98 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRB14	Growth factor receptor bound protein 14. (157 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (582 aa)
	HCK	Tyrosine-protein kinase. (508 aa)
	SH2B3	SH2B adaptor protein 3. (579 aa)
	SUPT6H	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1681 aa)
	SH2D4B	SH2 domain containing 4B. (475 aa)
	JAK2	Tyrosine-protein kinase. (1130 aa)
	SHF	Src homology 2 domain containing F. (239 aa)
	SRC	Tyrosine-protein kinase. (553 aa)
	SOCS1	Suppressor of cytokine signaling 1. (207 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (846 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
	SH2B2	SH2B adaptor protein 2. (708 aa)
	SH2D1A	SH2 domain containing 1A. (125 aa)
	DAPP1	Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (242 aa)
	SOCS3	Suppressor of cytokine signaling 3. (209 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	LOC100222691	SH2 domain-containing protein. (1057 aa)
	STAT3	Signal transducer and activator of transcription. (811 aa)
	H0YUH5_TAEGU	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1052 aa)
	LCP2	Lymphocyte cytosolic protein 2. (530 aa)
	LCK	Protein kinase domain-containing protein. (513 aa)
	RASA1	RAS p21 protein activator 1. (996 aa)
	ITK	Tyrosine-protein kinase. (631 aa)
	SHC2	PID domain-containing protein. (600 aa)
	SHC3	SHC adaptor protein 3. (632 aa)
	SYK	Tyrosine-protein kinase. (668 aa)
	SHD	Src homology 2 domain containing transforming protein D. (277 aa)
	SH2D3C	SH2 domain containing 3C. (931 aa)
	GRAP2	Uncharacterized protein. (296 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	TNS3	Tensin 3. (1476 aa)
	ENSTGUP00000034337	annotation not available (812 aa)
	STAT4	Signal transducer and activator of transcription 4. (749 aa)
	SOCS6	Suppressor of cytokine signaling 6. (534 aa)
	SH2D5	PID domain-containing protein. (460 aa)
	LOC115496244	Tyrosine-protein kinase. (1148 aa)
	TYK2	Non-receptor tyrosine-protein kinase TYK2. (1175 aa)
	TNS1	Tensin 1. (1853 aa)
	SH2D2A	SH2 domain containing 2A. (590 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (840 aa)
	CISH	Cytokine inducible SH2 containing protein. (257 aa)
	TNS2	Tensin 2. (785 aa)
	LOC100225312	SH2 domain-containing protein. (227 aa)
	CLNK	Cytokine-dependent hematopoietic cell linker. (394 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (831 aa)
	CRKL	Uncharacterized protein. (303 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (878 aa)
	CRK	Uncharacterized protein. (305 aa)
	SOCS4	Suppressor of cytokine signaling 4. (436 aa)
	TXK	TXK tyrosine kinase. (546 aa)
	ABL1	Tyrosine-protein kinase. (1139 aa)
	SH2D4A	SH2 domain-containing protein. (453 aa)
	SHB	SH2 domain-containing protein. (641 aa)
	LYN	Tyrosine-protein kinase. (605 aa)
	SHE	Src homology 2 domain containing E. (460 aa)
	FGR	Tyrosine-protein kinase. (617 aa)
	CHN1	Chimerin 1. (696 aa)
	RIN2	Ras and Rab interactor 2. (888 aa)
	LOC100225168	Tyrosine-protein kinase CSK. (450 aa)
	SOCS5	Suppressor of cytokine signaling 5. (535 aa)
	SOCS7	Suppressor of cytokine signaling 7. (522 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	INPP5D	Inositol polyphosphate-5-phosphatase D. (1214 aa)
	LOC100228920	Tyrosine-protein kinase JAK1. (1225 aa)
	CHN2	Rho-GAP domain-containing protein. (518 aa)
	BLNK	Uncharacterized protein. (601 aa)
	LOC100222362	Phosphoinositide phospholipase C. (1311 aa)
	TNS4	Tensin 4. (728 aa)
	ENSTGUP00000020611	annotation not available (824 aa)
