(22 nodes) (2021) Pathogenicity and virulence of West Nile virus revisited eight decades after its first isolation. network (Taeniopygia guttata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SNCA	Alpha-synuclein; Belongs to the synuclein family. (201 aa)
	IRF7	IRF-3 domain-containing protein. (555 aa)
	LOC115498461	Death-associated protein kinase 2 isoform X5. (392 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1047 aa)
	NTPCR	AAA domain-containing protein. (236 aa)
	CCR5	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	MERTK	MER proto-oncogene, tyrosine kinase. (982 aa)
	MMP9	Matrix metallopeptidase 9. (723 aa)
	ATF6	Activating transcription factor 6. (724 aa)
	CD4	Ig-like domain-containing protein. (396 aa)
	IL17A	Uncharacterized protein. (150 aa)
	MAVS	CARD_2 domain-containing protein. (627 aa)
	TYRO3	TYRO3 protein tyrosine kinase. (872 aa)
	STAT1	Signal transducer and activator of transcription. (755 aa)
	FURIN	Furin, paired basic amino acid cleaving enzyme. (789 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (896 aa)
	CD40	CD40 molecule. (280 aa)
	DAPK2	Death associated protein kinase 2; Belongs to the protein kinase superfamily. (487 aa)
	STAT3	Signal transducer and activator of transcription. (811 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	DAPK3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (456 aa)
	DAPK1	Uncharacterized protein. (1430 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF6	FURIN	ENSTGUP00000017350	ENSTGUP00000010478	Activating transcription factor 6.	Furin, paired basic amino acid cleaving enzyme.	0.420
CCR5	CCR7	ENSTGUP00000021568	ENSTGUP00000002421	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.734
CCR5	CD4	ENSTGUP00000021568	ENSTGUP00000013698	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Ig-like domain-containing protein.	0.943
CCR5	CD40	ENSTGUP00000021568	ENSTGUP00000005997	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	CD40 molecule.	0.444
CCR5	IL17A	ENSTGUP00000021568	ENSTGUP00000013665	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.418
CCR5	TLR7	ENSTGUP00000021568	ENSTGUP00000032154	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.487
CCR7	CCR5	ENSTGUP00000002421	ENSTGUP00000021568	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.734
CCR7	CD4	ENSTGUP00000002421	ENSTGUP00000013698	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Ig-like domain-containing protein.	0.724
CCR7	CD40	ENSTGUP00000002421	ENSTGUP00000005997	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	CD40 molecule.	0.626
CCR7	IL17A	ENSTGUP00000002421	ENSTGUP00000013665	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.520
CD4	CCR5	ENSTGUP00000013698	ENSTGUP00000021568	Ig-like domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.943
CD4	CCR7	ENSTGUP00000013698	ENSTGUP00000002421	Ig-like domain-containing protein.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.724
CD4	CD40	ENSTGUP00000013698	ENSTGUP00000005997	Ig-like domain-containing protein.	CD40 molecule.	0.677
CD4	FURIN	ENSTGUP00000013698	ENSTGUP00000010478	Ig-like domain-containing protein.	Furin, paired basic amino acid cleaving enzyme.	0.414
CD4	IL17A	ENSTGUP00000013698	ENSTGUP00000013665	Ig-like domain-containing protein.	Uncharacterized protein.	0.682
CD4	STAT3	ENSTGUP00000013698	ENSTGUP00000002670	Ig-like domain-containing protein.	Signal transducer and activator of transcription.	0.597
CD4	TLR3	ENSTGUP00000013698	ENSTGUP00000007089	Ig-like domain-containing protein.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.638
CD4	TLR7	ENSTGUP00000013698	ENSTGUP00000032154	Ig-like domain-containing protein.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.614
CD40	CCR5	ENSTGUP00000005997	ENSTGUP00000021568	CD40 molecule.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.444
CD40	CCR7	ENSTGUP00000005997	ENSTGUP00000002421	CD40 molecule.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.626