)
	FEZF2	FEZ family zinc finger 2. (436 aa)
	CNTN4	Uncharacterized protein. (1073 aa)
	SULF2	Extracellular sulfatase. (916 aa)
	RHOB	Ras homolog family member B. (196 aa)
	PLS3	Plastin 3. (677 aa)
	PAX6	Paired box 6. (447 aa)
	MGP	Matrix Gla protein. (104 aa)
	GABRE	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (455 aa)
	CADPS2	Uncharacterized protein. (1301 aa)
	LMO3	LIM domain only 3. (156 aa)
	CRHR2	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (427 aa)
	PLPP4	acidPPc domain-containing protein. (271 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (503 aa)
	SYF2	Pre-mRNA-splicing factor SYF2. (320 aa)
	LMO1	Putative LIM domain only 1 variant 2. (157 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (1044 aa)
	STMN1	Stathmin; Belongs to the stathmin family. (175 aa)
	GRIK1	Glutamate ionotropic receptor kainate type subunit 1. (924 aa)
	ZBTB20	Zinc finger and BTB domain containing 20. (756 aa)
	HPCAL1	Hippocalcin-like protein 1. (193 aa)
	KCNQ5	Potassium voltage-gated channel subfamily Q member 5. (902 aa)
	HTR1B	5-hydroxytryptamine receptor 1B. (377 aa)
	KCTD12	Potassium channel tetramerization domain containing 12. (159 aa)
	NKX2-1	NK2 homeobox 1. (366 aa)
	ZEB2	Zinc finger E-box binding homeobox 2. (1224 aa)
	EGR1	Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...] (510 aa)
	SCN3B	Ig-like domain-containing protein. (384 aa)
	KCTD20	Potassium channel tetramerization domain containing 20. (477 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	CYP19A1	ENSTGUP00000002859	ENSTGUP00000007225	Androgen receptor.	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	0.731
AR	ESR1	ENSTGUP00000002859	ENSTGUP00000011604	Androgen receptor.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily.	0.728
AR	ESR2	ENSTGUP00000002859	ENSTGUP00000029826	Androgen receptor.	Uncharacterized protein.	0.451
AR	ETV1	ENSTGUP00000002859	ENSTGUP00000033785	Androgen receptor.	ETS variant 1.	0.548
C1QL3	HPCAL1	ENSTGUP00000001364	ENSTGUP00000013431	Complement C1q like 3.	Hippocalcin-like protein 1.	0.442
C1QL3	KCTD20	ENSTGUP00000001364	ENSTGUP00000000944	Complement C1q like 3.	Potassium channel tetramerization domain containing 20.	0.417
C1QL3	SCUBE2	ENSTGUP00000001364	ENSTGUP00000008559	Complement C1q like 3.	Signal peptide, CUB domain and EGF like domain containing 2.	0.410
CADPS2	FOSL2	ENSTGUP00000024447	ENSTGUP00000033698	Uncharacterized protein.	FOS like 2, AP-1 transcription factor subunit.	0.600
CADPS2	GRIK3	ENSTGUP00000024447	ENSTGUP00000001636	Uncharacterized protein.	Uncharacterized protein.	0.737
CADPS2	KCTD20	ENSTGUP00000024447	ENSTGUP00000000944	Uncharacterized protein.	Potassium channel tetramerization domain containing 20.	0.764
CADPS2	LMO1	ENSTGUP00000024447	ENSTGUP00000018379	Uncharacterized protein.	Putative LIM domain only 1 variant 2.	0.754
CADPS2	LMO3	ENSTGUP00000024447	ENSTGUP00000023643	Uncharacterized protein.	LIM domain only 3.	0.739
CADPS2	PLPP4	ENSTGUP00000024447	ENSTGUP00000022666	Uncharacterized protein.	acidPPc domain-containing protein.	0.764
CADPS2	SLC24A2	ENSTGUP00000024447	ENSTGUP00000004451	Uncharacterized protein.	Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.736
CADPS2	ZEB2	ENSTGUP00000024447	ENSTGUP00000012270	Uncharacterized protein.	Zinc finger E-box binding homeobox 2.	0.733
CAMK2N1	NECAB2	ENSTGUP00000019552	ENSTGUP00000007029	Calcium/calmodulin-dependent protein kinase II inhibitor 1.	N-terminal EF-hand calcium binding protein 2.	0.406
CAMK2N1	PLPP4	ENSTGUP00000019552	ENSTGUP00000022666	Calcium/calmodulin-dependent protein kinase II inhibitor 1.	acidPPc domain-containing protein.	0.406
CAMKK1	CNTN4	ENSTGUP00000004335	ENSTGUP00000028638	Calcium/calmodulin dependent protein kinase kinase 1; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.550
CAMKK1	GABRE	ENSTGUP00000004335	ENSTGUP00000024507	Calcium/calmodulin dependent protein kinase kinase 1; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.764
CAMKK1	HTR2A	ENSTGUP00000004335	ENSTGUP00000020169	Calcium/calmodulin dependent protein kinase kinase 1; Belongs to the protein kinase superfamily.	5-hydroxytryptamine receptor 2A.	0.764