	PIK3R2	Uncharacterized protein. (727 aa)
	BCAR3	BCAR3 adaptor protein, NSP family member. (893 aa)
	ENSTGUP00000020196	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1. (1281 aa)
	GRAP	Uncharacterized protein. (358 aa)
	INPPL1	Uncharacterized protein. (1323 aa)
	SHC1	SHC adaptor protein 1. (609 aa)
	ABL2	Tyrosine-protein kinase. (1160 aa)
	ZAP70	Tyrosine-protein kinase. (609 aa)
	MATK	Tyrosine-protein kinase. (443 aa)
	JAK3	Janus kinase 3. (1113 aa)
	STAT6	Signal transducer and activator of transcription 6. (932 aa)
	BTK	Tyrosine-protein kinase. (662 aa)
	CBLB	Cbl proto-oncogene B. (1025 aa)
	SH2D1B	SH2 domain-containing protein. (170 aa)
	BLK	Tyrosine-protein kinase. (499 aa)
	RIN3	Ras and Rab interactor 3. (968 aa)
	SLA	Src like adaptor. (270 aa)
	FRK	Tyrosine-protein kinase. (527 aa)
	STAT1	Signal transducer and activator of transcription. (755 aa)
	SH3BP2	SH3 domain binding protein 2. (546 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	NCK2	NCK adaptor protein 2. (380 aa)
	GRB2	Putative growth factor receptor-bound protein 2. (217 aa)
	LOC100221185	Uncharacterized protein. (738 aa)
	TEC	Tyrosine-protein kinase. (630 aa)
	GRB10	Growth factor receptor bound protein 10. (596 aa)
	SRMS	Tyrosine-protein kinase. (491 aa)
	SHC4	SHC adaptor protein 4. (634 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSTGUP00000026063	ENSTGUP00000018887	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
ABL1	CBLB	ENSTGUP00000026063	ENSTGUP00000014016	Tyrosine-protein kinase.	Cbl proto-oncogene B.	0.563
ABL1	CRK	ENSTGUP00000026063	ENSTGUP00000027704	Tyrosine-protein kinase.	Uncharacterized protein.	0.978
ABL1	CRKL	ENSTGUP00000026063	ENSTGUP00000028203	Tyrosine-protein kinase.	Uncharacterized protein.	0.967
ABL1	GRB2	ENSTGUP00000026063	ENSTGUP00000008899	Tyrosine-protein kinase.	Putative growth factor receptor-bound protein 2.	0.669
ABL1	NCK2	ENSTGUP00000026063	ENSTGUP00000010036	Tyrosine-protein kinase.	NCK adaptor protein 2.	0.509
ABL2	ABL1	ENSTGUP00000018887	ENSTGUP00000026063	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
ABL2	CBLB	ENSTGUP00000018887	ENSTGUP00000014016	Tyrosine-protein kinase.	Cbl proto-oncogene B.	0.563
ABL2	CRK	ENSTGUP00000018887	ENSTGUP00000027704	Tyrosine-protein kinase.	Uncharacterized protein.	0.978
ABL2	CRKL	ENSTGUP00000018887	ENSTGUP00000028203	Tyrosine-protein kinase.	Uncharacterized protein.	0.967
ABL2	GRB2	ENSTGUP00000018887	ENSTGUP00000008899	Tyrosine-protein kinase.	Putative growth factor receptor-bound protein 2.	0.669
ABL2	NCK2	ENSTGUP00000018887	ENSTGUP00000010036	Tyrosine-protein kinase.	NCK adaptor protein 2.	0.509
BLK	BLNK	ENSTGUP00000013694	ENSTGUP00000021186	Tyrosine-protein kinase.	Uncharacterized protein.	0.405
BLK	CBLB	ENSTGUP00000013694	ENSTGUP00000014016	Tyrosine-protein kinase.	Cbl proto-oncogene B.	0.486
BLK	CRK	ENSTGUP00000013694	ENSTGUP00000027704	Tyrosine-protein kinase.	Uncharacterized protein.	0.440
BLK	CRKL	ENSTGUP00000013694	ENSTGUP00000028203	Tyrosine-protein kinase.	Uncharacterized protein.	0.440
BLK	FER	ENSTGUP00000013694	ENSTGUP00000035485	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.418
BLK	FES	ENSTGUP00000013694	ENSTGUP00000029426	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.450
BLK	GRAP2	ENSTGUP00000013694	ENSTGUP00000036174	Tyrosine-protein kinase.	Uncharacterized protein.	0.474
BLK	GRB2	ENSTGUP00000013694	ENSTGUP00000008899	Tyrosine-protein kinase.	Putative growth factor receptor-bound protein 2.	0.555